General Information of the Compound
Compound ID
CP0275523
Compound Name
[6-[4-[(4-phenylbenzoyl)amino]butyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-yl] methanesulfonate
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Structure
Formula
C31H38N2O4S
Molecular Weight
534.722
Canonical SMILES
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2OS(C)(=O)=O
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InChI
InChI=1S/C31H38N2O4S/c1-3-21-33(28-18-19-29-27(23-28)12-9-13-30(29)37-38(2,35)36)22-8-7-20-32-31(34)26-16-14-25(15-17-26)24-10-5-4-6-11-24/h4-6,9-17,28H,3,7-8,18-23H2,1-2H3,(H,32,34)
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InChIKey
HYHZGIWTSKSXKP-UHFFFAOYSA-N
Physicochemical Property
logP
5.4715
Rotatable Bonds
12
Heavy Atom Count
38
Polar Areas
75.71
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10414769
SID: 15432470
ChEMBL ID
CHEMBL291801
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 251.19 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.259 nM
   TI
   LI
   LO
   TS