Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
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 PubChem ID
CID: 3038495
SID: 14782328
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1
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Compound Formula C26H31N3O2
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  7
1
EC50 = 1.8 nM
   TI
   LI
   LO
   TS
2
Ki = 0.67 nM
   TI
   LI
   LO
   TS
3
Ki = 0.91 nM
   TI
   LI
   LO
   TS
4
Ki = 0.92 nM
   TI
   LI
   LO
   TS
5
Ki = 1.3 nM
   TI
   LI
   LO
   TS
6
Ki = 1.413 nM
   TI
   LI
   LO
   TS
7
Ki = 4.6 nM
   TI
   LI
   LO
   TS
CL000389 CHO-DXB11
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1.8 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.4 nM