General Information of the Compound
Compound ID
CP0401590
Compound Name
N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
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Structure
Formula
C18H26N2O3S
Molecular Weight
350.484
Canonical SMILES
CCN(CC)Cc1ccc([nH]1)-c1cc(ccc1OC)S(=O)(=O)CC
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InChI
InChI=1S/C18H26N2O3S/c1-5-20(6-2)13-14-8-10-17(19-14)16-12-15(24(21,22)7-3)9-11-18(16)23-4/h8-12,19H,5-7,13H2,1-4H3
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InChIKey
VMATXNORBZBLAE-UHFFFAOYSA-N
Physicochemical Property
logP
3.3257
Rotatable Bonds
8
Heavy Atom Count
24
Polar Areas
62.4
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 22403055
ChEMBL ID
CHEMBL277684
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 39.81 nM
   TI
   LI
   LO
   TS