Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
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 PubChem ID
CID: 9826580
SID: 14785761
Canonical SMILES
Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccccn3)CC2)c1Cl
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Compound Formula C26H28Cl2N4O
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 6.3 nM
   TI
   LI
   LO
   TS
2
Ki = 0.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.5 nM