General Information of the Compound
Compound ID
CP0437040
Compound Name
4-bromo-N-[4-[4-(2,5-dimethoxyphenyl)piperazin-1-yl]butyl]benzamide
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Structure
Formula
C23H30BrN3O3
Molecular Weight
476.415
Canonical SMILES
COc1ccc(OC)c(c1)N1CCN(CCCCNC(=O)c2ccc(Br)cc2)CC1
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InChI
InChI=1S/C23H30BrN3O3/c1-29-20-9-10-22(30-2)21(17-20)27-15-13-26(14-16-27)12-4-3-11-25-23(28)18-5-7-19(24)8-6-18/h5-10,17H,3-4,11-16H2,1-2H3,(H,25,28)
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InChIKey
XYWCAOFTBSFDJW-UHFFFAOYSA-N
Physicochemical Property
logP
3.7985
Rotatable Bonds
9
Heavy Atom Count
30
Polar Areas
54.04
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44311009
ChEMBL ID
CHEMBL70866
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.162 nM
   TI
   LI
   LO
   TS