General Information of the Compound
Compound ID
CP0859404
Compound Name
1-{2-[5-(3-Chloro-phenyl)-1,1-dioxo-1lambda*6*-[1,2,5]thiadiazolidin-2-yl]-ethyl}-azepane
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Structure
Formula
C16H24ClN3O2S
Molecular Weight
357.907
Canonical SMILES
O=S1(=O)N(CCN2CCCCCC2)CCN1c1cccc(Cl)c1
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InChI
InChI=1S/C16H24ClN3O2S/c17-15-6-5-7-16(14-15)20-13-12-19(23(20,21)22)11-10-18-8-3-1-2-4-9-18/h5-7,14H,1-4,8-13H2
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InChIKey
VRQBYXDBZXNLRA-UHFFFAOYSA-N
Physicochemical Property
logP
2.5828
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
43.86
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46881412
ChEMBL ID
CHEMBL1084121
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
2
Ki = 199.53 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 > 3162.28 nM
   TI
   LI
   LO
   TS
2
Ki = 316.23 nM
   TI
   LI
   LO
   TS