General Information of the Compound
Compound ID
CP0848297
Compound Name
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-phenyl-propionamide oxalic acid
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Structure
Formula
C26H35N3O6
Molecular Weight
485.581
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)CCc2ccccc2)CC1.O=C(O)C(=O)O
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InChI
InChI=1S/C24H33N3O2.C2H2O4/c1-29-23-12-6-5-11-22(23)27-19-17-26(18-20-27)16-8-7-15-25-24(28)14-13-21-9-3-2-4-10-21;3-1(4)2(5)6/h2-6,9-12H,7-8,13-20H2,1H3,(H,25,28);(H,3,4)(H,5,6)
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InChIKey
LCCWMVVEPXAGPM-UHFFFAOYSA-N
Physicochemical Property
logP
2.502
Rotatable Bonds
10
Heavy Atom Count
35
Polar Areas
119.41
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44350908
ChEMBL ID
CHEMBL340173
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 48.7 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4.8 nM
   TI
   LI
   LO
   TS