General Information of the Compound
Compound ID
CP0376420
Compound Name
N-[4-[(4aR,10bR)-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
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Structure
Formula
C30H34N2O
Molecular Weight
438.615
Canonical SMILES
O=C(NCCCCN1CCC[C@H]2[C@H]1CCc1ccccc21)c1ccc(cc1)-c1ccccc1
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InChI
InChI=1S/C30H34N2O/c33-30(26-16-14-24(15-17-26)23-9-2-1-3-10-23)31-20-6-7-21-32-22-8-13-28-27-12-5-4-11-25(27)18-19-29(28)32/h1-5,9-12,14-17,28-29H,6-8,13,18-22H2,(H,31,33)/t28-,29-/m1/s1
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InChIKey
OPJTVMKUVYOWNC-FQLXRVMXSA-N
Physicochemical Property
logP
6.058
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44329068
ChEMBL ID
CHEMBL95743
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 15.85 nM
   TI
   LI
   LO
   TS