General Information of the Compound
Compound ID
CP0426895
Compound Name
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]naphthalene-2-carboxamide
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Structure
Formula
C32H35N3O
Molecular Weight
477.652
Canonical SMILES
O=C(NCCCCN1CCN(CC1)C(c1ccccc1)c1ccccc1)c1ccc2ccccc2c1
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InChI
InChI=1S/C32H35N3O/c36-32(30-18-17-26-11-7-8-16-29(26)25-30)33-19-9-10-20-34-21-23-35(24-22-34)31(27-12-3-1-4-13-27)28-14-5-2-6-15-28/h1-8,11-18,25,31H,9-10,19-24H2,(H,33,36)
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InChIKey
DQNYAPGMAYPLKE-UHFFFAOYSA-N
Physicochemical Property
logP
5.757
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
35.58
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44436721
ChEMBL ID
CHEMBL240588
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 457 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 11.1 nM
   TI
   LI
   LO
   TS