General Information of the Compound
Compound ID
CP0154055
Compound Name
6-[4-[(4-phenylbenzoyl)amino]butyl-propylamino]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
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Structure
Formula
C31H37N3O2
Molecular Weight
483.656
Canonical SMILES
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2C(N)=O
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InChI
InChI=1S/C31H37N3O2/c1-2-20-34(27-17-18-28-26(22-27)11-8-12-29(28)30(32)35)21-7-6-19-33-31(36)25-15-13-24(14-16-25)23-9-4-3-5-10-23/h3-5,8-16,27H,2,6-7,17-22H2,1H3,(H2,32,35)(H,33,36)
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InChIKey
LKZYQJSJNFLIIO-UHFFFAOYSA-N
Physicochemical Property
logP
5.232
Rotatable Bonds
11
Heavy Atom Count
36
Polar Areas
75.43
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 19592141
ChEMBL ID
CHEMBL59960
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.981 nM
   TI
   LI
   LO
   TS