General Information of the Compound
Compound ID
CP0434836
Compound Name
(4aR,10bR)-N,N-dimethyl-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
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Structure
Formula
C18H26N2O2
Molecular Weight
302.418
Canonical SMILES
CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(=O)N(C)C
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InChI
InChI=1S/C18H26N2O2/c1-4-9-20-10-11-22-17-15-12-14(18(21)19(2)3)6-5-13(15)7-8-16(17)20/h5-6,12,16-17H,4,7-11H2,1-3H3/t16-,17-/m1/s1
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InChIKey
UDEAASQJJIGOTN-IAGOWNOFSA-N
Physicochemical Property
logP
2.4865
Rotatable Bonds
3
Heavy Atom Count
22
Polar Areas
32.78
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 15389746
ChEMBL ID
CHEMBL485029
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1862.09 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS