Compound Information

General Information of the Compound

Compound ID

CP0008601

Compound Name

4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)

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Synonyms

Aldo

Aloperidin

Aloperidin (TN)

Aloperidol

Aloperidolo

Aloperidolo [DCIT]

Aloperidolo [Italian]

Aloperidon

Apo-Haloperidol

Bioperidolo

Bioperidolo (TN)

Brotopon

Brotopon (TN)

Dozic

Dozic (TN)

Dozix

Duraperidol (TN)

Einalon S

Einalon S (TN)

Eukystol

Eukystol (TN)

Fortunan

Galoperidol

H 1512

Haldol

Haldol (TN)

Haldol La

Haldol Solutab

Halidol

Halojust

Halol

Halopal

Haloperido

Haloperidol

Haloperidol (JP15/USP)

Haloperidol (JP15/USP/INN)

Haloperidol [USAN:INN:BAN:JAN]

Haloperidolum

Haloperidolum [INN-Latin]

Halopidol

Halopoidol

Halosten

Halosten (TN)

Keselan

Keselan (TN)

Lealgin compositum

Linton

Linton (TN);Novo-Peridol

McN-JR-1625

Mixidol

Pekuces

Peluces

Peluces (TN)

Peridol

Pernox

Pms Haloperidol

R 1625

R-1625

Serenace

Serenace (TN)

Serenase

Serenase (TN)

Serenelfi

Sernas

Sernel

Sigaperidol

Sigaperidol (TN)

Ulcolind

Uliolind

Vesalium

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Structure

Formula

C21H23ClFNO2

Molecular Weight

375.871

Canonical SMILES

OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1

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InChI

InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

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InChIKey

LNEPOXFFQSENCJ-UHFFFAOYSA-N

CAS

52-86-8

Physicochemical Property

logP	4.4256
Rotatable Bonds	6
Heavy Atom Count	26
Polar Areas	40.54
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Complexity	26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID

CID: 3559

SID: 14902191

ChEMBL ID

CHEMBL54

DrugBank ID

DB00502

Map of Molecular Bioactivity Related to the Compound

Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Compound

Protein ID: PT00819, 5-hydroxytryptamine receptor 1A

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 1703 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 2800 nM
2	Ki = 3600 nM

Protein ID: PT00825, 5-hydroxytryptamine receptor 2A

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000234	AU-BEK Cell Line Info	Bos taurus (Bovine)	2
1	IC50 = 288 nM Bioactivity Info	TI LI LO TS
2	Ki = 108 nM Bioactivity Info	TI LI LO TS
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	Ki = 22.91 nM Bioactivity Info	TI LI LO TS
2	Ki = 89 nM Bioactivity Info	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	Ki = 100 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 25 nM
2	Ki = 100 nM
3	Ki = 120 nM
4	Ki = 130 nM
5	Ki = 165.96 nM
6	Ki = 435 nM

Protein ID: PT01354, 5-hydroxytryptamine receptor 6

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 1083 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 6000 nM
2	Ki > 5000 nM

Protein ID: PT00941, 5-hydroxytryptamine receptor 7

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 408 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01195, D(1A) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 6.166 nM
2	Ki = 49 nM
3	Ki = 82 nM
4	Ki = 107 nM
5	Ki = 120 nM
6	Ki = 270 nM

Protein ID: PT01169, D(1B) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 48 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 38 nM
2	Ki = 58 nM
3	Ki = 260 nM

Protein ID: PT01005, D(2) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	10
1	IC50 = 0.16 nM Bioactivity Info	TI LI LO TS
2	Kd = 0.4898 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.44 nM Bioactivity Info	TI LI LO TS
4	Ki = 0.4677 nM Bioactivity Info	TI LI LO TS
5	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
6	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
7	Ki = 1.862 nM Bioactivity Info	TI LI LO TS
8	Ki = 3.25 nM Bioactivity Info	TI LI LO TS
9	Ki = 4 nM Bioactivity Info	TI LI LO TS
10	Ki > 217 nM Bioactivity Info	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	9
1	IC50 = 550 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.85 nM Bioactivity Info	TI LI LO TS
3	Ki = 1 nM Bioactivity Info	TI LI LO TS
4	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
5	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
6	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
7	Ki = 2 nM Bioactivity Info	TI LI LO TS
8	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
9	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
CL000041	LTK- Cell Line Info	Mus musculus (Mouse)	2
1	Ki = 0.16 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.44 nM Bioactivity Info	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	16
1	Ki = 0.25 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.42 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.81 nM Bioactivity Info	TI LI LO TS
4	Ki = 0.84 nM Bioactivity Info	TI LI LO TS
5	Ki = 0.85 nM Bioactivity Info	TI LI LO TS
6	Ki = 0.87 nM Bioactivity Info	TI LI LO TS
7	Ki = 0.96 nM Bioactivity Info	TI LI LO TS
8	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
9	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
10	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
11	Ki = 2 nM Bioactivity Info	TI LI LO TS
12	Ki = 3 nM Bioactivity Info	TI LI LO TS
13	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
14	Ki = 4.8 nM Bioactivity Info	TI LI LO TS
15	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
16	Ki = 18 nM Bioactivity Info	TI LI LO TS
CL000025	HEK-293T Cell Line Info	Homo sapiens (Human)	1
1	Ki = 0.263 nM Bioactivity Info	TI LI LO TS
CL000049	C6 Cell Line Info	Rattus norvegicus (Rat)	2
1	Ki = 4.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 6400 nM Bioactivity Info	TI LI LO TS
CL000013	Sf9 Cell Line Info	Spodoptera frugiperda (Fall armyworm)	1
1	Ki = 8.5 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	IC50 = 4 nM
2	IC50 = 4.1 nM
3	IC50 = 4.9 nM
4	Ki = 0.12 nM
5	Ki = 0.16 nM
6	Ki = 0.5 nM
7	Ki = 0.6026 nM
8	Ki = 0.66 nM
9	Ki = 0.7 nM
10	Ki = 0.74 nM
11	Ki = 0.7943 nM
12	Ki = 0.89 nM
13	Ki = 0.8913 nM
14	Ki = 1 nM
15	Ki = 1.1 nM
16	Ki = 1.122 nM
17	Ki = 1.3 nM
18	Ki = 1.4 nM
19	Ki = 1.5 nM
20	Ki = 1.97 nM
21	Ki = 2 nM
22	Ki = 2.2 nM
23	Ki = 2.5 nM
24	Ki = 2.6 nM
25	Ki = 2.61 nM
26	Ki = 2.84 nM
27	Ki = 3 nM
28	Ki = 3.6 nM
29	Ki = 3.7 nM
30	Ki = 4.2 nM
31	Ki = 5.58 nM
32	Ki = 9.6 nM

Protein ID: PT00957, D(2) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CL000053	COS-7 Cell Line Info	Chlorocebus aethiops (Green monkey)	2
1	Ki = 1.01 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.63 nM Bioactivity Info	TI LI LO TS
CL000013	Sf9 Cell Line Info	Spodoptera frugiperda (Fall armyworm)	1
1	Ki = 7.6 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	IC50 = 2.5 nM
2	IC50 = 5.5 nM
3	IC50 = 7 nM
4	IC50 = 7.5 nM
5	IC50 = 17.5 nM
6	IC50 = 18 nM
7	IC50 = 40 nM
8	Ki = 0.2 nM
9	Ki = 0.47 nM
10	Ki = 0.75 nM
11	Ki = 0.871 nM
12	Ki = 1.4 nM
13	Ki = 1.5 nM
14	Ki = 1.86 nM
15	Ki = 2.6 nM
16	Ki = 2.69 nM
17	Ki = 3.311 nM
18	Ki = 4 nM
19	Ki = 4.365 nM
20	Ki = 4.8 nM
21	Ki = 5.012 nM

Protein ID: PT01734, D(2) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	Ki = 0.3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.7 nM Bioactivity Info	TI LI LO TS

Protein ID: PT00943, D(3) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000043	U2OS Cell Line Info	Homo sapiens (Human)	1
1	IC50 = 0.06 nM Bioactivity Info	TI LI LO TS
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	4
1	IC50 = 0.25 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.96 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
4	Ki = 6.4 nM Bioactivity Info	TI LI LO TS
CL000025	HEK-293T Cell Line Info	Homo sapiens (Human)	3
1	IC50 = 3.467 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.122 nM Bioactivity Info	TI LI LO TS
3	Ki = 16.04 nM Bioactivity Info	TI LI LO TS
CL000013	Sf9 Cell Line Info	Spodoptera frugiperda (Fall armyworm)	2
1	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
2	Ki = 18 nM Bioactivity Info	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	14
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
4	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
5	Ki = 2.6 nM Bioactivity Info	TI LI LO TS
6	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
7	Ki = 6.3 nM Bioactivity Info	TI LI LO TS
8	Ki = 6.4 nM Bioactivity Info	TI LI LO TS
9	Ki = 6.8 nM Bioactivity Info	TI LI LO TS
10	Ki = 7.5 nM Bioactivity Info	TI LI LO TS
11	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
12	Ki = 8.318 nM Bioactivity Info	TI LI LO TS
13	Ki = 16 nM Bioactivity Info	TI LI LO TS
14	Ki = 25 nM Bioactivity Info	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	3
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
2	Ki = 12.7 nM Bioactivity Info	TI LI LO TS
3	Ki = 29 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	IC50 = 10 nM
2	Ki = 0.69 nM
3	Ki = 2.5 nM
4	Ki = 2.74 nM
5	Ki = 4.4 nM
6	Ki = 4.571 nM
7	Ki = 4.6 nM
8	Ki = 5.5 nM
9	Ki = 7.8 nM
10	Ki = 10 nM
11	Ki = 10.4 nM
12	Ki = 11.48 nM
13	Ki = 13.5 nM
14	Ki = 16 nM
15	Ki = 21 nM

Protein ID: PT01366, D(3) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000053	COS-7 Cell Line Info	Chlorocebus aethiops (Green monkey)	2
1	Ki = 5.04 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.57 nM Bioactivity Info	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	Ki = 6.4 nM Bioactivity Info	TI LI LO TS
CL000013	Sf9 Cell Line Info	Spodoptera frugiperda (Fall armyworm)	3
1	Ki = 14.3 nM Bioactivity Info	TI LI LO TS
2	Ki = 18 nM Bioactivity Info	TI LI LO TS
3	Ki = 47 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 3 nM
2	Ki = 28 nM

Protein ID: PT01161, D(4) dopamine receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	3
1	EC50 > 10000 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
3	Ki = 5 nM Bioactivity Info	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	14
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
2	Ki = 1 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
4	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
5	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
6	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
7	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
8	Ki = 6 nM Bioactivity Info	TI LI LO TS
9	Ki = 6.026 nM Bioactivity Info	TI LI LO TS
10	Ki = 6.3 nM Bioactivity Info	TI LI LO TS
11	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
12	Ki = 7.3 nM Bioactivity Info	TI LI LO TS
13	Ki = 42 nM Bioactivity Info	TI LI LO TS
14	Ki = 103 nM Bioactivity Info	TI LI LO TS
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CL000013	Sf9 Cell Line Info	Spodoptera frugiperda (Fall armyworm)	2
1	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.6 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	IC50 = 1.3 nM
2	IC50 = 5 nM
3	IC50 = 6.5 nM
4	Ki = 0.74 nM
5	Ki = 1 nM
6	Ki = 1.4 nM
7	Ki = 1.585 nM
8	Ki = 1.9 nM
9	Ki = 2.3 nM
10	Ki = 3.3 nM
11	Ki = 3.8 nM
12	Ki = 5 nM
13	Ki = 7 nM
14	Ki = 7.3 nM
15	Ki = 7.94 nM
16	Ki = 10 nM
17	Ki = 10.47 nM
18	Ki = 11 nM
19	Ki = 12.7 nM

Protein ID: PT02591, Major prion protein

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000235	ScN2a Cell Line Info	Mus musculus (Mouse)	1
1	EC50 > 10000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01515, Mu-type opioid receptor

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	EC50 > 10000 nM Bioactivity Info	TI LI LO TS
2	Ki > 10000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01310, Muscarinic acetylcholine receptor M1

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000026	CHO-K1 Cell Line Info	Cricetulus griseus (Chinese hamster)	1
1	IC50 = 5500 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	Ki = 1600 nM

Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	4
1	IC50 = 28.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 230 nM Bioactivity Info	TI LI LO TS
3	IC50 = 1160 nM Bioactivity Info	TI LI LO TS
4	Ki = 120 nM Bioactivity Info	TI LI LO TS
CL000083	MCF-7 Cell Line Info	Homo sapiens (Human)	1
1	IC50 = 28.18 nM Bioactivity Info	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	3
1	IC50 = 30.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 32 nM Bioactivity Info	TI LI LO TS
3	IC50 = 1100 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	IC50 = 10 nM
2	IC50 = 26.8 nM
3	IC50 = 26.92 nM
4	IC50 = 30.2 nM
5	IC50 = 1400 nM

Protein ID: PT01065, Serine/threonine-protein kinase mTOR

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL001056	MEF-1 [Mouse fibroblast] Cell Line Info	Mus musculus (Mouse)	1
1	Potency = 23280.9 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01509, Sigma non-opioid intracellular receptor 1

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000001	Jurkat Cell Line Info	Homo sapiens (Human)	5
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
3	Ki = 7.762 nM Bioactivity Info	TI LI LO TS
4	Ki = 8.8 nM Bioactivity Info	TI LI LO TS
5	Ki = 11.9 nM Bioactivity Info	TI LI LO TS
CL000196	MDA-MB-468 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 0.21 nM Bioactivity Info	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	4
1	Ki = 2 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
3	Ki = 5.9 nM Bioactivity Info	TI LI LO TS
4	Ki = 7 nM Bioactivity Info	TI LI LO TS
CL000186	RPMI-8226 Cell Line Info	Homo sapiens (Human)	1
1	Ki = 40 nM Bioactivity Info	TI LI LO TS

Biochemical Assays

1	IC50 = 5.64 nM
2	IC50 = 213.8 nM
3	Ki = 0.2 nM
4	Ki = 0.44 nM
5	Ki = 1.1 nM
6	Ki = 1.9 nM
7	Ki = 2.2 nM
8	Ki = 2.5 nM
9	Ki = 3.7 nM
10	Ki = 5 nM
11	Ki = 6.3 nM
12	Ki = 6.4 nM
13	Ki = 16 nM

Protein ID: PT05156, Vesicular acetylcholine transporter

Protein Info

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000868	PC12 Cell Line Info	Rattus norvegicus (Rat)	1
1	Ki = 391 nM Bioactivity Info	TI LI LO TS

Cell Viability or Cytotoxicity Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000683	DAN-G Cell Line Info	Homo sapiens (Human)	1
1	IC50 > 20000 nM	TI LI LO TS

Clinical Information about the Compound

Drug 1 ( Haloperidol )

Drug Name	Haloperidol
Company	Janssen Pharmaceutica
Indication	Schizophrenia Approved
Target(s)	Dopamine D2 receptor (D2R) Target Info Antagonist

Drug 2 ( Haloperidol )

Drug Name	Haloperidol
Indication	Schizophrenia Approved Coronavirus Disease 2019 (COVID-19) Investigative
Target(s)	HUMAN opioid receptor sigma 1 (OPRS1) Target Info Modulator HUMAN sigma intracellular receptor 2 (TMEM97) Target Info Modulator

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han