General Information of the Cell Line
Cell Line ID
CL000868
Cell Line Name
PC12
Synonyms
PC-12
PC 12
PC12.1
Category
Cancer cell line
Organism
Rattus norvegicus (Rat)
Tissue Information
Adrenal gland
Disease
Rat adrenal gland pheochromocytoma (NCIt: C121568)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01608, Adenosine receptor A2a
Compound ID Compound Name Compound Formula
CP0167160
(S)-N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(3-fluoro-5-(1-methylpyrrolidin-3-yloxy)phenyl)pyrimidin-4-yl)acetamide
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C22H25FN6O2
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0373930
N-[6-(3,5-dimethoxyphenyl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]acetamide
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C19H21N5O3
 1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CP0541912
N-[2-(3,5-dimethylpyrazol-1-yl)-6-[3-(1-methylpyrrolidin-3-yl)oxyphenyl]pyrimidin-4-yl]acetamide
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C22H26N6O2
 1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
CP0496583
1-Methyl-2-phenyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
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C14H13N5O
 1
1
Ki = 17200 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Adrenal gland)
Cell Line Name Organism Disease
NCI-H295R Homo sapiens (Human) Adrenal cortex carcinoma
SW13 Homo sapiens (Human) Adrenal cortex carcinoma
Y1 Mus musculus (Mouse) Mouse adrenal cortical carcinoma
123.7 Rattus norvegicus (Rat) Rat adrenal gland pheochromocytoma
CAD Mus musculus (Mouse) -