| Compound ID |
Compound Name |
Compound Formula |
|
CP0375123
|
(2R,3R)-3-(4-(aminomethyl)-4-phenylpiperidin-1-yl)-5-iodo-1,2,3,4-tetrahydronaphthalen-2-ol
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|
C22H27IN2O
|
1
|
| 1 |
Kd = 3 nM
|
|
|
|
CP0096000
|
(2R,3R)-3-(4-Phenyl-piperidin-1-yl)-1,2,3,4-tetrahydro-naphthalen-2-ol
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|
C21H25NO
|
1
|
| 1 |
Ki = 0.055 nM
|
|
|
|
CP0207181
|
(3'R,4'R)-1'-(4-Fluoro-benzyl)-4-phenyl-[1,3']bipiperidinyl-4'-ol
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|
C23H29FN2O
|
1
|
| 1 |
Ki = 0.22 nM
|
|
|
|
CP0896249
|
(+/-)-trans-2-Hydroxy-3-(4-(4-bromobenzoyl)piperidino)tetralin Hydrochloride
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|
C22H25BrClNO2
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0501862
|
(2R,3R)-5-(3-iodoallyloxy)-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol
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|
C24H28INO2
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0415506
|
(+/-)-trans-2-Hydroxy-3-(4-(4-nitrobenzoyl)piperidino)tetralin
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|
C22H24N2O4
|
1
|
| 1 |
Ki = 0.48 nM
|
|
|
|
CP0460091
|
(2R,3R)-5-(3-fluoropropoxy)-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol
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|
C24H30FNO2
|
1
|
| 1 |
Ki = 0.77 nM
|
|
|
|
CP0965651
|
(-)-[11C]-(1-(3-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-piperidin-4-yl)(4-(methylamino)phenyl)methanone
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|
C23H28N2O2
|
1
|
| 1 |
Ki = 0.78 nM
|
|
|
|
CP0540395
|
[4-(dimethylamino)phenyl]-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]methanone
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|
C24H30N2O2
|
1
|
| 1 |
Ki = 0.93 nM
|
|
|
|
CP0443987
|
(+/-)-trans-2-Hydroxy-3-(4-(4-aminobenzoyl)piperidino)tetralin
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|
C22H26N2O2
|
1
|
| 1 |
Ki = 1.68 nM
|
|
|
|
CP0045885
|
(1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol
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|
C17H25NO
|
2
|
| 1 |
Ki = 2 nM
|
|
|
| 2 |
Ki = 15.2 nM
|
|
|
|
CP0088567
|
(+)-trans-(4-fluorophenyl)(1-(3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)piperidin-4-yl)methanone
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|
C22H24FNO2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0444043
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-[4-(methylamino)phenyl]methanone
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|
C23H28N2O2
|
1
|
| 1 |
Ki = 3.03 nM
|
|
|
|
CP0867839
|
(+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetralin Hydrochloride
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|
C22H26ClNO2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0456242
|
(+/-)-trans-2-Hydroxy-3-(4-benzoylpiperidino)tetralin Hydrochloride
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|
C22H25NO2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0540396
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-thiophen-2-ylmethanone
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|
C20H23NO2S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0457261
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(6-methoxypyridin-3-yl)methanone
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki = 8.36 nM
|
|
|
|
CP0456240
|
(5-fluoropyridin-3-yl)-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]methanone
Show/Hide
|
C21H23FN2O2
|
1
|
| 1 |
Ki = 10.1 nM
|
|
|
|
CP0875691
|
((3'R,4'R)-4'-hydroxy-1'-(3-methylthiophene-2-carbonyl)-1,3'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
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|
C26H32N2O8S
|
1
|
| 1 |
Ki = 10.2 nM
|
|
|
|
CP0460090
|
(1R,2R,4S)-4-(4-fluorobenzyloxy)-2-(4-phenylpiperidin-1-yl)cyclohexanol
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|
C24H30FNO2
|
1
|
| 1 |
Ki = 10.7 nM
|
|
|
|
CP0879668
|
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(3-methylthiophen-2-yl)methanone oxalate
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|
C25H29FN2O7S
|
1
|
| 1 |
Ki = 11.4 nM
|
|
|
|
CP0456239
|
(2-fluoropyridin-3-yl)-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]methanone
Show/Hide
|
C21H23FN2O2
|
1
|
| 1 |
Ki = 12.7 nM
|
|
|
|
CP0907122
|
((3'R,4'R)-1'-benzoyl-4'-hydroxy-1,3'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
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|
C27H32N2O8
|
1
|
| 1 |
Ki = 15.4 nM
|
|
|
|
CP0456241
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(1-methylpyrrol-2-yl)methanone
Show/Hide
|
C21H26N2O2
|
1
|
| 1 |
Ki = 18.4 nM
|
|
|
|
CP0877877
|
((3'R,4'R)-4'-hydroxy-1'-(thiophene-2-carbonyl)-1,3'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C25H30N2O8S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0540394
|
[1-(3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)piperidin-4-yl]-[4-(methylamino)phenyl]methanone
Show/Hide
|
C23H28N2O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0444042
|
[1-[(2R,3R)-8-amino-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(6-methoxypyridin-3-yl)methanone
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
Ki = 23.3 nM
|
|
|
|
CP0482630
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-pyridin-3-ylmethanone
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
Ki = 24.1 nM
|
|
|
|
CP0482628
|
(6-fluoropyridin-3-yl)-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]methanone
Show/Hide
|
C21H23FN2O2
|
1
|
| 1 |
Ki = 26.1 nM
|
|
|
|
CP0403974
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(1-methylpyrrol-3-yl)methanone
Show/Hide
|
C21H26N2O2
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
|
CP0482629
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(6-methylpyridin-3-yl)methanone
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
Ki = 27.9 nM
|
|
|
|
CP0540422
|
[6-(2-fluoroethoxy)pyridin-3-yl]-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]methanone
Show/Hide
|
C23H27FN2O3
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0570673
|
[1-[(2R,3R)-8-amino-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(1-methylpyrrol-2-yl)methanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 38.7 nM
|
|
|
|
CP0467348
|
[1-[(2R,3R)-8-amino-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(6-methylpyridin-3-yl)methanone
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0945778
|
((3'R,4'R)-1'-benzoyl-4'-hydroxy-1,3'-bipiperidin-4-yl)(4-fluorophenyl)methanone oxalate
Show/Hide
|
C26H29FN2O7
|
1
|
| 1 |
Ki = 62.7 nM
|
|
|
|
CP0487856
|
4-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidine-4-carbonyl]-1-methylpyridin-2-one
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki = 66.2 nM
|
|
|
|
CP0457259
|
[3-(2-fluoroethoxy)pyridin-2-yl]-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]methanone
Show/Hide
|
C23H27FN2O3
|
1
|
| 1 |
Ki = 76.4 nM
|
|
|
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CP0871712
|
((3'R,4'R)-4'-hydroxy-1'-nicotinoyl-1,3'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C26H31N3O8
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0467349
|
[1-[(2R,3R)-8-amino-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-pyridin-3-ylmethanone
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 118 nM
|
|
|
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CP0457260
|
[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(3-methoxypyridin-2-yl)methanone
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki = 121 nM
|
|
|
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CP0938284
|
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(thiophen-2-yl)methanone oxalate
Show/Hide
|
C24H27FN2O7S
|
1
|
| 1 |
Ki = 123 nM
|
|
|
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CP0867696
|
((3'R,4'R)-4'-hydroxy-1'-(5-methylthiophene-2-carbonyl)-1,3'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C26H32N2O8S
|
1
|
| 1 |
Ki = 142 nM
|
|
|
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CP0525050
|
6-[1-[(2R,3R)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidine-4-carbonyl]-1-methylpyridin-2-one
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki = 182 nM
|
|
|
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CP0953956
|
((3'R,4'R)-3'-hydroxy-1'-(thiophene-2-carbonyl)-1,4'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C25H30N2O8S
|
1
|
| 1 |
Ki = 206 nM
|
|
|
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CP0879669
|
((3'R,4'R)-1'-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C27H31FN2O8
|
1
|
| 1 |
Ki = 233 nM
|
|
|
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CP0501078
|
(1R,2R,5R)-5-(4-fluorobenzyloxy)-2-(4-phenylpiperidin-1-yl)cyclohexanol
Show/Hide
|
C24H30FNO2
|
1
|
| 1 |
Ki = 330 nM
|
|
|
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CP0912792
|
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(pyridin-3-yl)methanone oxalate
Show/Hide
|
C25H28FN3O7
|
1
|
| 1 |
Ki = 810 nM
|
|
|
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CP0879667
|
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(5-methylthiophen-2-yl)methanone oxalate
Show/Hide
|
C25H29FN2O7S
|
1
|
| 1 |
Ki = 1190 nM
|
|
|
|
CP0875692
|
((3'R,4'R)-4-(4-fluorobenzoyl)-3'-hydroxy-1,4'-bipiperidin-1'-yl)(thiophen-2-yl)methanone oxalate
Show/Hide
|
C24H27FN2O7S
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
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CP0879070
|
((3'R,4'R)-3'-hydroxy-1'-(5-methylthiophene-2-carbonyl)-1,4'-bipiperidin-4-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C26H32N2O8S
|
1
|
| 1 |
Ki = 1350 nM
|
|
|
|
CP0877878
|
((3'R,4'R)-4-(4-fluorobenzoyl)-3'-hydroxy-1,4'-bipiperidin-1'-yl)(3-methylthiophen-2-yl)methanone oxalate
Show/Hide
|
C25H29FN2O7S
|
1
|
| 1 |
Ki = 2020 nM
|
|
|
|
CP0482627
|
[1-[(2R,3R)-5-amino-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]piperidin-4-yl]-(1-methylpyrrol-2-yl)methanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 2310 nM
|
|
|
|
CP0908152
|
((3'R,4'R)-4'-hydroxy-1,3'-bipiperidine-1',4-diyl)bis((4-methoxyphenyl)methanone)oxalate
Show/Hide
|
C28H34N2O9
|
1
|
| 1 |
Ki = 3020 nM
|
|
|
|
CP0926280
|
((3'R,4'R)-4'-hydroxy-1,3'-bipiperidine-1',4-diyl)bis((4-fluorophenyl)methanone)oxalate
Show/Hide
|
C26H28F2N2O7
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
|
CP0862998
|
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(4-methoxyphenyl)methanone oxalate
Show/Hide
|
C27H31FN2O8
|
1
|
| 1 |
Ki = 13000 nM
|
|
|
