General Information of the Compound
Compound ID
CP0912792
Compound Name
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(pyridin-3-yl)methanone oxalate
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Structure
Formula
C25H28FN3O7
Molecular Weight
501.511
Canonical SMILES
O=C(O)C(=O)O.O=C(c1ccc(F)cc1)C1CCN([C@@H]2CN(C(=O)c3cccnc3)CC[C@H]2O)CC1
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InChI
InChI=1S/C23H26FN3O3.C2H2O4/c24-19-5-3-16(4-6-19)22(29)17-7-11-26(12-8-17)20-15-27(13-9-21(20)28)23(30)18-2-1-10-25-14-18;3-1(4)2(5)6/h1-6,10,14,17,20-21,28H,7-9,11-13,15H2;(H,3,4)(H,5,6)/t20-,21-;/m1./s1
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InChIKey
FJTFIAKHQNOXPD-MUCZFFFMSA-N
Physicochemical Property
logP
1.5466
Rotatable Bonds
4
Heavy Atom Count
36
Polar Areas
148.34
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 70686207
ChEMBL ID
CHEMBL2047123
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02273, Vesicular acetylcholine transporter
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
Ki = 810 nM
   TI
   LI
   LO
   TS