General Information of the Compound
Compound ID
CP0879668
Compound Name
((3'R,4'R)-4-(4-fluorobenzoyl)-4'-hydroxy-1,3'-bipiperidin-1'-yl)(3-methylthiophen-2-yl)methanone oxalate
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Structure
Formula
C25H29FN2O7S
Molecular Weight
520.579
Canonical SMILES
Cc1ccsc1C(=O)N1CC[C@@H](O)[C@H](N2CCC(C(=O)c3ccc(F)cc3)CC2)C1.O=C(O)C(=O)O
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InChI
InChI=1S/C23H27FN2O3S.C2H2O4/c1-15-9-13-30-22(15)23(29)26-12-8-20(27)19(14-26)25-10-6-17(7-11-25)21(28)16-2-4-18(24)5-3-16;3-1(4)2(5)6/h2-5,9,13,17,19-20,27H,6-8,10-12,14H2,1H3;(H,3,4)(H,5,6)/t19-,20-;/m1./s1
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InChIKey
BEKFPTUJBPPAPD-GZJHNZOKSA-N
Physicochemical Property
logP
2.52152
Rotatable Bonds
4
Heavy Atom Count
36
Polar Areas
135.45
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 70696608
ChEMBL ID
CHEMBL2047126
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02273, Vesicular acetylcholine transporter
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
Ki = 11.4 nM
   TI
   LI
   LO
   TS