General Information of the Compound
Compound ID
CP0945778
Compound Name
((3'R,4'R)-1'-benzoyl-4'-hydroxy-1,3'-bipiperidin-4-yl)(4-fluorophenyl)methanone oxalate
    Show/Hide
Structure
Formula
C26H29FN2O7
Molecular Weight
500.523
Canonical SMILES
O=C(O)C(=O)O.O=C(c1ccc(F)cc1)C1CCN([C@@H]2CN(C(=O)c3ccccc3)CC[C@H]2O)CC1
    Show/Hide
InChI
InChI=1S/C24H27FN2O3.C2H2O4/c25-20-8-6-17(7-9-20)23(29)18-10-13-26(14-11-18)21-16-27(15-12-22(21)28)24(30)19-4-2-1-3-5-19;3-1(4)2(5)6/h1-9,18,21-22,28H,10-16H2;(H,3,4)(H,5,6)/t21-,22-;/m1./s1
    Show/Hide
InChIKey
LTQTZBIQEOEKKY-HLUKFBSCSA-N
Physicochemical Property
logP
2.1516
Rotatable Bonds
4
Heavy Atom Count
36
Polar Areas
135.45
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 70696606
ChEMBL ID
CHEMBL2047122
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02273, Vesicular acetylcholine transporter
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
Ki = 62.7 nM
   TI
   LI
   LO
   TS