General Information of the Cell Line
Cell Line ID
CL000392
Cell Line Name
Y1
Synonyms
Y-1
Y 1
Clone Y-1
Clone Y1
GM05384
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0585
Tissue Information
Adrenal gland
Disease
Mouse adrenal cortical carcinoma (NCIt: C22992)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02026, Alpha-2B adrenergic receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0393344
 Compound Info 
AGN-190837
   Show/Hide
C12H22N2O
  1
1
Ki = 5.888 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0403325
 Compound Info 
N-[(1S,2R)-2-(2-phenylethyl)cyclohexyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C17H24N2O
  1
1
Ki = 6.918 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0410755
 Compound Info 
N-[(1S,2R)-2-phenylcyclohexyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C15H20N2O
  1
1
Ki = 22.39 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0464022
 Compound Info 
N-[(1S,2R)-2-(3-phenylpropyl)cyclohexyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C18H26N2O
  1
1
Ki = 32.36 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0041550
 Compound Info 
BRIMONIDINE
   Show/Hide
C11H10BrN5
  1
1
Ki = 34.67 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0455126
 Compound Info 
N-[(1S,2R)-2-benzylcyclohexyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C16H22N2O
  1
1
Ki = 40.74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0461049
 Compound Info 
N-[(2R,3S)-3-benzyl-2-bicyclo[2.2.1]heptanyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C17H22N2O
  1
1
Ki = 40.74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0048455
 Compound Info 
N-(4,5-dihydro-1H-imidazol-2-yl)-5-iodoquinoxalin-6-amine
   Show/Hide
C11H10IN5
  1
1
Ki = 42.66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0225412
 Compound Info 
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-1,2,3,4-tetrahydroquinoxalin-6-amine
   Show/Hide
C11H14BrN5
  1
1
Ki = 48.98 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0079425
 Compound Info 
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
   Show/Hide
C11H10ClN5
  1
1
Ki = 69.18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0437331
 Compound Info 
N-[(2R,3S)-3-propyl-2-bicyclo[2.2.1]heptanyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C13H22N2O
  1
1
Ki = 91.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383504
 Compound Info 
N-[(2R,3S)-3-[(E)-3-phenylprop-2-enyl]-2-bicyclo[2.2.1]heptanyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C19H24N2O
  1
1
Ki = 102.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380408
 Compound Info 
N-[(2R,3S)-3-(3-phenylpropyl)-2-bicyclo[2.2.1]heptanyl]-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C19H26N2O
  1
1
Ki = 141.25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0052015
 Compound Info 
N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
   Show/Hide
C11H11N5
  1
1
Ki = 218.78 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0039358
 Compound Info 
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-2-methylquinoxalin-6-amine
   Show/Hide
C12H12BrN5
  1
1
Ki = 323.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058790
 Compound Info 
5-bromo-N-(5-methyl-4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
   Show/Hide
C12H12BrN5
  1
1
Ki = 3235.94 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0274492
 Compound Info 
N-(5-bromoquinoxalin-6-yl)-4,5-dihydro-1,3-thiazol-2-amine
   Show/Hide
C11H9BrN4S
  1
1
Ki = 17378.01 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0299657
 Compound Info 
N-[(3aR,7aS)-3a,4,5,6,7,7a-hexahydro-1H-benzimidazol-2-yl]-5-bromoquinoxalin-6-amine
   Show/Hide
C15H16BrN5
  1
1
Ki = 18197.01 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0059937
 Compound Info 
N-(5-bromoquinoxalin-6-yl)-4,5-dihydro-1,3-oxazol-2-amine
   Show/Hide
C11H9BrN4O
  1
1
Ki = 85113.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT02992, Adrenocorticotropic hormone receptor
 Protein Info 
Protein ID: PT01431, Melanocortin receptor 4
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Adrenal gland)
Cell Line Name Organism Disease
NCI-H295R
 Cell Line Info 
Homo sapiens (Human) Adrenal cortex carcinoma
SW13
 Cell Line Info 
Homo sapiens (Human) Adrenal cortex carcinoma
PC12
 Cell Line Info 
Rattus norvegicus (Rat) Rat adrenal gland pheochromocytoma
123.7
 Cell Line Info 
Rattus norvegicus (Rat) Rat adrenal gland pheochromocytoma
CAD
 Cell Line Info 
Mus musculus (Mouse) -