| Compound ID |
Compound Name |
Compound Formula |
|
CP0153573
|
(3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(methylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C8H12F2N2O3S
|
1
|
| 1 |
EC50 = 1.71 nM
|
|
|
|
CP0350494
|
(3aR,5R,6R,7S,7aR)-7-fluoro-5-(hydroxymethyl)-2-(methylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazol-6-ol
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|
C8H13FN2O3S
|
1
|
| 1 |
EC50 = 10.6 nM
|
|
|
|
CP0153551
|
(3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL
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|
C9H16N2O4S
|
1
|
| 1 |
EC50 = 13.5 nM
|
|
|
|
CP0362985
|
(3aR,5R,6S,7R,7aR)-2-(azetidin-1-yl)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C10H16N2O4S
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0229371
|
US9243020, 20
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|
C9H14F2N2O3S
|
1
|
| 1 |
EC50 = 31.2 nM
|
|
|
|
CP0204614
|
(3aR,5R,6S,7aR)-5-(hydroxymethyl)-2-methylimino-1,3a,5,6,7,7a-hexahydropyrano[3,2-d][1,3]thiazol-6-ol
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|
C8H14N2O3S
|
1
|
| 1 |
EC50 = 33.1 nM
|
|
|
|
CP0340760
|
US9243020, 17
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|
C8H13FN2O3S
|
1
|
| 1 |
EC50 = 34.4 nM
|
|
|
|
CP0138321
|
(3aR,5R,6S,7R,7aR)-2-[ethyl(methyl)amino]-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C10H18N2O4S
|
1
|
| 1 |
EC50 = 36.7 nM
|
|
|
|
CP0197802
|
(3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(propylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C10H16F2N2O3S
|
1
|
| 1 |
EC50 = 41.4 nM
|
|
|
|
CP0138332
|
US9243020, 19
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|
C9H14F2N2O3S
|
1
|
| 1 |
EC50 = 52.7 nM
|
|
|
|
CP0334591
|
US9243020, 33
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|
C8H11F3N2O2S
|
1
|
| 1 |
EC50 = 58.2 nM
|
|
|
|
CP0366393
|
(3aR,5S,6S,7R,7aR)-5-(fluoromethyl)-2-(propylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C10H17FN2O3S
|
1
|
| 1 |
EC50 = 119 nM
|
|
|
|
CP0188048
|
US8927507, 16
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|
C11H18N2O4S
|
1
|
| 1 |
EC50 = 152 nM
|
|
|
|
CP0174235
|
US8933040, 7
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|
C11H18N2O4S
|
1
|
| 1 |
EC50 = 165 nM
|
|
|
|
CP0328173
|
(3aR,5S,6S,7R,7aR)-2-ethylimino-5-(fluoromethyl)-1,3a,5,6,7,7a-hexahydropyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C9H15FN2O3S
|
1
|
| 1 |
EC50 = 176 nM
|
|
|
|
CP0362986
|
(3aR,5S,6S,7R,7aR)-2-(dimethylamino)-5-(fluoromethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C9H15FN2O3S
|
1
|
| 1 |
EC50 = 177 nM
|
|
|
|
CP0350493
|
(3aR,5R,6S,7aR)-5-(hydroxymethyl)-2-(propylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazol-6-ol
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|
C10H18N2O3S
|
1
|
| 1 |
EC50 = 224 nM
|
|
|
|
CP0138316
|
US9243020, 9
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|
C8H13FN2O3S
|
1
|
| 1 |
EC50 = 307 nM
|
|
|
|
CP0234675
|
(3aR,5S,6R,7S,7aR)-7-fluoro-5-(fluoromethyl)-2-(methylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazol-6-ol
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|
C8H12F2N2O2S
|
1
|
| 1 |
EC50 = 328 nM
|
|
|
|
CP0229370
|
US9243020, 4
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|
C9H16N2O3S
|
1
|
| 1 |
EC50 = 358 nM
|
|
|
|
CP0064837
|
US9243020, 2
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|
C9H16N2O3S
|
1
|
| 1 |
EC50 = 364 nM
|
|
|
|
CP0198503
|
(3aR,5R,6R,7R,7aR)-2-(ethylamino)-7-fluoro-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazol-6-ol
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|
C9H15FN2O3S
|
1
|
| 1 |
EC50 = 443 nM
|
|
|
|
CP0366394
|
(3aR,5R,6R,7R,7aR)-7-fluoro-5-(hydroxymethyl)-2-(propylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazol-6-ol
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|
C10H17FN2O3S
|
1
|
| 1 |
EC50 = 445 nM
|
|
|
|
CP0270320
|
(3aR,5R,6S,7R,7aR)-2-(2-fluoroethylimino)-5-(hydroxymethyl)-1,3a,5,6,7,7a-hexahydropyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C9H15FN2O4S
|
1
|
| 1 |
EC50 = 509 nM
|
|
|
|
CP0204613
|
(3aR,5S,6S,7R,7aR)-2-amino-5-(difluoromethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
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|
C7H10F2N2O3S
|
1
|
| 1 |
EC50 = 2400 nM
|
|
|
