General Information of the Compound
Compound ID
CP0204614
Compound Name
(3aR,5R,6S,7aR)-5-(hydroxymethyl)-2-methylimino-1,3a,5,6,7,7a-hexahydropyrano[3,2-d][1,3]thiazol-6-ol
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Structure
Formula
C8H14N2O3S
Molecular Weight
218.278
Canonical SMILES
CNC1=N[C@@H]2C[C@H](O)[C@@H](CO)O[C@@H]2S1
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InChI
InChI=1S/C8H14N2O3S/c1-9-8-10-4-2-5(12)6(3-11)13-7(4)14-8/h4-7,11-12H,2-3H2,1H3,(H,9,10)/t4-,5+,6-,7-/m1/s1
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InChIKey
UMXYJFMLLLIFPW-XZBKPIIZSA-N
Physicochemical Property
logP
-0.8546
Rotatable Bonds
1
Heavy Atom Count
14
Polar Areas
74.08
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
14

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 136416827
SID: 137278300
ChEMBL ID
CHEMBL4516713
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06114, Protein O-GlcNAcase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
EC50 = 33.1 nM
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   LI
   LO
   TS