General Information of the Cell Line
Cell Line ID
CL001056
Cell Line Name
MEF-1 [Mouse fibroblast]
Synonyms
MEF1
Mouse Embryo Fibroblast-1
Category
Transformed cell line
Organism
Mus musculus (Mouse)
Tissue Information
Embryo
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01028, Ephrin type-B receptor 4
Compound ID Compound Name Compound Formula
CP0128740
6-butyl-4-methyl-7-(2-methylphenyl)purino[7,8-a]imidazole-1,3-dione
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C19H21N5O2
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0128742
6-butyl-7-(4-fluoro-2-methylphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
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C19H20FN5O2
 1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
CP0039399
8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydroxyphenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
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C22H19N5O4
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0078397
6-butyl-7-[5-(1H-indazol-4-yl)-2-methylphenyl]-4-methylpurino[7,8-a]imidazole-1,3-dione
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C26H25N7O2
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0449284
4-methyl-7-(2-methylphenyl)-6-pentylpurino[7,8-a]imidazole-1,3-dione
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C20H23N5O2
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0440945
6-butyl-7-(2-chlorophenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
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C18H18ClN5O2
 1
1
IC50 = 270 nM
   TI
   LI
   LO
   TS
CP0392382
7-(2-chlorophenyl)-6-(2-methoxyphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
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C21H16ClN5O3
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Embryo)
Cell Line Name Organism Disease
Bm5 Bombyx mori (Silk moth) -
Schneider 2 Drosophila melanogaster (Fruit fly) -
NIH 3T3 Mus musculus (Mouse) -
BALB/3T3 clone A31 Mus musculus (Mouse) -
NIH-3T3-G185 Mus musculus (Mouse) -
HER14 Mus musculus (Mouse) -
B104-1-1 Mus musculus (Mouse) -
3T3-L1 Mus musculus (Mouse) -
C3H/10T1/2 clone 8 Mus musculus (Mouse) -
Shh Light II Mus musculus (Mouse) -
MEF3.8 Mus musculus (Mouse) -
NIH 3T3-ras Mus musculus (Mouse) -
NIH-3T3-A14 Mus musculus (Mouse) -
3T3/HH FlashII-7 Mus musculus (Mouse) -
TSC1-/- MEF Mus musculus (Mouse) -
Ptch-deficient MEF Mus musculus (Mouse) -
Rat1 Rattus norvegicus (Rat) -
REF52 Rattus norvegicus (Rat) -
SR-3Y1-1 Rattus norvegicus (Rat) -
SAE Squalus acanthias (Spiny dogfish) -
BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper) -