Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000387
Cell Line Name	C3H/10T1/2 clone 8
Synonyms	C3H/10T1/2-clone8 C3H/10T1/2 CL8 C3H10T1/2 clone8 C3H10T1/2CL8 10T1/2(clone8) 10T1/2 C3H10T1-2 C3H10T1/2 C3H-10T1/2 C3H 10T1/2 C3H/10T1/2
Category	Spontaneously immortalized cell line
Organism	Mus musculus (Mouse)
Cellosaurus ID	CVCL_0190
Tissue Information	Embryo
Disease	None

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT02397, Protein smoothened

Protein Info

Compound ID	Compound Name	Compound Formula
CP0416443 Compound Info	N-(2,4-dimethyl-5-pyridin-2-ylphenyl)-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C26H23N3O2	1
1	EC50 = 0.8 nM Bioactivity Info	TI LI LO TS
CP0388713 Compound Info	N-[2,4-dimethyl-5-(4-methyl-1,3-thiazol-2-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H23N3O2S	1
1	EC50 = 0.9 nM Bioactivity Info	TI LI LO TS
CP0134521 Compound Info	N-[5-(1H-imidazol-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H22N4O2	1
1	EC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0578103 Compound Info	N-[5-(5-aminopyridin-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C26H24N4O2	1
1	EC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0564424 Compound Info	N-[2,4-dimethyl-5-(5-methyl-1H-pyrazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H24N4O2	1
1	EC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0437816 Compound Info	N-[5-(6-aminopyridazin-3-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H23N5O2	1
1	EC50 < 1.5 nM Bioactivity Info	TI LI LO TS
CP0549318 Compound Info	N-[5-(6-aminopyridin-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C26H24N4O2	1
1	EC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0562076 Compound Info	N-(2,4-dimethyl-5-pyridin-3-ylphenyl)-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C26H23N3O2	1
1	EC50 = 2.3 nM Bioactivity Info	TI LI LO TS
CP0357751 Compound Info	N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H24N4O2	1
1	EC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0388712 Compound Info	N-[4-chloro-5-(1,2-dimethylimidazol-4-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H23ClN4O2	1
1	EC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0479111 Compound Info	N-[2,4-dimethyl-5-(2-methyl-1H-imidazol-5-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H24N4O2	1
1	EC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0388714 Compound Info	N-[2,4-dimethyl-5-(1,3,5-trimethylpyrazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C27H28N4O2	1
1	EC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0437815 Compound Info	N-[5-(1H-benzimidazol-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C28H24N4O2	1
1	EC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0068085 Compound Info	2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide Show/Hide	C19H14Cl2N2O3S	2
1	EC50 = 4.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0228021 Compound Info	N-[2-methyl-5-(2-methyl-1H-imidazol-5-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H22N4O2	1
1	EC50 = 6.7 nM Bioactivity Info	TI LI LO TS
CP0560303 Compound Info	N-[4-chloro-2-methyl-5-(1-methylimidazol-2-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H21ClN4O2	1
1	EC50 = 6.8 nM Bioactivity Info	TI LI LO TS
CP0557562 Compound Info	N-[4-chloro-5-(1H-imidazol-2-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C23H19ClN4O2	1
1	EC50 = 7.5 nM Bioactivity Info	TI LI LO TS
CP0119723 Compound Info	N-[5-(1H-imidazol-2-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C23H20N4O2	1
1	EC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0163912 Compound Info	N-[3-(1H-imidazol-2-yl)-2,6-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H22N4O2	1
1	EC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0137307 Compound Info	N-[4-fluoro-5-(1H-imidazol-2-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C23H19FN4O2	1
1	EC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0262749 Compound Info	N-[2-methyl-5-(1-methylimidazol-2-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H22N4O2	1
1	EC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0247151 Compound Info	N-[2-methyl-5-(5-methyl-1H-imidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H22N4O2	1
1	EC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0388711 Compound Info	N-[4-chloro-2-methyl-5-(1-methylimidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H21ClN4O2	1
1	EC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0358355 Compound Info	N-[5-(1,2-dimethylimidazol-4-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H24N4O2	1
1	EC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0557564 Compound Info	N-[5-(2,3-dimethylimidazol-4-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C25H24N4O2	1
1	EC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0236876 Compound Info	N-[5-(1H-imidazol-5-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C23H20N4O2	1
1	EC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0290960 Compound Info	N-[2-methyl-5-(1-methylimidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide Show/Hide	C24H22N4O2	1
1	EC50 = 89 nM Bioactivity Info	TI LI LO TS
CP0046415 Compound Info	3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide Show/Hide	C28H28ClN3OS	1
1	EC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0179058 Compound Info	propyl 4-[(4-hydroxy-6,7-dimethoxy-2-oxo-1-propylquinoline-3-carbonyl)amino]benzoate Show/Hide	C25H28N2O7	1
1	EC50 = 360 nM Bioactivity Info	TI LI LO TS
CP0179234 Compound Info	4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoic acid Show/Hide	C23H24N2O5	1
1	EC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0376778 Compound Info	butyl 4-[(4-hydroxy-2-oxo-1-pentylquinoline-3-carbonyl)amino]benzoate Show/Hide	C26H30N2O5	1
1	EC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0395766 Compound Info	propyl 4-[(4-hydroxy-2-oxo-1-pentylquinoline-3-carbonyl)amino]benzoate Show/Hide	C25H28N2O5	1
1	EC50 = 700 nM Bioactivity Info	TI LI LO TS
CP0046821 Compound Info	9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine Show/Hide	C31H32N6O2	1
1	EC50 = 800 nM Bioactivity Info	TI LI LO TS
CP0376777 Compound Info	propyl 4-[(4-hydroxy-2-oxo-1-azatricyclo[7.3.1.05,13]trideca-3,5,7,9(13)-tetraene-3-carbonyl)amino]benzoate Show/Hide	C23H22N2O5	1
1	EC50 = 800 nM Bioactivity Info	TI LI LO TS
CP0477632 Compound Info	propyl 4-[(1-butyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C24H26N2O5	1
1	EC50 = 800 nM Bioactivity Info	TI LI LO TS
CP0445722 Compound Info	ethyl 4-[(4-hydroxy-2-oxo-1-pentylquinoline-3-carbonyl)amino]benzoate Show/Hide	C24H26N2O5	1
1	EC50 = 900 nM Bioactivity Info	TI LI LO TS
CP0300549 Compound Info	propyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C26H30N2O5	1
1	EC50 = 1200 nM Bioactivity Info	TI LI LO TS
CP0376780 Compound Info	propyl 4-[(4-hydroxy-6-methyl-2-oxo-1-propylquinoline-3-carbonyl)amino]benzoate Show/Hide	C24H26N2O5	1
1	EC50 = 1200 nM Bioactivity Info	TI LI LO TS
CP0470856 Compound Info	butyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C27H32N2O5	1
1	EC50 = 1500 nM Bioactivity Info	TI LI LO TS
CP0376765 Compound Info	benzyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C30H30N2O5	1
1	EC50 = 2000 nM Bioactivity Info	TI LI LO TS
CP0445718 Compound Info	propyl 4-[(6-fluoro-4-hydroxy-2-oxo-1-propylquinoline-3-carbonyl)amino]benzoate Show/Hide	C23H23FN2O5	1
1	EC50 = 2400 nM Bioactivity Info	TI LI LO TS
CP0376764 Compound Info	propyl 4-[(4-hydroxy-2-oxo-1-propylquinoline-3-carbonyl)amino]benzoate Show/Hide	C23H24N2O5	1
1	EC50 = 2600 nM Bioactivity Info	TI LI LO TS
CP0514519 Compound Info	tert-butyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C27H32N2O5	1
1	EC50 = 3100 nM Bioactivity Info	TI LI LO TS
CP0485693 Compound Info	propyl 4-[(4-hydroxy-2-oxo-1-prop-2-enylquinoline-3-carbonyl)amino]benzoate Show/Hide	C23H22N2O5	1
1	EC50 = 3400 nM Bioactivity Info	TI LI LO TS
CP0525447 Compound Info	ethyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C25H28N2O5	1
1	EC50 = 3600 nM Bioactivity Info	TI LI LO TS
CP0445719 Compound Info	propyl 4-[(6-chloro-4-hydroxy-2-oxo-1-propylquinoline-3-carbonyl)amino]benzoate Show/Hide	C23H23ClN2O5	1
1	EC50 = 4900 nM Bioactivity Info	TI LI LO TS
CP0376781 Compound Info	N-[4-(butylcarbamoyl)phenyl]-1-hexyl-4-hydroxy-2-oxoquinoline-3-carboxamide Show/Hide	C27H33N3O4	1
1	EC50 = 5800 nM Bioactivity Info	TI LI LO TS
CP0445721 Compound Info	propan-2-yl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate Show/Hide	C26H30N2O5	1
1	EC50 = 6500 nM Bioactivity Info	TI LI LO TS
CP0125184 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea Show/Hide	C21H22N6O	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0436299 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea Show/Hide	C21H22F3N5O	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0526933 Compound Info	N-[3-(1H-benzimidazol-2-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide Show/Hide	C22H17N3O3	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0526935 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-chlorophenyl)urea Show/Hide	C20H22ClN5O	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0437680 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-methoxyphenyl)urea Show/Hide	C21H25N5O2	1
1	IC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0410295 Compound Info	N-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide Show/Hide	C22H24N4O3	1
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
CP0435369 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)urea Show/Hide	C22H25N5O3	1
1	IC50 = 45 nM Bioactivity Info	TI LI LO TS
CP0526934 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(3-cyanophenyl)urea Show/Hide	C21H22N6O	1
1	IC50 = 72 nM Bioactivity Info	TI LI LO TS
CP0378091 Compound Info	N-[(1R,3S)-3-(1H-benzimidazol-2-yl)cyclohexyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide Show/Hide	C22H23N3O3	1
1	IC50 = 88 nM Bioactivity Info	TI LI LO TS
CP0424291 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-phenylurea Show/Hide	C20H23N5O	1
1	IC50 = 103 nM Bioactivity Info	TI LI LO TS
CP0435241 Compound Info	1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-pyridin-3-ylurea Show/Hide	C19H22N6O	1
1	IC50 = 191 nM Bioactivity Info	TI LI LO TS
CP0381132 Compound Info	2-[(3R,8E,11S)-3-(4-chlorophenyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]-N-[(4-chlorophenyl)methyl]acetamide Show/Hide	C25H26Cl2N2O4	2
1	IC50 = 400 nM Bioactivity Info	TI LI LO TS
2	IC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0445334 Compound Info	2-[(3R,8E,11S)-3-benzyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]-N-[(4-chlorophenyl)methyl]acetamide Show/Hide	C26H29ClN2O4	1
1	IC50 = 4000 nM Bioactivity Info	TI LI LO TS
CP0446078 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,6S,8Z,11S)-6-methyl-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C26H29ClN2O4	1
1	IC50 = 4000 nM Bioactivity Info	TI LI LO TS
CP0446173 Compound Info	2-[(2R,6S,8E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]-N-(4,4,4-trifluorobutyl)acetamide Show/Hide	C22H27F3N2O4	1
1	IC50 = 4000 nM Bioactivity Info	TI LI LO TS
CP0381131 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,8E,11S)-3-(5-chloropyridin-2-yl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C24H25Cl2N3O4	1
1	IC50 = 4300 nM Bioactivity Info	TI LI LO TS
CP0436791 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,8E,11S)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C25H27ClN2O4	1
1	IC50 = 5000 nM Bioactivity Info	TI LI LO TS
CP0446175 Compound Info	N-[(3-chlorophenyl)methyl]-2-[(2R,6S,8E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide Show/Hide	C25H27ClN2O4	1
1	IC50 = 5000 nM Bioactivity Info	TI LI LO TS
CP0462845 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,8E,11S)-3-(4-fluorophenyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C25H26ClFN2O4	1
1	IC50 = 5000 nM Bioactivity Info	TI LI LO TS
CP0508214 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,8E,11S)-3-cyclohexyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C25H33ClN2O4	1
1	IC50 = 5000 nM Bioactivity Info	TI LI LO TS
CP0446172 Compound Info	2-[(3R,6R,8E,11S)-6-benzyl-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]-N-[(4-chlorophenyl)methyl]acetamide Show/Hide	C32H33ClN2O4	1
1	IC50 = 6000 nM Bioactivity Info	TI LI LO TS
CP0436800 Compound Info	tert-butyl 2-[(3R,8E,11S)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]acetate Show/Hide	C22H29NO5	1
1	IC50 = 7000 nM Bioactivity Info	TI LI LO TS
CP0446174 Compound Info	(2R,6S,8E)-6-[(4-chlorophenyl)methyl]-4-methyl-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione Show/Hide	C24H26ClNO3	1
1	IC50 = 8000 nM Bioactivity Info	TI LI LO TS
CP0449561 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(2R,3S,6S,8E)-3,4-dimethyl-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide Show/Hide	C27H31ClN2O4	1
1	IC50 = 8000 nM Bioactivity Info	TI LI LO TS
CP0455203 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,6S,8E,11S)-6-methyl-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C26H29ClN2O4	1
1	IC50 = 8000 nM Bioactivity Info	TI LI LO TS
CP0445333 Compound Info	2-[(3R,8E,11S)-3-butyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]-N-[(4-chlorophenyl)methyl]acetamide Show/Hide	C23H31ClN2O4	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0381127 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(2R,3S,6S)-3,4-dimethyl-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-6-yl]acetamide Show/Hide	C27H33ClN2O4	1
1	IC50 = 11000 nM Bioactivity Info	TI LI LO TS
CP0462847 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(2R,3R,6S,8E)-3-methyl-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide Show/Hide	C26H29ClN2O4	1
1	IC50 = 11000 nM Bioactivity Info	TI LI LO TS
CP0462846 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(2R,3S,6S,8E)-3-methyl-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide Show/Hide	C26H29ClN2O4	1
1	IC50 = 15000 nM Bioactivity Info	TI LI LO TS
CP0499381 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3S,5E,12S)-2,9-dioxo-10-oxa-1-azabicyclo[10.3.0]pentadec-5-en-3-yl]acetamide Show/Hide	C22H27ClN2O4	1
1	IC50 = 15000 nM Bioactivity Info	TI LI LO TS
CP0413690 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3S,8E,11S)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C25H27ClN2O4	1
1	IC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0381128 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(3R,8E,11S)-5,12-dioxo-3-propan-2-yl-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C22H29ClN2O4	1
1	IC50 = 23000 nM Bioactivity Info	TI LI LO TS
CP0096264 Compound Info	(S,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide Show/Hide	C19H23ClN2O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0381129 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(2R,6S,8E,11S)-5,12-dioxo-2-phenyl-11-(propan-2-ylamino)-1-oxa-4-azacyclododec-8-en-6-yl]acetamide Show/Hide	C28H34ClN3O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0436799 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(1S,4S,6E,12R)-3,10-dioxo-2-oxa-11-azatricyclo[10.7.0.013,18]nonadeca-6,13,15,17-tetraen-4-yl]acetamide Show/Hide	C26H27ClN2O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0462963 Compound Info	(3R,8E,11R)-11-methyl-3-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione Show/Hide	C17H21NO3	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0513271 Compound Info	N-[(4-chlorophenyl)methyl]-2-[(5E,11R)-2,9-dioxo-11-phenyl-1-oxa-3,10-diazacyclododec-5-en-3-yl]acetamide Show/Hide	C24H26ClN3O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0513286 Compound Info	[(1R)-2-[[(2S)-2-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]pent-4-enoyl]amino]-1-phenylethyl] pent-4-enoate Show/Hide	C27H31ClN2O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0534325 Compound Info	N-[(3R,8E,11R)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]acetamide Show/Hide	C18H22N2O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS
CP0534555 Compound Info	(2R,6S,8E)-6-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione Show/Hide	C23H31N3O4	1
1	IC50 > 25000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT04361, Protein smoothened

Protein Info

Protein ID: PT02715, Sonic hedgehog protein

Protein Info

Cell Viability or Cytotoxicity Assay

Compound ID	Compound Name	Compound Formula
CP0179329 Compound Info	Alphitolic acid Show/Hide	C30H48O4	1
1	IC50 = 145000 nM	TI LI LO TS
CP0461406 Compound Info	(1R,2R,5S,8R,9R,10R,13R,14R,15S,16R,18R)-15-formyl-16-hydroxy-1,2,14,17,17-pentamethyl-8-prop-1-en-2-ylpentacyclo[11.7.0.02,10.05,9.014,18]icosane-5-carboxylic acid Show/Hide	C30H46O4	1
1	IC50 = 167000 nM	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Embryo)

Cell Line Name		Organism	Disease
Bm5	Cell Line Info	Bombyx mori (Silk moth)	-
Schneider 2	Cell Line Info	Drosophila melanogaster (Fruit fly)	-
NIH 3T3	Cell Line Info	Mus musculus (Mouse)	-
BALB/3T3 clone A31	Cell Line Info	Mus musculus (Mouse)	-
NIH-3T3-G185	Cell Line Info	Mus musculus (Mouse)	-
HER14	Cell Line Info	Mus musculus (Mouse)	-
B104-1-1	Cell Line Info	Mus musculus (Mouse)	-
3T3-L1	Cell Line Info	Mus musculus (Mouse)	-
Shh Light II	Cell Line Info	Mus musculus (Mouse)	-
MEF3.8	Cell Line Info	Mus musculus (Mouse)	-
NIH 3T3-ras	Cell Line Info	Mus musculus (Mouse)	-
NIH-3T3-A14	Cell Line Info	Mus musculus (Mouse)	-
3T3/HH FlashII-7	Cell Line Info	Mus musculus (Mouse)	-
TSC1-/- MEF	Cell Line Info	Mus musculus (Mouse)	-
MEF-1 [Mouse fibroblast]	Cell Line Info	Mus musculus (Mouse)	-
Ptch-deficient MEF	Cell Line Info	Mus musculus (Mouse)	-
Rat1	Cell Line Info	Rattus norvegicus (Rat)	-
REF52	Cell Line Info	Rattus norvegicus (Rat)	-
SR-3Y1-1	Cell Line Info	Rattus norvegicus (Rat)	-
SAE	Cell Line Info	Squalus acanthias (Spiny dogfish)	-
BTI-Tn-5B1-4	Cell Line Info	Trichoplusia ni (Cabbage looper)	-

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han