General Information of the Cell Line
Cell Line ID
CL000933
Cell Line Name
Bm5
Synonyms
BM-5
Bm-5
Bm
Category
Spontaneously immortalized cell line
Organism
Bombyx mori (Silk moth)
Tissue Information
Embryo
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT06098, Ecdysone receptor
Compound ID Compound Name Compound Formula
CP0452440
CHEBI:38450
   Show/Hide
C24H30N2O3
 1
1
EC50 = 1 nM
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CP0010630
CHEBI:38452
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C22H28N2O2
 2
1
EC50 = 1.122 nM
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2
EC50 = 1.23 nM
   TI
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CP0415943
N'-tert-butyl-N'-(2-chlorobenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide
   Show/Hide
C22H25ClN2O3
 1
1
EC50 = 2.884 nM
   TI
   LI
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   TS
CP0001249
3-methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
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C22H28N2O3
 2
1
EC50 = 3.388 nM
   TI
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2
EC50 = 6.026 nM
   TI
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CP0001251
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-5-methyl-3,4-dihydro-2H-chromene-6-carboxamide
   Show/Hide
C26H31NO3
 1
1
EC50 = 4.365 nM
   TI
   LI
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   TS
CP0010026
N'-benzoyl-N'-tert-butyl-4-ethylbenzohydrazide
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C20H24N2O2
 2
1
EC50 = 4.898 nM
   TI
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2
EC50 = 17.38 nM
   TI
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CP0003493
N-tert-butyl-2-chloro-N'-(4-ethylbenzoyl)benzohydrazide
   Show/Hide
C20H23ClN2O2
 1
1
EC50 = 5.754 nM
   TI
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CP0004427
N-tert-butyl-2-chloro-N'-(4-propan-2-ylbenzoyl)benzohydrazide
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C21H25ClN2O2
 2
1
EC50 = 6.607 nM
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2
EC50 = 24.55 nM
   TI
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CP0417742
N-tert-butyl-N'-(4-tert-butylbenzoyl)-3,5-dimethylbenzohydrazide
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C24H32N2O2
 1
1
EC50 = 7.079 nM
   TI
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CP0007801
N-tert-butyl-2-chloro-N'-(4-iodobenzoyl)benzohydrazide
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C18H18ClIN2O2
 1
1
EC50 = 7.586 nM
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CP0001677
N-tert-butyl-2-chloro-N'-(4-propylbenzoyl)benzohydrazide
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C21H25ClN2O2
 2
1
EC50 = 9.12 nM
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2
EC50 = 30.9 nM
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CP0005690
N'-tert-butyl-2,3-dichloro-N'-(2-chlorobenzoyl)benzohydrazide
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C18H17Cl3N2O2
 1
1
EC50 = 9.333 nM
   TI
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CP0380205
N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-2,3-dimethylbenzohydrazide
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C22H28N2O2
 1
1
EC50 = 10.96 nM
   TI
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CP0003998
N-tert-butyl-3,5-dimethyl-N'-(4-methylbenzoyl)benzohydrazide
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C21H26N2O2
 1
1
EC50 = 12.02 nM
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CP0010025
N-tert-butyl-N'-(4-ethylbenzoyl)naphthalene-1-carbohydrazide
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C24H26N2O2
 1
1
EC50 = 13.18 nM
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CP0001248
N'-tert-butyl-N'-(2-chlorobenzoyl)-3-methoxy-2-methylbenzohydrazide
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C20H23ClN2O3
 1
1
EC50 = 15.49 nM
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CP0004607
N-tert-butyl-2-chloro-N'-(4-methylbenzoyl)benzohydrazide
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C19H21ClN2O2
 1
1
EC50 = 18.62 nM
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CP0008700
N-tert-butyl-N'-(4-chlorobenzoyl)-3,5-dimethylbenzohydrazide
   Show/Hide
C20H23ClN2O2
 1
1
EC50 = 19.05 nM
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CP0003999
N'-tert-butyl-N'-(2-chlorobenzoyl)-2,3-dimethylbenzohydrazide
   Show/Hide
C20H23ClN2O2
 1
1
EC50 = 19.95 nM
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CP0440780
N'-tert-butyl-N'-(2-chloro-3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide
   Show/Hide
C24H29ClN2O3
 1
1
EC50 = 33.11 nM
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CP0010921
N'-(4-bromobenzoyl)-N-tert-butyl-2-chlorobenzohydrazide
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C18H18BrClN2O2
 2
1
EC50 = 33.88 nM
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2
EC50 = 151.36 nM
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CP0003340
N'-tert-butyl-N'-(2-chlorobenzoyl)-2-fluorobenzohydrazide
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C18H18ClFN2O2
 2
1
EC50 = 51.29 nM
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2
EC50 = 144.54 nM
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CP0008167
N-tert-butyl-2-chloro-N'-(4-methoxybenzoyl)benzohydrazide
   Show/Hide
C19H21ClN2O3
 2
1
EC50 = 51.29 nM
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2
EC50 = 134.9 nM
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CP0005220
N-tert-butyl-2-chloro-N'-(3-methoxybenzoyl)benzohydrazide
   Show/Hide
C19H21ClN2O3
 1
1
EC50 = 52.48 nM
   TI
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CP0005689
N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-3-ethoxy-2-methylbenzohydrazide
   Show/Hide
C23H30N2O3
 1
1
EC50 = 52.48 nM
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CP0010035
N-tert-butyl-N'-(3-methoxybenzoyl)-3,5-dimethylbenzohydrazide
   Show/Hide
C21H26N2O3
 1
1
EC50 = 66.07 nM
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CP0005747
N'-benzoyl-N-tert-butyl-3,5-dimethylbenzohydrazide
   Show/Hide
C20H24N2O2
 2
1
EC50 = 69.18 nM
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2
EC50 = 199.53 nM
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CP0010644
N-tert-butyl-2-chloro-N'-(3-fluorobenzoyl)benzohydrazide
   Show/Hide
C18H18ClFN2O2
 1
1
EC50 = 69.18 nM
   TI
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CP0011651
N'-tert-butyl-N'-(2-chlorobenzoyl)-2-methylbenzohydrazide
   Show/Hide
C19H21ClN2O2
 2
1
EC50 = 72.44 nM
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2
EC50 = 128.82 nM
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CP0004027
N'-benzoyl-N-tert-butyl-2-chlorobenzohydrazide
   Show/Hide
C18H19ClN2O2
 1
1
EC50 = 75.86 nM
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CP0007594
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-4-ethylbenzamide
   Show/Hide
C24H29NO2
 1
1
EC50 = 77.62 nM
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CP0006680
CHEBI:38451
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C18H19ClN2O2
 2
1
EC50 = 77.62 nM
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2
EC50 = 87.1 nM
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CP0005379
N-tert-butyl-N'-hexanoyl-3,5-dimethylbenzohydrazide
   Show/Hide
C19H30N2O2
 1
1
EC50 = 79.43 nM
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CP0003343
N'-tert-butyl-N'-(2-chlorobenzoyl)-3,4-dimethylbenzohydrazide
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C20H23ClN2O2
 1
1
EC50 = 87.1 nM
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CP0007851
N-tert-butyl-3,5-dimethyl-N'-(4-methylpentanoyl)benzohydrazide
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C19H30N2O2
 1
1
EC50 = 91.2 nM
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CP0011383
N-tert-butyl-3,5-dimethyl-N'-octanoylbenzohydrazide
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C21H34N2O2
 1
1
EC50 = 97.72 nM
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CP0003341
N'-benzoyl-N-tert-butyl-2-iodobenzohydrazide
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C18H19IN2O2
 1
1
EC50 = 104.71 nM
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CP0005218
N-tert-butyl-2-chloro-N'-(4-chlorobenzoyl)benzohydrazide
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C18H18Cl2N2O2
 1
1
EC50 = 114.82 nM
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CP0440788
N-tert-butyl-2-chloro-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
   Show/Hide
C22H27ClN2O2
 1
1
EC50 = 114.82 nM
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CP0005961
N'-benzoyl-N-tert-butyl-2,4-dichlorobenzohydrazide
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C18H18Cl2N2O2
 1
1
EC50 = 117.49 nM
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CP0005221
N-tert-butyl-2-chloro-N'-(3-chlorobenzoyl)benzohydrazide
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C18H18Cl2N2O2
 2
1
EC50 = 154.88 nM
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2
EC50 = 309.03 nM
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CP0008166
N'-tert-butyl-N'-(2-chlorobenzoyl)-2,4-dimethylbenzohydrazide
   Show/Hide
C20H23ClN2O2
 1
1
EC50 = 162.18 nM
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CP0003497
N'-benzoyl-2-bromo-N-tert-butylbenzohydrazide
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C18H19BrN2O2
 1
1
EC50 = 169.82 nM
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CP0003496
N'-(3-bromobenzoyl)-N-tert-butyl-2-chlorobenzohydrazide
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C18H18BrClN2O2
 1
1
EC50 = 190.55 nM
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CP0012429
N-[3-(3,5-dimethylbenzoyl)pentan-3-yl]-5-methyl-3,4-dihydro-2H-chromene-6-carboxamide
   Show/Hide
C25H31NO3
 1
1
EC50 = 190.55 nM
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CP0001517
N'-benzoyl-N-tert-butyl-2-nitrobenzohydrazide
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C18H19N3O4
 1
1
EC50 = 223.87 nM
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CP0005962
N'-benzoyl-N-tert-butyl-2-methylbenzohydrazide
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C19H22N2O2
 1
1
EC50 = 223.87 nM
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CP0415944
N-tert-butyl-2-chloro-3,5-dimethyl-N'-(4-methylbenzoyl)benzohydrazide
   Show/Hide
C21H25ClN2O2
 1
1
EC50 = 302 nM
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CP0001267
N'-benzoyl-N-tert-butyl-2-fluorobenzohydrazide
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C18H19FN2O2
 1
1
EC50 = 309.03 nM
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CP0001266
N'-(2-bromobenzoyl)-N-tert-butyl-2-chlorobenzohydrazide
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C18H18BrClN2O2
 1
1
EC50 = 316.23 nM
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CP0415928
N-tert-butyl-N'-(3-fluorobenzoyl)-2-methylbenzohydrazide
   Show/Hide
C19H21FN2O2
 1
1
EC50 = 323.59 nM
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CP0011203
N'-tert-butyl-2-chloro-N'-(2-chlorobenzoyl)benzohydrazide
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C18H18Cl2N2O2
 1
1
EC50 = 331.13 nM
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CP0005219
N-tert-butyl-2-chloro-N'-(4-fluorobenzoyl)benzohydrazide
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C18H18ClFN2O2
 1
1
EC50 = 389.05 nM
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CP0001518
CHEBI:38457
   Show/Hide
C18H20N2O2
 2
1
EC50 = 426.58 nM
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2
EC50 = 436.52 nM
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CP0452436
N-tert-butyl-2-chloro-N'-(4-pentylbenzoyl)benzohydrazide
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C23H29ClN2O2
 1
1
EC50 = 426.58 nM
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CP0415945
N-tert-butyl-2-chloro-N'-(4-chlorobenzoyl)-3,5-dimethylbenzohydrazide
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C20H22Cl2N2O2
 1
1
EC50 = 446.68 nM
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CP0008675
N'-benzoyl-N-tert-butyl-2-methoxybenzohydrazide
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C19H22N2O3
 1
1
EC50 = 524.81 nM
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CP0007785
N'-benzoyl-N-tert-butyl-2-ethylbenzohydrazide
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C20H24N2O2
 1
1
EC50 = 588.84 nM
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CP0003339
N-tert-butyl-2-chloro-N'-(3-methylbenzoyl)benzohydrazide
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C19H21ClN2O2
 1
1
EC50 = 602.56 nM
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CP0003355
N-tert-butyl-2-chloro-N'-(4-cyanobenzoyl)benzohydrazide
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C19H18ClN3O2
 1
1
EC50 = 602.56 nM
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CP0008676
N'-benzoyl-N-tert-butyl-2-(trifluoromethyl)benzohydrazide
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C19H19F3N2O2
 2
1
EC50 = 630.96 nM
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2
EC50 = 870.96 nM
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CP0007772
N-tert-butyl-2-chloro-N'-heptanoylbenzohydrazide
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C18H27ClN2O2
 1
1
EC50 = 741.31 nM
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CP0011247
N'-tert-butyl-4-ethyl-N'-(4-methylpentanoyl)benzohydrazide
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C19H30N2O2
 1
1
EC50 = 831.76 nM
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CP0005116
N'-benzoyl-N'-cyclohexylbenzohydrazide
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C20H22N2O2
 1
1
EC50 = 891.25 nM
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CP0003495
N-tert-butyl-2-chloro-N'-(3-cyanobenzoyl)benzohydrazide
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C19H18ClN3O2
 1
1
EC50 = 954.99 nM
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CP0008440
N'-tert-butyl-N'-(cyclohex-3-ene-1-carbonyl)-4-ethylbenzohydrazide
   Show/Hide
C20H28N2O2
 1
1
EC50 = 1000 nM
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CP0417744
N-tert-butyl-N'-(4-butylbenzoyl)-2-chloro-3,5-dimethylbenzohydrazide
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C24H31ClN2O2
 1
1
EC50 = 1148.15 nM
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CP0007773
N'-benzoyl-N-tert-butyl-2-chloro-3,5-dimethylbenzohydrazide
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C20H23ClN2O2
 1
1
EC50 = 1174.9 nM
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CP0391250
N-tert-butyl-2-chloro-N'-(4-methoxybenzoyl)-3,5-dimethylbenzohydrazide
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C21H25ClN2O3
 1
1
EC50 = 1230.27 nM
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CP0005748
N-[3-(3,5-dimethylbenzoyl)pentan-3-yl]-4-ethylbenzamide
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C23H29NO2
 1
1
EC50 = 1258.93 nM
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CP0001265
N-tert-butyl-2-chloro-N'-(2-iodobenzoyl)benzohydrazide
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C18H18ClIN2O2
 1
1
EC50 = 1288.25 nM
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CP0011578
N-tert-butyl-N'-decanoyl-3,5-dimethylbenzohydrazide
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C23H38N2O2
 1
1
EC50 = 1548.82 nM
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CP0007387
N'-tert-butyl-N'-(2-chlorobenzoyl)-2,5-dimethylbenzohydrazide
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C20H23ClN2O2
 1
1
EC50 = 1621.81 nM
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CP0003996
N'-benzoyl-N'-(cyclohexylmethyl)benzohydrazide
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C21H24N2O2
 1
1
EC50 = 1698.24 nM
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CP0442306
N-tert-butyl-2-chloro-3,5-dimethyl-N'-(4-pentylbenzoyl)benzohydrazide
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C25H33ClN2O2
 1
1
EC50 = 1778.28 nM
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CP0010028
N-tert-butyl-3,5-dimethyl-N'-pentanoylbenzohydrazide
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C18H28N2O2
 1
1
EC50 = 1862.09 nM
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CP0010029
N'-tert-butyl-4-ethyl-N'-hexanoylbenzohydrazide
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C19H30N2O2
 1
1
EC50 = 2818.38 nM
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CP0001247
N'-benzoyl-N'-(2-methylpropyl)benzohydrazide
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C18H20N2O2
 1
1
EC50 = 2884.03 nM
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CP0005378
N-tert-butyl-2-ethoxy-N'-(4-ethylbenzoyl)benzohydrazide
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C22H28N2O3
 1
1
EC50 = 2884.03 nM
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CP0452439
N'-benzoyl-N-tert-butyl-2,3,4-trichlorobenzohydrazide
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C18H17Cl3N2O2
 1
1
EC50 = 3630.78 nM
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CP0003342
N'-benzoyl-N'-butylbenzohydrazide
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C18H20N2O2
 1
1
EC50 = 7079.46 nM
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CP0006679
N'-tert-butyl-N'-heptanoylbenzohydrazide
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C18H28N2O2
 1
1
EC50 = 7244.36 nM
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CP0460465
N-tert-butyl-N'-(4-chlorobenzoyl)-2-ethoxybenzohydrazide
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C20H23ClN2O3
 1
1
EC50 = 7762.47 nM
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CP0013496
N'-tert-butyl-N'-hexanoyl-3,5-dimethylbenzohydrazide
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C19H30N2O2
 1
1
EC50 = 8709.64 nM
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CP0001264
N'-tert-butyl-N'-(cyclohexanecarbonyl)-4-ethylbenzohydrazide
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C20H30N2O2
 1
1
EC50 = 9332.54 nM
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CP0010920
N'-tert-butyl-4-ethyl-N'-heptanoylbenzohydrazide
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C20H32N2O2
 1
1
EC50 = 11748.98 nM
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CP0010643
N'-tert-butyl-3,5-dimethyl-N'-(4-methylpentanoyl)benzohydrazide
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C19H30N2O2
 1
1
EC50 = 14454.4 nM
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CP0415942
N-tert-butyl-N'-(4-butylbenzoyl)-2-ethoxybenzohydrazide
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C24H32N2O3
 1
1
EC50 = 16218.1 nM
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CP0417741
N-tert-butyl-2-ethoxy-N'-(4-methoxybenzoyl)benzohydrazide
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C21H26N2O4
 1
1
EC50 = 19054.61 nM
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CP0007850
N'-benzoyl-N'-phenylbenzohydrazide
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C20H16N2O2
 1
1
EC50 = 25703.96 nM
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CP0007383
N-[1-(3,5-dimethylphenyl)-3,3-dimethyl-1-oxobutan-2-yl]-4-ethylbenzamide
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C23H29NO2
 2
1
EC50 = 35481.34 nM
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2
IC50 = 28183.83 nM
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CP0008441
N'-tert-butyl-N'-(cyclohexanecarbonyl)benzohydrazide
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C18H26N2O2
 1
1
EC50 = 46773.51 nM
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CP0004753
(4-chlorophenyl)-[6-fluoro-4-(4-fluoroanilino)-2-methyl-3,4-dihydro-2H-quinolin-1-yl]methanone
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C23H19ClF2N2O
 2
1
EC50 = 54954.09 nM
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2
EC50 = 55000 nM
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CP0004437
N'-benzoyl-N-butyl-N'-tert-butylbenzohydrazide
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C22H28N2O2
 1
1
EC50 > 100000 nM
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CP0010642
N'-benzoyl-N'-methylbenzohydrazide
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C15H14N2O2
 1
1
EC50 > 100000 nM
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CP0011202
N'-tert-butyl-3,5-dimethyl-N'-(5-methylhexanoyl)benzohydrazide
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C20H32N2O2
 1
1
EC50 > 100000 nM
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CP0011653
N'-benzoyl-N,N'-dimethylbenzohydrazide
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C16H16N2O2
 1
1
EC50 > 100000 nM
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CP0007786
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-2,2,2-trifluoroacetamide
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C17H20F3NO2
 2
1
EC50 < 100000 nM
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2
IC50 = 67608.3 nM
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CP0008229
(4-chlorophenyl)-[4-(4-methylanilino)piperidin-1-yl]methanone
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C19H21ClN2O
 1
1
IC50 = 2238.72 nM
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CP0010309
(4-chlorophenyl)-[4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]methanone
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C23H21ClN2O
 1
1
IC50 = 8912.51 nM
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CP0011590
4-chloro-N-[1-(4-chlorobenzoyl)-2,6-dimethyl-3,4-dihydro-2H-quinolin-4-yl]-N-(4-methylphenyl)benzamide
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C32H28Cl2N2O2
 1
1
IC50 = 13489.63 nM
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CP0007800
(4-chlorophenyl)-[2,6-dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]methanone
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C25H25ClN2O
 1
1
IC50 = 14791.08 nM
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CP0011652
(4-tert-butylphenyl)-[2,6-dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]methanone
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C29H34N2O
 1
1
IC50 = 23988.33 nM
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CP0003997
[2,6-dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone
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C26H28N2O
 1
1
IC50 = 26915.35 nM
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CP0012428
(4-chlorophenyl)-(2-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
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C17H16ClNO
 1
1
IC50 = 47863.01 nM
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Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0007383
N-[1-(3,5-dimethylphenyl)-3,3-dimethyl-1-oxobutan-2-yl]-4-ethylbenzamide
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C23H29NO2  1
1
LC50 = 38904.51 nM
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CP0007786
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-2,2,2-trifluoroacetamide
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C17H20F3NO2  1
1
LC50 = 234422.88 nM
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CP0007800
(4-chlorophenyl)-[2,6-dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]methanone
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C25H25ClN2O  1
1
LC50 = 34673.69 nM
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CP0010309
(4-chlorophenyl)-[4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]methanone
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C23H21ClN2O  1
1
LC50 = 21379.62 nM
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CP0011590
4-chloro-N-[1-(4-chlorobenzoyl)-2,6-dimethyl-3,4-dihydro-2H-quinolin-4-yl]-N-(4-methylphenyl)benzamide
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C32H28Cl2N2O2  1
1
LC50 = 7079.46 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Embryo)
Cell Line Name Organism Disease
Schneider 2 Drosophila melanogaster (Fruit fly) -
NIH 3T3 Mus musculus (Mouse) -
BALB/3T3 clone A31 Mus musculus (Mouse) -
NIH-3T3-G185 Mus musculus (Mouse) -
HER14 Mus musculus (Mouse) -
B104-1-1 Mus musculus (Mouse) -
3T3-L1 Mus musculus (Mouse) -
C3H/10T1/2 clone 8 Mus musculus (Mouse) -
Shh Light II Mus musculus (Mouse) -
MEF3.8 Mus musculus (Mouse) -
NIH 3T3-ras Mus musculus (Mouse) -
NIH-3T3-A14 Mus musculus (Mouse) -
3T3/HH FlashII-7 Mus musculus (Mouse) -
TSC1-/- MEF Mus musculus (Mouse) -
MEF-1 [Mouse fibroblast] Mus musculus (Mouse) -
Ptch-deficient MEF Mus musculus (Mouse) -
Rat1 Rattus norvegicus (Rat) -
REF52 Rattus norvegicus (Rat) -
SR-3Y1-1 Rattus norvegicus (Rat) -
SAE Squalus acanthias (Spiny dogfish) -
BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper) -