General Information of the Cell Line
Cell Line ID
CL000090
Cell Line Name
Schneider 2
Synonyms
S2
S-2
SC-2
SL-2
SL2
Line 2
Schneider's Line S2
Schneider's line 2
Schneider Line 2
Schneider L2
Schneider's Drosophila Line2
SCHNEIDER-2
SCHNEIDER S2
Schneider S2
Drosophila Line 2
D. mel. (2)
D.Mel-2
D.mel-2
WR69-DM-2
WR-DM-2
Dm2
DL2
S2-ATCC
S2-Invitrogen
S2-RIKEN
S2U
Category
Spontaneously immortalized cell line
Organism
Drosophila melanogaster (Fruit fly)
Cellosaurus ID
CVCL_Z232
Tissue Information
Embryo
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01020, Beta-secretase 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0556169
 Compound Info 
US10336717, Compound 178
   Show/Hide
C24H25ClFN3O2
  1
1
IC50 = 0.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0479216
 Compound Info 
US10336717, Compound 193
   Show/Hide
C25H25ClN4O2
  1
1
IC50 = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0479215
 Compound Info 
US10336717, Compound 192
   Show/Hide
C25H25FN4O2
  1
1
IC50 = 0.96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0518242
 Compound Info 
US10336717, Compound 183
   Show/Hide
C24H25F2N3O2
  1
1
IC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419477
 Compound Info 
US10336717, Compound 463
   Show/Hide
C25H22ClFN4O2
  1
1
IC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465547
 Compound Info 
US9212153, 180,Ex. 141
   Show/Hide
C26H25N5O2
  1
1
IC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402580
 Compound Info 
US9212153, 394,Ex. 335
   Show/Hide
C27H26N4O
  1
1
IC50 = 1.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556171
 Compound Info 
US10336717, Compound 188
   Show/Hide
C23H25FN4O2
  1
1
IC50 = 1.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0518240
 Compound Info 
US10336717, Compound 142
   Show/Hide
C29H31N3O2
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0360149
 Compound Info 
US10336717, Compound 76
   Show/Hide
C23H27N3O2
  1
1
IC50 = 2.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442491
 Compound Info 
US9212153, 147,Ex. 111
   Show/Hide
C25H31N3O2
  1
1
IC50 = 2.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0563832
 Compound Info 
US10336717, Compound 478
   Show/Hide
C23H27N3O2
  1
1
IC50 = 2.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442918
 Compound Info 
US10336717, Compound 99
   Show/Hide
C22H25F2N3O2
  1
1
IC50 = 2.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0171911
 Compound Info 
US8633212, 1
   Show/Hide
C23H25ClFN3O2
  1
1
IC50 = 2.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0479214
 Compound Info 
US10336717, Compound 187
   Show/Hide
C23H25ClN4O2
  1
1
IC50 = 2.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578226
 Compound Info 
US10336717, Compound 179
   Show/Hide
C25H25FN4O2
  1
1
IC50 = 2.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516831
 Compound Info 
US9212153, 467,Ex. 401
   Show/Hide
C24H24N4O2
  1
1
IC50 = 2.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527345
 Compound Info 
US10336717, Compound 185
   Show/Hide
C24H25F3N4O2
  1
1
IC50 = 2.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465548
 Compound Info 
US10336717, Compound 189
   Show/Hide
C23H25FN4O2
  1
1
IC50 = 2.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556170
 Compound Info 
US9212153, 184,Ex. 145
   Show/Hide
C23H26N4O2
  1
1
IC50 = 3.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384892
 Compound Info 
US8633212, 2
   Show/Hide
C24H25ClN4O2
  1
1
IC50 = 3.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504097
 Compound Info 
US10336717, Compound 115
   Show/Hide
C20H22F3N3O2
  1
1
IC50 = 3.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384893
 Compound Info 
US9212153, 4
   Show/Hide
C26H27N3O2
  1
1
IC50 = 4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0351727
 Compound Info 
US8633212, 5
   Show/Hide
C23H26ClN3O2
  1
1
IC50 = 4.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423313
 Compound Info 
US9212153, 3
   Show/Hide
C23H28N2O2
  1
1
IC50 = 4.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516220
 Compound Info 
US9212153, 100,Ex. 66
   Show/Hide
C24H24F2N4O2
  1
1
IC50 = 4.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0171913
 Compound Info 
US8633212, 6
   Show/Hide
C23H25Cl2N3O2
  1
1
IC50 = 4.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442495
 Compound Info 
US9212153, 205,Ex. 165
   Show/Hide
C21H22F3N3O2
  1
1
IC50 = 4.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0506847
 Compound Info 
US9212153, 106,Ex. 72
   Show/Hide
C26H26N4O
  1
1
IC50 = 5.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0321888
 Compound Info 
US8633212, 8
   Show/Hide
C24H25FN4O2
  1
1
IC50 = 5.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0365336
 Compound Info 
US8633212, 7
   Show/Hide
C24H28ClN3O3
  1
1
IC50 = 5.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560164
 Compound Info 
US10336717, Compound 468
   Show/Hide
C18H19BrN4O2
  1
1
IC50 = 6.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418189
 Compound Info 
US9212153, 395,Ex. 336
   Show/Hide
C27H25FN4O
  1
1
IC50 = 6.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0365337
 Compound Info 
US8633212, 9
   Show/Hide
C24H26F3N3O3
  1
1
IC50 = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419948
 Compound Info 
US10336717, Compound 452
   Show/Hide
C23H22ClN5O2
  1
1
IC50 = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0413464
 Compound Info 
US10336717, Compound 135
   Show/Hide
C26H28N4O2
  1
1
IC50 = 7.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450012
 Compound Info 
US10336717, Compound 10
   Show/Hide
C28H25ClN4O
  1
1
IC50 = 7.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436119
 Compound Info 
US9212153, 11
   Show/Hide
C26H27F3N2O3
  1
1
IC50 = 7.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236600
 Compound Info 
US8633212, 12
   Show/Hide
C24H25FN4O2
  1
1
IC50 = 7.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0517880
 Compound Info 
US9212153, 464,Ex. 398
   Show/Hide
C24H23N5O2
  1
1
IC50 = 7.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556398
 Compound Info 
US9212153, 146,Ex. 110
   Show/Hide
C24H31N3O2
  1
1
IC50 = 7.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0443054
 Compound Info 
US10336717, Compound 136
   Show/Hide
C25H28ClN3O2
  1
1
IC50 = 8.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442482
 Compound Info 
US9212153, 105,Ex. 71
   Show/Hide
C26H27N3O
  1
1
IC50 = 8.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0469800
 Compound Info 
US10336717, Compound 450
   Show/Hide
C25H23N5O2
  1
1
IC50 = 8.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0526513
 Compound Info 
US8633212, 13
   Show/Hide
C23H25ClFN3O2
  1
1
IC50 = 8.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441087
 Compound Info 
US10336717, Compound 163
   Show/Hide
C25H29ClN4O2
  1
1
IC50 = 8.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442486
 Compound Info 
US9212153, 118,Ex. 84
   Show/Hide
C20H26F3N3O2
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442484
 Compound Info 
US10336717, Compound 114
   Show/Hide
C24H31N3O2
  1
1
IC50 = 9.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441073
 Compound Info 
US9212153, 14
   Show/Hide
C25H26ClFN2O2
  1
1
IC50 = 11.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236601
 Compound Info 
US10336717, Compound 15
   Show/Hide
C27H25ClFN3O
  1
1
IC50 = 11.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441074
 Compound Info 
US9212153, 16
   Show/Hide
C26H29ClN2O3
  1
1
IC50 = 11.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465550
 Compound Info 
US10336717, Compound 196
   Show/Hide
C21H24N4O2S
  1
1
IC50 = 11.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450575
 Compound Info 
US9212153, 227,Ex. 184
   Show/Hide
C27H28N4O2
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0563707
 Compound Info 
US10336717, Compound 17
   Show/Hide
C27H26ClN3O
  1
1
IC50 = 12.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0500457
 Compound Info 
US10336717, Compound 155
   Show/Hide
C26H29F3N4O2
  1
1
IC50 = 12.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419478
 Compound Info 
US10336717, Compound 466
   Show/Hide
C24H22ClN5O2
  1
1
IC50 = 13.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436145
 Compound Info 
US9212153, 139,Ex. 104
   Show/Hide
C29H30N4O2
  1
1
IC50 = 13.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0443053
 Compound Info 
US9212153, 134,Ex. 99
   Show/Hide
C19H24BrN3O2
  1
1
IC50 = 14.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0365330
 Compound Info 
US8633212, 19
   Show/Hide
C25H31N3O2
  1
1
IC50 = 14.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0412487
 Compound Info 
US10336717, Compound 110
   Show/Hide
C21H29N3O3
  1
1
IC50 = 14.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577908
 Compound Info 
US10336717, Compound 102
   Show/Hide
C26H23ClFN3O2
  1
1
IC50 = 14.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0438883
 Compound Info 
US9212153, 138,Ex. 103
   Show/Hide
C24H29N3O2
  1
1
IC50 = 15.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450026
 Compound Info 
US9212153, 145,Ex. 109
   Show/Hide
C26H27N3O2
  1
1
IC50 = 16.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0559375
 Compound Info 
US10336717, Compound 464
   Show/Hide
C19H19BrN4O2
  1
1
IC50 = 16.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578670
 Compound Info 
US9212153, 468,Ex. 402
   Show/Hide
C23H24N4O2
  1
1
IC50 = 16.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384894
 Compound Info 
US10336717, Compound 18
   Show/Hide
C22H26N4O2
  1
1
IC50 = 16.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465549
 Compound Info 
US10336717, Compound 194
   Show/Hide
C24H25N3O2S
  1
1
IC50 = 17.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0516221
 Compound Info 
US10336717, Compound 117
   Show/Hide
C22H31N3O2
  1
1
IC50 = 17.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504092
 Compound Info 
US8633212, 20
   Show/Hide
C24H26F3N3O2
  1
1
IC50 = 18.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0545609
 Compound Info 
US10336717, Compound 21
   Show/Hide
C27H25Cl2N3O
  1
1
IC50 = 18.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0284216
 Compound Info 
US10336717, Compound 22
   Show/Hide
C28H26N4O
  1
1
IC50 = 19.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0438886
 Compound Info 
US10336717, Compound 225
   Show/Hide
C25H29N3O2
  1
1
IC50 = 20 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0561359
 Compound Info 
US10336717, Compound 23
   Show/Hide
C27H25ClFN3O
  1
1
IC50 = 20.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0479207
 Compound Info 
US10336717, Compound 24
   Show/Hide
C23H29N3O2
  1
1
IC50 = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578595
 Compound Info 
US10336717, Compound 109
   Show/Hide
C21H25N5O2
  1
1
IC50 = 23.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436142
 Compound Info 
US10336717, Compound 113
   Show/Hide
C23H31N3O2
  1
1
IC50 = 24.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0365331
 Compound Info 
US8633212, 25
   Show/Hide
C24H26N4O2
  1
1
IC50 = 26.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0559766
 Compound Info 
US10336717, Compound 474
   Show/Hide
C25H29N3O3
  1
1
IC50 = 26.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0566276
 Compound Info 
US9212153, 96,Ex. 63
   Show/Hide
C23H24N4O2
  1
1
IC50 = 28.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0484865
 Compound Info 
US9212153, 264,Ex. 217
   Show/Hide
C22H25N3O2
  1
1
IC50 = 29.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0519028
 Compound Info 
US9212153, 197,Ex. 158
   Show/Hide
C22H25N5O2
  1
1
IC50 = 29.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450027
 Compound Info 
US10336717, Compound 154
   Show/Hide
C27H30N4O2
  1
1
IC50 = 30.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556404
 Compound Info 
US10336717, Compound 205
   Show/Hide
C18H22BrN3O2
  1
1
IC50 = 30.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423281
 Compound Info 
US10336717, Compound 217
   Show/Hide
C18H22BrN3O2
  1
1
IC50 = 32.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0563831
 Compound Info 
US10336717, Compound 476
   Show/Hide
C23H29N3O3
  1
1
IC50 = 33.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0518241
 Compound Info 
US9212153, 153,Ex. 116
   Show/Hide
C26H30ClN3O2
  1
1
IC50 = 36.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556405
 Compound Info 
US9212153, 229,Ex. 186
   Show/Hide
C26H31N3O2
  1
1
IC50 = 37.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0506845
 Compound Info 
US10336717, Compound 27
   Show/Hide
C28H28ClN3O2
  1
1
IC50 = 38.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0329224
 Compound Info 
US10336717, Compound 28
   Show/Hide
C25H28N4O2
  1
1
IC50 = 41.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0413457
 Compound Info 
US9212153, 49
   Show/Hide
C25H27FN4O2
  1
1
IC50 = 41.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0443052
 Compound Info 
US9212153, 122,Ex. 87
   Show/Hide
C25H25N5O
  1
1
IC50 = 42.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0442928
 Compound Info 
US10336717, Compound 195
   Show/Hide
C25H31N3O3
  1
1
IC50 = 49.7 nM
 Bioactivity Info 
   TI
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CP0442488
 Compound Info 
US10336717, Compound 121
   Show/Hide
C25H25N5O
  1
1
IC50 = 56.2 nM
 Bioactivity Info 
   TI
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CP0500455
 Compound Info 
US10336717, Compound 101
   Show/Hide
C21H28F3N3O3
  1
1
IC50 = 56.7 nM
 Bioactivity Info 
   TI
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CP0479213
 Compound Info 
US10336717, Compound 182
   Show/Hide
C24H25Cl2N3O2
  1
1
IC50 = 57.1 nM
 Bioactivity Info 
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CP0557068
 Compound Info 
US9212153, 451,Ex. 386
   Show/Hide
C23H23N5O2
  1
1
IC50 = 58.6 nM
 Bioactivity Info 
   TI
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CP0329227
 Compound Info 
US10336717, Compound 30
   Show/Hide
C21H22ClN3O
  1
1
IC50 = 61.6 nM
 Bioactivity Info 
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CP0559376
 Compound Info 
US10336717, Compound 470
   Show/Hide
C25H25ClFN5O
  1
1
IC50 = 67 nM
 Bioactivity Info 
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CP0360204
 Compound Info 
US8633212, 32
   Show/Hide
C24H28FN3O2
  1
1
IC50 = 74.1 nM
 Bioactivity Info 
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CP0450014
 Compound Info 
US10336717, Compound 116
   Show/Hide
C20H24N4O2S
  1
1
IC50 = 76.7 nM
 Bioactivity Info 
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CP0529186
 Compound Info 
US10336717, Compound 112
   Show/Hide
C25H27N3O2
  1
1
IC50 = 80.4 nM
 Bioactivity Info 
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CP0365332
 Compound Info 
US10336717, Compound 33
   Show/Hide
C27H22F2N4O
  1
1
IC50 = 89 nM
 Bioactivity Info 
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CP0423314
 Compound Info 
US10336717, Compound 34
   Show/Hide
C23H21FN4O
  1
1
IC50 = 93.3 nM
 Bioactivity Info 
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CP0521628
 Compound Info 
US9212153, 191,Ex. 152
   Show/Hide
C21H27N3O2
  1
1
IC50 = 101.7 nM
 Bioactivity Info 
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CP0188992
 Compound Info 
US10336717, Compound 35
   Show/Hide
C21H23N3O
  1
1
IC50 = 104.6 nM
 Bioactivity Info 
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CP0360197
 Compound Info 
US10336717, Compound 36
   Show/Hide
C27H24N4O2
  1
1
IC50 = 121.7 nM
 Bioactivity Info 
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CP0329228
 Compound Info 
US10336717, Compound 37
   Show/Hide
C25H28N4O2
  1
1
IC50 = 125.6 nM
 Bioactivity Info 
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CP0516830
 Compound Info 
US10336717, Compound 454
   Show/Hide
C24H27N3O
  1
1
IC50 = 128.3 nM
 Bioactivity Info 
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CP0188166
 Compound Info 
US10336717, Compound 38
   Show/Hide
C28H26F3N3O2
  1
1
IC50 = 130.4 nM
 Bioactivity Info 
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CP0442917
 Compound Info 
US10336717, Compound 108
   Show/Hide
C17H22BrN3O2
  1
1
IC50 = 136.8 nM
 Bioactivity Info 
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CP0442483
 Compound Info 
US9212153, 108,Ex. 74
   Show/Hide
C21H25N5O2
  1
1
IC50 = 156.3 nM
 Bioactivity Info 
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CP0423315
 Compound Info 
US10336717, Compound 39
   Show/Hide
C28H26F3N3O
  1
1
IC50 = 157.6 nM
 Bioactivity Info 
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CP0329229
 Compound Info 
US10336717, Compound 40
   Show/Hide
C26H22N4O
  1
1
IC50 = 159.6 nM
 Bioactivity Info 
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CP0479217
 Compound Info 
US9212153, 218,Ex. 176
   Show/Hide
C18H23N3O2
  1
1
IC50 = 161 nM
 Bioactivity Info 
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CP0188993
 Compound Info 
US10336717, Compound 41
   Show/Hide
C25H26N4O
  1
1
IC50 = 161.1 nM
 Bioactivity Info 
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CP0360153
 Compound Info 
US10336717, Compound 42
   Show/Hide
C25H27ClFN3O2
  1
1
IC50 = 172.7 nM
 Bioactivity Info 
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CP0443045
 Compound Info 
US10336717, Compound 43
   Show/Hide
C27H23FN4O
  1
1
IC50 = 178.4 nM
 Bioactivity Info 
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CP0371391
 Compound Info 
US10336717, Compound 44
   Show/Hide
C23H22F2N4O
  1
1
IC50 = 189.1 nM
 Bioactivity Info 
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CP0423316
 Compound Info 
US9212153, 45
   Show/Hide
C28H25N3O
  1
1
IC50 = 194.7 nM
 Bioactivity Info 
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CP0506848
 Compound Info 
US10336717, Compound 111
   Show/Hide
C22H27N5O3
  1
1
IC50 = 195.7 nM
 Bioactivity Info 
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CP0578227
 Compound Info 
US10336717, Compound 181
   Show/Hide
C25H25F4N3O2
  1
1
IC50 = 198.3 nM
 Bioactivity Info 
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CP0549777
 Compound Info 
US10336717, Compound 451
   Show/Hide
C18H19BrN4O2
  1
1
IC50 = 206.8 nM
 Bioactivity Info 
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CP0478822
 Compound Info 
US9212153, 94,Ex. 61
   Show/Hide
C23H24N4O
  1
1
IC50 = 222.2 nM
 Bioactivity Info 
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CP0412486
 Compound Info 
US10336717, Compound 107
   Show/Hide
C21H25N5O2
  1
1
IC50 = 228.1 nM
 Bioactivity Info 
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CP0561279
 Compound Info 
US9212153, 104,Ex. 70
   Show/Hide
C22H25N3O
  1
1
IC50 = 255.1 nM
 Bioactivity Info 
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CP0556394
 Compound Info 
US9212153, 46
   Show/Hide
C29H27N3O
  1
1
IC50 = 292.9 nM
 Bioactivity Info 
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CP0442496
 Compound Info 
US10336717, Compound 226
   Show/Hide
C20H24BrN3O2
  1
1
IC50 = 350.6 nM
 Bioactivity Info 
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CP0441075
 Compound Info 
US10336717, Compound 48
   Show/Hide
C27H22F2N4O
  1
1
IC50 = 378.3 nM
 Bioactivity Info 
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CP0236578
 Compound Info 
US10336717, Compound 82
   Show/Hide
C25H28N4O2
  1
1
IC50 = 432.3 nM
 Bioactivity Info 
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CP0469966
 Compound Info 
US10336717, Compound 50
   Show/Hide
C22H22N4O
  1
1
IC50 = 443.2 nM
 Bioactivity Info 
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CP0360147
 Compound Info 
US10336717, Compound 51
   Show/Hide
C22H22N4O2
  1
1
IC50 = 465.8 nM
 Bioactivity Info 
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CP0469968
 Compound Info 
US9212153, 249,Ex. 202
   Show/Hide
C18H22FN3O2
  1
1
IC50 = 493 nM
 Bioactivity Info 
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CP0188994
 Compound Info 
US10336717, Compound 52
   Show/Hide
C25H28N4O2
  1
1
IC50 = 505.8 nM
 Bioactivity Info 
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CP0479208
 Compound Info 
US9212153, 54
   Show/Hide
C29H28N4O
  1
1
IC50 = 617.9 nM
 Bioactivity Info 
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CP0346650
 Compound Info 
US10336717, Compound 55
   Show/Hide
C24H29N3O2
  1
1
IC50 = 670.4 nM
 Bioactivity Info 
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CP0559373
 Compound Info 
US9212153, 459,Ex. 393
   Show/Hide
C22H22N4O3S
  1
1
IC50 = 693.3 nM
 Bioactivity Info 
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CP0517882
 Compound Info 
US10336717, Compound 477
   Show/Hide
C23H27N3O2
  1
1
IC50 = 693.5 nM
 Bioactivity Info 
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CP0516833
 Compound Info 
US10336717, Compound 471
   Show/Hide
C25H20N6O
  1
1
IC50 = 869.5 nM
 Bioactivity Info 
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CP0559765
 Compound Info 
US10336717, Compound 456
   Show/Hide
C26H24N6O
  1
1
IC50 = 877.2 nM
 Bioactivity Info 
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CP0329230
 Compound Info 
US10336717, Compound 58
   Show/Hide
C26H28N4O2
  1
1
IC50 = 969.7 nM
 Bioactivity Info 
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CP0559372
 Compound Info 
US10336717, Compound 583
   Show/Hide
C22H23F2N3O3
  1
1
IC50 = 1351.28 nM
 Bioactivity Info 
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CP0516832
 Compound Info 
US10336717, Compound 469
   Show/Hide
C19H22BrN5O
  1
1
IC50 = 1519.7 nM
 Bioactivity Info 
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CP0284314
 Compound Info 
US10336717, Compound 59
   Show/Hide
C24H28N4O2
  1
1
IC50 = 1554.9 nM
 Bioactivity Info 
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CP0346651
 Compound Info 
US10336717, Compound 60
   Show/Hide
C27H24N4O
  1
1
IC50 = 1856.1 nM
 Bioactivity Info 
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CP0469801
 Compound Info 
US10336717, Compound 455
   Show/Hide
C24H20N6O
  1
1
IC50 = 2456.1 nM
 Bioactivity Info 
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CP0479210
 Compound Info 
US10336717, Compound 61
   Show/Hide
C30H24N4O
  1
1
IC50 = 3262.1 nM
 Bioactivity Info 
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CP0567354
 Compound Info 
US9212153, 458,Ex. 392
   Show/Hide
C26H27N5O2
  1
1
IC50 = 3702.8 nM
 Bioactivity Info 
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CP0574702
 Compound Info 
US10336717, Compound 446
   Show/Hide
C19H23BrF3N3O
  1
1
IC50 = 4327 nM
 Bioactivity Info 
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CP0321887
 Compound Info 
US10336717, Compound 69
   Show/Hide
C22H22N4O2
  1
1
IC50 = 4702.2 nM
 Bioactivity Info 
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CP0550186
 Compound Info 
US9212153, 63
   Show/Hide
C30H29N3O
  1
1
IC50 = 5053.9 nM
 Bioactivity Info 
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CP0517902
 Compound Info 
US10336717, Compound 475
   Show/Hide
C17H23N3O3
  1
1
IC50 = 5158 nM
 Bioactivity Info 
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CP0574703
 Compound Info 
US10336717, Compound 460
   Show/Hide
C19H18BrN3O
  1
1
IC50 = 9805.4 nM
 Bioactivity Info 
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CP0284121
 Compound Info 
US10336717, Compound 64
   Show/Hide
C19H24BrN3O2
  1
1
IC50 = 36244.8 nM
 Bioactivity Info 
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CP0479211
 Compound Info 
US10336717, Compound 65
   Show/Hide
C26H28N4O2
  1
1
IC50 = 50000 nM
 Bioactivity Info 
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Protein ID: PT01387, Dibasic-processing enzyme
 Protein Info 
Protein ID: PT00907, Dipeptidyl peptidase 4
 Protein Info 
Protein ID: PT00632, Ecdysone receptor
 Protein Info 
Protein ID: PT02647, Glutamate carboxypeptidase 2
 Protein Info 
Protein ID: PT00285, Histone deacetylase
 Protein Info 
Protein ID: PT05333, Meprin A subunit alpha
 Protein Info 
Protein ID: PT06793, Neuroendocrine convertase 1
 Protein Info 
Protein ID: PT06957, Neuroendocrine convertase 2
 Protein Info 
Protein ID: PT02663, Nuclear receptor ROR-gamma
 Protein Info 
Protein ID: PT05439, Nuclear receptor ROR-gamma
 Protein Info 
Protein ID: PT02209, Organic anion transporter 3
 Protein Info 
Protein ID: PT01241, Prolyl endopeptidase FAP
 Protein Info 
Protein ID: PT04219, Proprotein convertase subtilisin/kexin type 5
 Protein Info 
Protein ID: PT04551, Proprotein convertase subtilisin/kexin type 6
 Protein Info 
Protein ID: PT03149, Proprotein convertase subtilisin/kexin type 7
 Protein Info 
Protein ID: PT00822, Prothrombin
 Protein Info 
Protein ID: PT00845, RAC-alpha serine/threonine-protein kinase
 Protein Info 
Protein ID: PT01131, RAC-beta serine/threonine-protein kinase
 Protein Info 
Protein ID: PT03005, Serine protease hepsin
 Protein Info 
Protein ID: PT02208, Solute carrier family 22 member 11
 Protein Info 
Protein ID: PT04064, Solute carrier family 22 member 6
 Protein Info 
Protein ID: PT01847, Suppressor of tumorigenicity 14 protein
 Protein Info 
Protein ID: PT02546, Toll-like receptor 8
 Protein Info 
Protein ID: PT02691, Transmembrane protease serine 11D
 Protein Info 
Protein ID: PT03634, Transmembrane protease serine 6
 Protein Info 
Protein ID: PT01861, Urokinase plasminogen activator surface receptor
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003997
 Compound Info 
[2,6-dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone
   Show/Hide
 C26H28N2O  1
1
LC50 > 501187.23 nM
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CP0007383
 Compound Info 
N-[1-(3,5-dimethylphenyl)-3,3-dimethyl-1-oxobutan-2-yl]-4-ethylbenzamide
   Show/Hide
 C23H29NO2  1
1
LC50 > 501187.23 nM
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CP0007786
 Compound Info 
N-[1-(3,5-dimethylbenzoyl)cyclohexyl]-2,2,2-trifluoroacetamide
   Show/Hide
 C17H20F3NO2  1
1
LC50 > 501187.23 nM
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CP0010309
 Compound Info 
(4-chlorophenyl)-[4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]methanone
   Show/Hide
 C23H21ClN2O  1
1
LC50 = 426579.52 nM
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CP0011590
 Compound Info 
4-chloro-N-[1-(4-chlorobenzoyl)-2,6-dimethyl-3,4-dihydro-2H-quinolin-4-yl]-N-(4-methylphenyl)benzamide
   Show/Hide
 C32H28Cl2N2O2  1
1
LC50 > 15135.61 nM
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CP0012428
 Compound Info 
(4-chlorophenyl)-(2-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
   Show/Hide
 C17H16ClNO  1
1
LC50 = 102329.3 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Embryo)
Cell Line Name Organism Disease
Bm5
 Cell Line Info 
Bombyx mori (Silk moth) -
NIH 3T3
 Cell Line Info 
Mus musculus (Mouse) -
BALB/3T3 clone A31
 Cell Line Info 
Mus musculus (Mouse) -
NIH-3T3-G185
 Cell Line Info 
Mus musculus (Mouse) -
HER14
 Cell Line Info 
Mus musculus (Mouse) -
B104-1-1
 Cell Line Info 
Mus musculus (Mouse) -
3T3-L1
 Cell Line Info 
Mus musculus (Mouse) -
C3H/10T1/2 clone 8
 Cell Line Info 
Mus musculus (Mouse) -
Shh Light II
 Cell Line Info 
Mus musculus (Mouse) -
MEF3.8
 Cell Line Info 
Mus musculus (Mouse) -
NIH 3T3-ras
 Cell Line Info 
Mus musculus (Mouse) -
NIH-3T3-A14
 Cell Line Info 
Mus musculus (Mouse) -
3T3/HH FlashII-7
 Cell Line Info 
Mus musculus (Mouse) -
TSC1-/- MEF
 Cell Line Info 
Mus musculus (Mouse) -
MEF-1 [Mouse fibroblast]
 Cell Line Info 
Mus musculus (Mouse) -
Ptch-deficient MEF
 Cell Line Info 
Mus musculus (Mouse) -
Rat1
 Cell Line Info 
Rattus norvegicus (Rat) -
REF52
 Cell Line Info 
Rattus norvegicus (Rat) -
SR-3Y1-1
 Cell Line Info 
Rattus norvegicus (Rat) -
SAE
 Cell Line Info 
Squalus acanthias (Spiny dogfish) -
BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper) -