All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000090 , Schneider 2

Cell Line Info

Synonyms	S2 S-2 SC-2 SL-2 SL2 Line 2 Schneider's Line S2 Schneider's line 2 Schneider Line 2 Schneider L2 Schneider's Drosophila Line2 SCHNEIDER-2 SCHNEIDER S2 Schneider S2 Drosophila Line 2 D. mel. (2) D.Mel-2 D.mel-2 WR69-DM-2 WR-DM-2 Dm2 DL2 S2-ATCC S2-Invitrogen S2-RIKEN S2U
Category	Spontaneously immortalized cell line
Organism	Drosophila melanogaster (Fruit fly)
Cellosaurus ID	CVCL_Z232

Protein ID: PT01861 , Urokinase plasminogen activator surface receptor

Protein Info

Gene Name	PLAUR
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor
Uniprot ID	Q03405

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000090

Cell Line Info

Protein ID: PT01861

Protein Info

Compound ID	Compound Name	Compound Formula
CP0262048 Compound Info	morpholin-4-yl-(2-phenyl-8-thiophen-2-ylquinolin-4-yl)methanone Show/Hide	C24H20N2O2S	3
1	IC50 = 500 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4900 nM Bioactivity Info	TI LI LO TS
3	IC50 = 8600 nM Bioactivity Info	TI LI LO TS
CP0484996 Compound Info	[2-(3-fluorophenyl)-8-thiophen-2-ylquinolin-4-yl]-morpholin-4-ylmethanone Show/Hide	C24H19FN2O2S	2
1	IC50 = 500 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7500 nM Bioactivity Info	TI LI LO TS
CP0419776 Compound Info	[2-(4-methoxyphenyl)-8-thiophen-2-ylquinolin-4-yl]-morpholin-4-ylmethanone Show/Hide	C25H22N2O3S	2
1	IC50 = 2200 nM Bioactivity Info	TI LI LO TS
2	IC50 = 12300 nM Bioactivity Info	TI LI LO TS
CP0557980 Compound Info	[2-(3-methoxyphenyl)-8-thiophen-2-ylquinolin-4-yl]-morpholin-4-ylmethanone Show/Hide	C25H22N2O3S	2
1	IC50 = 2200 nM Bioactivity Info	TI LI LO TS
2	IC50 = 12000 nM Bioactivity Info	TI LI LO TS
CP0484993 Compound Info	morpholin-4-yl-[2-phenyl-8-(1,3-thiazol-5-yl)quinolin-4-yl]methanone Show/Hide	C23H19N3O2S	2
1	IC50 = 5800 nM Bioactivity Info	TI LI LO TS
2	IC50 = 80500 nM Bioactivity Info	TI LI LO TS
CP0484673 Compound Info	morpholin-4-yl-[2-phenyl-8-(2-phenylethyl)quinolin-4-yl]methanone Show/Hide	C28H26N2O2	1
1	IC50 = 6200 nM Bioactivity Info	TI LI LO TS
CP0423444 Compound Info	morpholin-4-yl-[2-phenyl-8-(2-phenylethynyl)quinolin-4-yl]methanone Show/Hide	C28H22N2O2	2
1	IC50 = 8500 nM Bioactivity Info	TI LI LO TS
2	IC50 = 50000 nM Bioactivity Info	TI LI LO TS
CP0471163 Compound Info	morpholin-4-yl-(2-pyridin-3-yl-8-thiophen-2-ylquinolin-4-yl)methanone Show/Hide	C23H19N3O2S	2
1	IC50 = 8500 nM Bioactivity Info	TI LI LO TS
2	IC50 = 22700 nM Bioactivity Info	TI LI LO TS
CP0423438 Compound Info	morpholin-4-yl-(2-phenyl-8-thiophen-2-yl-1,6-naphthyridin-4-yl)methanone Show/Hide	C23H19N3O2S	3
1	IC50 = 9300 nM Bioactivity Info	TI LI LO TS
2	IC50 = 10400 nM Bioactivity Info	TI LI LO TS
3	Kd = 13000 nM Bioactivity Info	TI LI LO TS
CP0419811 Compound Info	2-phenyl-4-(1-piperidin-4-ylpyrazol-3-yl)-8-thiophen-2-ylquinoline Show/Hide	C27H24N4S	1
1	IC50 = 9500 nM Bioactivity Info	TI LI LO TS
CP0531561 Compound Info	(2,8-diphenylquinolin-4-yl)-morpholin-4-ylmethanone Show/Hide	C26H22N2O2	2
1	IC50 = 9800 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13900 nM Bioactivity Info	TI LI LO TS
CP0419810 Compound Info	(2-phenyl-8-thiophen-2-ylquinolin-4-yl)-piperazin-1-ylmethanone Show/Hide	C24H21N3OS	1
1	IC50 = 13100 nM Bioactivity Info	TI LI LO TS
CP0423738 Compound Info	[4-(3-chlorophenyl)piperazin-1-yl]-(2-phenyl-8-thiophen-2-ylquinolin-4-yl)methanone Show/Hide	C30H24ClN3OS	1
1	IC50 = 13400 nM Bioactivity Info	TI LI LO TS
CP0479973 Compound Info	2-[4-(morpholine-4-carbonyl)-2-phenylquinolin-8-yl]isoindole-1,3-dione Show/Hide	C28H21N3O4	2
1	IC50 = 25000 nM Bioactivity Info	TI LI LO TS
2	IC50 = 73800 nM Bioactivity Info	TI LI LO TS
CP0498450 Compound Info	(8-methyl-2-phenylquinolin-4-yl)-morpholin-4-ylmethanone Show/Hide	C21H20N2O2	2
1	IC50 = 89700 nM Bioactivity Info	TI LI LO TS
2	IC50 = 141000 nM Bioactivity Info	TI LI LO TS

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han