General Information of the Cell Line
Cell Line ID
CL000019
Cell Line Name
Rat1
Synonyms
Rat-1
RAT-1
Rat 1
Category
Spontaneously immortalized cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0492
Tissue Information
Embryo
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01007, Alpha-1B adrenergic receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0450310
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline
   Show/Hide
C30H40N4O
  1
1
Ki = 15.85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0056747
 Compound Info 
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)-1(2H)-phthalazinone
   Show/Hide
C39H49ClN4O2
  1
1
Ki = 31.62 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0294233
 Compound Info 
4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
   Show/Hide
C22H24ClN3O
  1
1
Ki = 50.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450309
 Compound Info 
8-[4-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]piperazin-1-yl]quinoline
   Show/Hide
C32H44N4O
  1
1
Ki = 50.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0469081
 Compound Info 
(E)-3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]prop-2-enoic acid
   Show/Hide
C33H42N4O3
  1
1
Ki = 79.43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117550
 Compound Info 
6,7-Dibromo-3-[(2S,5R)-5-(6-bromo-1H-indol-3-yl)-4-methyl-piperazin-2-yl]-1H-indol-4-ol
   Show/Hide
C21H19Br3N4O
  1
1
Ki = 80 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465007
 Compound Info 
8-[4-[3-[4-[3-(azepan-1-yl)propoxy]phenyl]propyl]piperazin-1-yl]quinoline
   Show/Hide
C31H42N4O
  1
1
Ki = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380720
 Compound Info 
6-Bromo-3-[4-(1H-indol-3-yl)-1H-imidazol-2-yl]-1H-indole
   Show/Hide
C19H13BrN4
  1
1
Ki = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465335
 Compound Info 
6-Bromo-3-[2-(1H-indol-3-yl)-1H-imidazol-4-yl]-1H-indole
   Show/Hide
C19H13BrN4
  1
1
Ki = 170 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450308
 Compound Info 
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]propanoic acid
   Show/Hide
C33H44N4O3
  1
1
Ki = 199.53 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0468325
 Compound Info 
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-benzylquinolin-2-yl]propanoic acid
   Show/Hide
C40H50N4O3
  1
1
Ki = 251.19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450305
 Compound Info 
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-butylquinolin-2-yl]propanoic acid
   Show/Hide
C37H52N4O3
  1
1
Ki = 398.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466612
 Compound Info 
6-bromo-3-[4-(6-bromo-1H-3-indolyl)-1H-2-imidazolyl]-1H-indole
   Show/Hide
C19H12Br2N4
  1
1
Ki = 520 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0250631
 Compound Info 
[5-(6-bromo-1H-indol-3-yl)-1H-imidazol-2-yl]-(6-hydroxy-1H-indol-3-yl)methanone
   Show/Hide
C20H13BrN4O2
  1
1
Ki = 740 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441505
 Compound Info 
(6-Hydroxy-1H-indol-3-yl)-[5-(1H-indol-3-yl)-1H-imidazol-2-yl]-methanone
   Show/Hide
C20H14N4O2
  1
1
Ki = 1150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0681610
 Compound Info 
4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
   Show/Hide
C28H32N4O5
  1
1
Ki < 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0748832
 Compound Info 
(R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
   Show/Hide
C26H31F2N3O5
  1
1
Ki < 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0860700
 Compound Info 
(R)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
   Show/Hide
C27H32N4O5
  1
1
Ki < 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0915880
 Compound Info 
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
   Show/Hide
C27H31F2N3O5
  1
1
Ki < 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0890877
 Compound Info 
(R)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
   Show/Hide
C26H32FN3O5
  1
1
Ki < 1584.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0896098
 Compound Info 
4-(4-methylbenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
   Show/Hide
C26H34ClN3O3
  1
1
Ki < 1584.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0915882
 Compound Info 
(R)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
   Show/Hide
C26H31F2N3O5
  1
1
Ki < 1584.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0873040
 Compound Info 
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-methylbenzoyl)piperazin-2-one hydrochloride
   Show/Hide
C27H34ClN3O3
  1
1
Ki < 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450306
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-2-carboxylic acid
   Show/Hide
C31H40N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0450307
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-3-carboxylic acid
   Show/Hide
C31H40N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0461430
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-4-carboxylic acid
   Show/Hide
C31H40N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0461431
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-6-carboxylic acid
   Show/Hide
C31H40N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0464411
 Compound Info 
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-ethylquinolin-2-yl]propanoic acid
   Show/Hide
C35H48N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465009
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-7-carboxylic acid
   Show/Hide
C31H40N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0468326
 Compound Info 
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-5-carbonitrile
   Show/Hide
C31H39N5O
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0512424
 Compound Info 
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-3-yl]propanoic acid
   Show/Hide
C33H44N4O3
  1
1
Ki > 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0681609
 Compound Info 
4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
   Show/Hide
C26H32FN3O5
  1
1
Ki < 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0860704
 Compound Info 
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-pivaloylpiperazin-2-one hydrochloride
   Show/Hide
C23H36ClN3O3
  1
1
Ki < 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0890876
 Compound Info 
4-(4-chlorobenzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
   Show/Hide
C26H31Cl2N3O3
  1
1
Ki < 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0890879
 Compound Info 
4-benzoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
   Show/Hide
C25H32ClN3O3
  1
1
Ki < 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0918636
 Compound Info 
4-benzoyl-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
   Show/Hide
C26H32ClN3O3
  1
1
Ki < 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0854415
 Compound Info 
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one hydrochloride
   Show/Hide
C26H31ClFN3O3
  1
1
Ki < 3162.28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01089, Alpha-1A adrenergic receptor
 Protein Info 
Protein ID: PT01849, Alpha-1B adrenergic receptor
 Protein Info 
Protein ID: PT01045, Phosphoinositide 3-kinase alpha
 Protein Info 
Protein ID: PT07498, Phosphoinositide-3-kinase catalytic alpha polypeptide
 Protein Info 
Protein ID: PT00999, PIK3CD
 Protein Info 
Protein ID: PT01033, Serine/threonine protein kinase PIK3CB
 Protein Info 
Protein ID: PT06232, Serine/threonine protein kinase PIK3CB
 Protein Info 
Protein ID: PT01029, Serine/threonine protein kinase PIK3CG
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Embryo)
Cell Line Name Organism Disease
Bm5
 Cell Line Info 
Bombyx mori (Silk moth) -
Schneider 2
 Cell Line Info 
Drosophila melanogaster (Fruit fly) -
NIH 3T3
 Cell Line Info 
Mus musculus (Mouse) -
BALB/3T3 clone A31
 Cell Line Info 
Mus musculus (Mouse) -
NIH-3T3-G185
 Cell Line Info 
Mus musculus (Mouse) -
HER14
 Cell Line Info 
Mus musculus (Mouse) -
B104-1-1
 Cell Line Info 
Mus musculus (Mouse) -
3T3-L1
 Cell Line Info 
Mus musculus (Mouse) -
C3H/10T1/2 clone 8
 Cell Line Info 
Mus musculus (Mouse) -
Shh Light II
 Cell Line Info 
Mus musculus (Mouse) -
MEF3.8
 Cell Line Info 
Mus musculus (Mouse) -
NIH 3T3-ras
 Cell Line Info 
Mus musculus (Mouse) -
NIH-3T3-A14
 Cell Line Info 
Mus musculus (Mouse) -
3T3/HH FlashII-7
 Cell Line Info 
Mus musculus (Mouse) -
TSC1-/- MEF
 Cell Line Info 
Mus musculus (Mouse) -
MEF-1 [Mouse fibroblast]
 Cell Line Info 
Mus musculus (Mouse) -
Ptch-deficient MEF
 Cell Line Info 
Mus musculus (Mouse) -
REF52
 Cell Line Info 
Rattus norvegicus (Rat) -
SR-3Y1-1
 Cell Line Info 
Rattus norvegicus (Rat) -
SAE
 Cell Line Info 
Squalus acanthias (Spiny dogfish) -
BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper) -