Brief Information of the Cell Line and Protein
Cell Line ID: CL000019 , Rat1
Synonyms
Rat-1
RAT-1
Rat 1
Category Spontaneously immortalized cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0492
Protein ID: PT01849 , Alpha-1B adrenergic receptor
Gene Name ADRA1B
Organism Mesocricetus auratus, Golden hamster
Protein Classification Membrane receptor
Uniprot ID P18841
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000019  Protein ID: PT01849
 
Compound ID Compound Name Compound Formula
CP0046703
1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
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C24H26ClFN4O
 1
1
Ki = 0.33 nM
   TI
   LI
   LO
   TS
CP0228798
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
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C26H29FN8O
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0126862
1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine
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C24H23FN4
 1
1
Ki = 1.9 nM
   TI
   LI
   LO
   TS
CP0126860
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
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C27H30FN7O
 1
1
Ki = 6 nM
   TI
   LI
   LO
   TS
CP0156782
1-(4-fluorophenyl)-3-(1-methylpiperidin-4-yl)-5-(1-methyl-1,2,4-triazol-3-yl)indole
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C23H24FN5
 1
1
Ki = 6.4 nM
   TI
   LI
   LO
   TS