| Compound ID |
Compound Name |
Compound Formula |
|
CP0124222
|
(2S,3R)-3-methyl-1-N-[8-(1,1,1-trifluoro-2-methylpropan-2-yl)-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl]pyrrolidine-1,2-dicarboxamide
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|
C20H23F3N6O2S
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0144577
|
(2S,3R)-1-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)-3-methylpyrrolidine-1,2-dicarboxamide
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|
C20H26N6O2S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0055472
|
(2S)-1-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)pyrrolidine-1,2-dicarboxamide
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|
C19H24N6O2S
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0176371
|
(2S)-1-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)-2-methylpyrrolidine-1,2-dicarboxamide
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|
C20H26N6O2S
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0120405
|
(2S,3R)-3-methyl-1-N-[7-(1,1,1-trifluoro-2-methylpropan-2-yl)-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl]pyrrolidine-1,2-dicarboxamide
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|
C19H22F3N5O2S2
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0099117
|
(2R)-1-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)-2-[(dimethylamino)methyl]pyrrolidine-1,2-dicarboxamide
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|
C22H31N7O2S
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0099116
|
(1S,5R)-2-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)-2-azabicyclo[3.1.0]hexane-1,2-dicarboxamide
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|
C20H24N6O2S
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
|
CP0099118
|
(2S,3S)-1-N-(7-tert-butyl-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-3-methylpyrrolidine-1,2-dicarboxamide
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|
C19H25N5O2S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0215337
|
(2S,3S)-1-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)-3-[(dimethylamino)methyl]pyrrolidine-1,2-dicarboxamide
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|
C22H31N7O2S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0055470
|
(2S)-1-N-(7-tert-butyl-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)pyrrolidine-1,2-dicarboxamide
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|
C18H23N5O2S2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0095462
|
(2S,3R)-1-N-(7-tert-butyl-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-3-methylpyrrolidine-1,2-dicarboxamide
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|
C19H25N5O2S2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0109038
|
(2S)-1-N-[5-(2-tert-butylpyrimidin-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
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|
C18H24N6O2S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0124221
|
(2S)-1-N-[7-(cyclopropylmethyl)-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl]pyrrolidine-1,2-dicarboxamide
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|
C18H21N5O2S2
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0055471
|
(2S,3S)-1-N-(7-tert-butyl-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-3-[(dimethylamino)methyl]pyrrolidine-1,2-dicarboxamide
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|
C21H30N6O2S2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0059183
|
(2S)-1-N-(7-tert-butyl-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-2-methylpyrrolidine-1,2-dicarboxamide
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|
C19H25N5O2S2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0055473
|
(2S,4R)-1-N-(8-tert-butyl-4,5-dihydro-[1,3]thiazolo[4,5-h]quinazolin-2-yl)-4-(dimethylamino)pyrrolidine-1,2-dicarboxamide
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|
C21H29N7O2S
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0054682
|
(2S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
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|
C17H23N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0176375
|
(1S,5R)-2-N-(7-tert-butyl-4,5-dihydro-[1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)-2-azabicyclo[3.1.0]hexane-1,2-dicarboxamide
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|
C19H23N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
