General Information of the Protein
Protein ID
PT05333
Protein Name
Meprin A subunit alpha
Secondarily
Protein Name
Endopeptidase-2
N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha
PABA peptide hydrolase
PPH alpha
Gene Name
MEP1A
Sequence
MAWIRSTCILFFTLLFAHIAAVPIKYLPEENVHDADFGEQKDISEINLAAGLDLFQGDILLQKSRNGLRDPNTRWTFPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTTHTLLDHCTFEKANICGMIQGTRDDTDWAHQDSAQAGEVDHTLLGQCTGAGYFMQFSTSSGSAEEAALLESRILYPKRKQQCLQFFYKMTGSPSDRLVVWVRRDDSTGNVRKLVKVQTFQGDDDHNWKIAHVVLKEEQKFRYLFQGTKGDPQNSTGGIYLDDITLTETPCPTGVWTVRNFSQVLENTSKGDKLQSPRFYNSEGYGFGVTLYPNSRESSGYLRLAFHVCSGENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVENTGPLEDHNWPQYFRDPCDPNPCQNDGICVNVKGMASCRCISGHAFFYTGERCQAVQVHGSVLGMVIGGTAGVIFLTFSIIAILSQRPRK
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Organism
Homo sapiens, Human
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Primary ID:
Q16819

Secondarily ID:
A2RRM4
B0AZP9
B2RCS2
Q8TDC9
Q9H1R1
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Ensembl ID
ENSG00000112818
HGNC ID
HGNC:7015
Subcellular Location
Membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000090 , Schneider 2
Compound ID Compound Name Compound Formula
CP0072521
3-[[[2-(hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]methyl]benzoic acid
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C17H18N2O7S
 1
1
IC50 = 3290 nM
   TI
   LI
   LO
   TS
CP0457080
3-[[(3-carboxyphenyl)sulfonyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acid
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C17H16N2O8S
 1
1
IC50 = 27350 nM
   TI
   LI
   LO
   TS