Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10336717, Compound 217
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Canonical SMILES
CO[C@H]1CC[C@@]2(Cc3ccc(Br)cc3C22N=C(N)N(C)C2=O)CC1
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Compound Formula C18H22BrN3O2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000090 Schneider 2
 Cell Line Info 
Drosophila melanogaster (Fruit fly)  1
1
IC50 = 32.3 nM
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