| Compound ID |
Compound Name |
Compound Formula |
|
CP0424067
|
8-[2-[(3S,4S)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H20F4N4O
|
1
|
| 1 |
IC50 < 20 nM
|
|
|
|
CP0487496
|
4-[[3-methyl-5-(1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-2-yl]oxymethyl]bicyclo[2.2.2]octan-1-amine
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|
C21H25N5O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0516638
|
8-[2-[(3R,4R)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H20F4N4O
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0424062
|
1,6-dimethyl-5-(7-methyl-2-pyridin-3-ylindazol-5-yl)pyridin-2-one
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|
C20H18N4O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0424053
|
1-methyl-5-[8-methyl-2-(4-propan-2-ylpiperazin-1-yl)quinazolin-6-yl]pyridin-2-one
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|
C22H27N5O
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0516639
|
8-[2-[(3S,4R)-3-fluoropiperidin-4-yl]-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H20F4N4O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0526845
|
6-fluoro-1-methyl-5-[2-piperidin-4-yl-7-(trifluoromethyl)indazol-5-yl]pyridin-2-one
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|
C19H18F4N4O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0531896
|
8-[2-piperidin-4-yl-7-(trifluoromethyl)indazol-5-yl]-2,3-dihydro-1H-indolizin-5-one
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|
C21H21F3N4O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0526851
|
5-methyl-7-(7-methyl-2-piperidin-4-ylindazol-5-yl)furo[3,2-c]pyridin-4-one
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|
C21H22N4O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0409319
|
8-(7-methyl-2-piperidin-4-ylindazol-5-yl)-2,3-dihydro-1H-indolizin-5-one
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|
C21H24N4O
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0409318
|
6-fluoro-1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C19H21FN4O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0562397
|
5-(7-cyclopropyl-2-piperidin-4-ylindazol-5-yl)-1,6-dimethylpyridin-2-one
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|
C22H26N4O
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0424060
|
5-[2-(5,5-difluoropiperidin-3-yl)-7-methylindazol-5-yl]-1,6-dimethylpyridin-2-one
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|
C20H22F2N4O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0526844
|
5-[2-(4,4-difluoropiperidin-3-yl)-7-methylindazol-5-yl]-1,6-dimethylpyridin-2-one
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|
C20H22F2N4O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0525563
|
1,6-dimethyl-5-[7-methyl-2-[1-(2,2,2-trifluoroethyl)piperidin-3-yl]indazol-5-yl]pyridin-2-one
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|
C22H25F3N4O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0424056
|
1,3-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0526841
|
1,6-dimethyl-5-[2-piperidin-4-yl-7-(trifluoromethyl)indazol-5-yl]pyridin-2-one
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|
C20H21F3N4O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0553984
|
5-[2-[1-[2-(dimethylamino)acetyl]piperidin-4-yl]-7-methylindazol-5-yl]-1,6-dimethylpyridin-2-one
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|
C24H31N5O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0424057
|
6-chloro-1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C19H21ClN4O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0531875
|
5-[2-(4-cyclobutylpiperazin-1-yl)quinazolin-6-yl]-1-methylpyridin-2-one
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|
C22H25N5O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0526843
|
1,6-dimethyl-5-(7-methyl-2-piperidin-3-ylindazol-5-yl)pyridin-2-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0526842
|
1,6-dimethyl-5-[7-methyl-2-(1-methylpiperidin-4-yl)indazol-5-yl]pyridin-2-one
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|
C21H26N4O
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0525568
|
1,6-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0557738
|
5-(7-chloro-2-piperidin-4-ylindazol-5-yl)-1,6-dimethylpyridin-2-one
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|
C19H21ClN4O
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0409312
|
1-methyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C19H22N4O
|
1
|
| 1 |
IC50 = 7600 nM
|
|
|
|
CP0409314
|
1,4-dimethyl-5-(7-methyl-2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C20H24N4O
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0531894
|
1-methyl-5-(2-piperidin-4-ylindazol-5-yl)pyridin-2-one
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|
C18H20N4O
|
1
|
| 1 |
IC50 = 49000 nM
|
|
|
|
CP0568892
|
(2E)-2-[(2E,4E)-5-[3,3-dimethyl-1-[6-[[4-[[3-methyl-5-(1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-2-yl]oxymethyl]-1-bicyclo[2.2.2]octanyl]amino]-6-oxohexyl]-5-sulfoindol-1-ium-2-yl]penta-2,4-dienylidene]-1-ethyl-3,3-dimethylindole-5-sulfonic acid;2,2,2-trifluoroacetate
Show/Hide
|
C56H64F3N7O10S2
|
1
|
| 1 |
Kd = 65 nM
|
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|
