Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10336717, Compound 470
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 PubChem ID
CID: 58197508
Canonical SMILES
CN1OC2(N=C1N)c1cc(ccc1CC21CCc2c(C1)c(C)nn2C)-c1cc(F)cc(Cl)c1
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Compound Formula C25H25ClFN5O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000090 Schneider 2
 Cell Line Info 
Drosophila melanogaster (Fruit fly)  1
1
IC50 = 67 nM
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