Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9212153, 264,Ex. 217
    Show/Hide
 PubChem ID
CID: 58197853
Canonical SMILES
COC1CCC2(Cc3ccc(cc3C22N=C(N)NC2=O)C#CC2CC2)CC1
    Show/Hide
Compound Formula C22H25N3O2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000090 Schneider 2
 Cell Line Info 
Drosophila melanogaster (Fruit fly)  1
1
IC50 = 29.2 nM
   TI
   LI
   LO
   TS