Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(4-chlorophenyl)methyl]-2-[(3R,8E,11S)-3-(4-fluorophenyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]acetamide
    Show/Hide
 PubChem ID
CID: 71460284
SID: 163440987
Canonical SMILES
Fc1ccc(cc1)[C@@H]1COC(=O)[C@H](CC(=O)NCc2ccc(Cl)cc2)C\C=C\CCC(=O)N1
    Show/Hide
Compound Formula C25H26ClFN2O4
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000387 C3H/10T1/2 clone 8
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS