Brief Information of the Compound and Protein
Compound Name
N-[2,4-dimethyl-5-(5-methyl-1H-pyrazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide
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PubChem ID
CID: 156021408
Canonical SMILES
Cc1n[nH]cc1-c1cc(NC(=O)c2ccc(OCc3ccccn3)cc2)c(C)cc1C
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Compound Formula C25H24N4O2
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000387 C3H/10T1/2 clone 8 Mus musculus (Mouse)  1
1
EC50 = 1.1 nM
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