| Compound ID |
Compound Name |
Compound Formula |
|
CP0243589
|
4-[2-methyl-4-(2-oxo-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]-N-(1-methylpiperidin-4-yl)benzamide
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|
C41H35N5O2
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0023857
|
N-(1-methylpiperidin-4-yl)-4-[4-(2-oxo-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-1-yl)-2-(trifluoromethyl)phenyl]benzamide
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|
C41H32F3N5O2
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0503237
|
4-[4-[9-(2-aminopyrimidin-5-yl)-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-(trifluoromethyl)phenyl]-N-(1-methylpiperidin-4-yl)benzamide
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|
C36H30F3N7O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0512569
|
N-(1-methylpiperidin-4-yl)-4-[4-[2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1-yl]-2-(trifluoromethyl)phenyl]benzamide
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|
C35H29F3N6O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0503175
|
N-methyl-4-[4-(2-oxo-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-1-yl)-2-(trifluoromethyl)phenyl]benzamide
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|
C36H23F3N4O2
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0436112
|
4-[4-(2-oxo-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-1-yl)-2-(trifluoromethyl)phenyl]benzoic acid
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|
C35H20F3N3O3
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0452004
|
1-[4-[4-(oxan-2-yloxymethyl)phenyl]-3-(trifluoromethyl)phenyl]-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-2-one
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|
C40H30F3N3O3
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0465089
|
4-[4-(2-oxo-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-1-yl)-2-(trifluoromethyl)phenyl]benzamide
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|
C35H21F3N4O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0483779
|
4-[2-methyl-4-[2-oxo-9-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzo[h][1,6]naphthyridin-1-yl]phenyl]-N-(1-methylpiperidin-4-yl)benzamide
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|
C39H34N6O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0465088
|
1-[4-[4-(hydroxymethyl)phenyl]-3-(trifluoromethyl)phenyl]-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-2-one
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|
C35H22F3N3O2
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0499736
|
4-[4-[9-(6-aminopyridin-3-yl)-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]-N-(1-methylpiperidin-4-yl)benzamide
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|
C37H34N6O2
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0441402
|
4-[2-methyl-4-[9-(1-methylpyrazol-4-yl)-2-oxobenzo[h][1,6]naphthyridin-1-yl]phenyl]-N-(1-methylpiperidin-4-yl)benzamide
Show/Hide
|
C36H34N6O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0499167
|
4-[2-methyl-4-[2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1-yl]phenyl]-N-(1-methylpiperidin-4-yl)benzamide
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|
C35H32N6O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0521650
|
methyl 4-[4-(2-oxo-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-1-yl)-2-(trifluoromethyl)phenyl]benzoate
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|
C36H22F3N3O3
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0501237
|
4-[2-methyl-4-(2-oxobenzo[h][1,6]naphthyridin-1-yl)phenyl]-N-(1-methylpiperidin-4-yl)benzamide
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|
C32H30N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0543985
|
4-[7-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]-1,4-oxazepane
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|
C18H23N7O2S
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0354280
|
(3R)-3-methyl-4-[5-propan-2-yl-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C16H20N6OS
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0347328
|
(3R)-3-methyl-4-[5-morpholin-4-yl-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C17H21N7O2S
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
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CP0198509
|
(3R)-3-methyl-4-[5-[(3S)-3-methylmorpholin-4-yl]-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C18H23N7O2S
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
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CP0567500
|
(3R)-3-methyl-4-[5-(oxan-4-yl)-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C18H22N6O2S
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
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CP0355964
|
(3R)-3-methyl-4-[5-[(3S)-3-methylmorpholin-4-yl]-2-(2H-triazol-4-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C17H22N8O2S
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
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CP0534120
|
(3R)-4-[2-(1H-imidazol-5-yl)-5-[(3S)-3-methylmorpholin-4-yl]-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]-3-methylmorpholine
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|
C18H23N7O2S
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0228417
|
(3R)-3-methyl-4-[5-[(3S)-3-methylmorpholin-4-yl]-2-(1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C18H23N7O2S
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
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CP0529546
|
(3R)-3-methyl-4-[5-(morpholin-4-ylmethyl)-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C18H23N7O2S
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
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CP0354279
|
(3R)-3-methyl-4-[5-(4-methylpiperazin-1-yl)-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
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|
C18H24N8OS
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
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CP0355965
|
3-[7-[(3R)-3-methylmorpholin-4-yl]-5-[(3S)-3-methylmorpholin-4-yl]-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]phenol
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|
C21H25N5O3S
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
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CP0355945
|
(3R)-4-[2-(1H-indol-4-yl)-5-[(3S)-3-methylmorpholin-4-yl]-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]-3-methylmorpholine
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|
C23H26N6O2S
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
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CP0198510
|
(3R)-3-methyl-4-[2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
Show/Hide
|
C13H14N6OS
|
1
|
| 1 |
IC50 = 603 nM
|
|
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