Brief Information of the Compound and Protein
Compound Name
(3R)-3-methyl-4-[5-(4-methylpiperazin-1-yl)-2-(1H-pyrazol-5-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]morpholine
    Show/Hide
PubChem ID
CID: 155543833
Canonical SMILES
C[C@@H]1COCCN1c1nc(nc2sc(nc12)-c1cc[nH]n1)N1CCN(C)CC1
    Show/Hide
Compound Formula C18H24N8OS
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
Q9JLN9
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001056 MEF-1 [Mouse fibroblast] Mus musculus (Mouse)  1
1
IC50 = 134 nM
   TI
   LI
   LO
   TS