General Information of the Cell Line
Cell Line ID
CL000041
Cell Line Name
LTK-
Category
Transformed cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_3392
Tissue Information
Connective tissue
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02075, Alpha-1D adrenergic receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0035002
 Compound Info 
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
   Show/Hide
C20H28N2O5S
  1
1
Ki = 0.07 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0300622
 Compound Info 
7-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C24H27N3O4
  1
1
Ki = 0.21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0277233
 Compound Info 
6-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C22H25N3O4S
  1
1
Ki = 0.24 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0150194
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-7-carboxylic acid amide
   Show/Hide
C26H26N4O4S
  1
1
Ki = 0.27 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0285996
 Compound Info 
2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,6-triaza-fluorene-1,3-dione
   Show/Hide
C24H24N4O3S
  1
1
Ki = 0.28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0257880
 Compound Info 
8-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C25H24ClN3O3S
  1
1
Ki = 0.31 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0215556
 Compound Info 
5-[2-[(3aR,9bR)-6-methoxy-1,3,3a,4,5,9b-hexahydrobenzo[e]isoindol-2-yl]ethyl]-8-thia-3,5,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),10,12-tetraene-4,6-dione
   Show/Hide
C24H24N4O3S
  1
1
Ki = 0.37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0107697
 Compound Info 
N-[3-[2-[(3aR,9bR)-6-methoxy-1,3,3a,4,5,9b-hexahydrobenzo[e]isoindol-2-yl]ethyl]-2,4-dioxo-1H-quinazolin-7-yl]acetamide
   Show/Hide
C25H28N4O4
  1
1
Ki = 0.41 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0087515
 Compound Info 
2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
   Show/Hide
C24H24N4O3S
  1
1
Ki = 0.51 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0306128
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-8-carboxylic acid amide
   Show/Hide
C26H26N4O4S
  1
1
Ki = 0.51 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0111306
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-thieno[3,4-d]pyrimidine-2,4-dione
   Show/Hide
C21H23N3O3S
  1
1
Ki = 0.52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117377
 Compound Info 
7-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C23H24ClN3O3
  1
1
Ki = 0.58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0306296
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-8-carbonitrile
   Show/Hide
C26H24N4O3S
  1
1
Ki = 0.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0272523
 Compound Info 
6-Chloro-2-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
   Show/Hide
C24H23ClN4O3S
  1
1
Ki = 0.61 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0111505
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C23H25N3O3
  1
1
Ki = 0.62 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0181767
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-8-carboxylic acid dimethylamide
   Show/Hide
C28H30N4O4S
  1
1
Ki = 0.63 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0105963
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C27H27N3O3S
  1
1
Ki = 0.66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0306109
 Compound Info 
(Cis)3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]furo[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C25H25N3O4
  1
1
Ki = 0.68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0303772
 Compound Info 
7,8-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C25H29N3O5
  1
1
Ki = 0.68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0278691
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-5H-9-thia-1,5,7-triaza-fluorene-6,8-dione
   Show/Hide
C24H24N4O3S
  1
1
Ki = 0.69 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0366100
 Compound Info 
5-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C23H24ClN3O3
  1
1
Ki = 0.69 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0339131
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-7-methyl-1H-thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C22H25N3O3S
  1
1
Ki = 0.71 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0272442
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-6,7-dimethyl-1H-quinazoline-2,4-dione
   Show/Hide
C25H29N3O3
  1
1
Ki = 0.73 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0111500
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-7-carbonitrile
   Show/Hide
C26H24N4O3S
  1
1
Ki = 0.74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0172953
 Compound Info 
(Cis)2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione
   Show/Hide
C25H26N4O3
  1
1
Ki = 0.74 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0311747
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-quinazoline-7-carbonitrile
   Show/Hide
C24H24N4O3
  1
1
Ki = 0.77 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0339119
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-quinazoline-7-carboxylic acid methyl ester
   Show/Hide
C25H27N3O5
  1
1
Ki = 0.77 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0172104
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-9-methyl-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C26H27N3O3S
  1
1
Ki = 0.88 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0334603
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-7,8-dimethyl-1H-quinazoline-2,4-dione
   Show/Hide
C25H29N3O3
  1
1
Ki = 0.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0277241
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C21H23N3O3S
  1
1
Ki = 0.92 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0816886
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C21H23N3O3S
  1
1
Ki = 0.92 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0049024
 Compound Info 
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
   Show/Hide
C19H25N5O4
  1
1
Ki = 1.01 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0339125
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-thieno[2,3-d]pyrimidine-2,4-dione
   Show/Hide
C21H23N3O3S
  1
1
Ki = 1.01 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0208716
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-8-methyl-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C26H27N3O3S
  1
1
Ki = 1.04 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0215114
 Compound Info 
9-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C26H27N3O4S
  1
1
Ki = 1.07 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0200691
 Compound Info 
3-Methoxy-7-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
   Show/Hide
C24H25N5O4S
  1
1
Ki = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0290436
 Compound Info 
6-Methoxy-2-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
   Show/Hide
C25H26N4O4S
  1
1
Ki = 1.1 nM
 Bioactivity Info 
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   LI
   LO
   TS
CP0104354
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-5-methyl-1H-quinazoline-2,4-dione
   Show/Hide
C24H27N3O3
  1
1
Ki = 1.13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0281096
 Compound Info 
6-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C24H27N3O4
  1
1
Ki = 1.13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0318718
 Compound Info 
8-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C24H27N3O4
  1
1
Ki = 1.15 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0308881
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-7-nitro-1H-quinazoline-2,4-dione
   Show/Hide
C23H24N4O5
  1
1
Ki = 1.2 nM
 Bioactivity Info 
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CP0107696
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-8-nitro-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C25H24N4O5S
  1
1
Ki = 1.31 nM
 Bioactivity Info 
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   LI
   LO
   TS
CP0200627
 Compound Info 
9-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C25H24ClN3O3S
  1
1
Ki = 1.32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0306131
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-thieno[3,2-d]pyrimidine-6-carboxylic acid methyl ester
   Show/Hide
C23H25N3O5S
  1
1
Ki = 1.38 nM
 Bioactivity Info 
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   LI
   LO
   TS
CP0146707
 Compound Info 
6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
   Show/Hide
C25H29N3O5
  1
1
Ki = 1.4 nM
 Bioactivity Info 
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CP0244629
 Compound Info 
8-Methoxy-2-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
   Show/Hide
C25H26N4O4S
  1
1
Ki = 1.41 nM
 Bioactivity Info 
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   LO
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CP0339071
 Compound Info 
6-Methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-7-methyl-1H-thieno[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C23H27N3O4S
  1
1
Ki = 1.45 nM
 Bioactivity Info 
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   LO
   TS
CP0293490
 Compound Info 
7-Isopropyl-6-methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-thieno[3,2-d]pyrimidine-2,4-dione
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C25H31N3O4S
  1
1
Ki = 1.5 nM
 Bioactivity Info 
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CP0316626
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1,7-dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione
   Show/Hide
C21H24N4O3
  1
1
Ki = 1.67 nM
 Bioactivity Info 
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CP0334602
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-pyrido[3,4-d]pyrimidine-2,4-dione
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C22H24N4O3
  1
1
Ki = 1.78 nM
 Bioactivity Info 
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   LO
   TS
CP0251350
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-pyrido[2,3-d]pyrimidine-2,4-dione
   Show/Hide
C22H24N4O3
  1
1
Ki = 1.99 nM
 Bioactivity Info 
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   LO
   TS
CP0193838
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
   Show/Hide
C23H23N5O3S
  1
1
Ki = 2.06 nM
 Bioactivity Info 
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   LO
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CP0334912
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-5H-9-thia-1,3,5,7-tetraaza-fluorene-6,8-dione
   Show/Hide
C23H23N5O3S
  1
1
Ki = 2.08 nM
 Bioactivity Info 
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   LO
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CP0363623
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-6-carbonitrile
   Show/Hide
C26H24N4O3S
  1
1
Ki = 2.08 nM
 Bioactivity Info 
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CP0251349
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2-methyl-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
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C24H25N5O3S
  1
1
Ki = 2.31 nM
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CP0220027
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-pyrido[3,2-d]pyrimidine-2,4-dione
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C22H24N4O3
  1
1
Ki = 2.5 nM
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CP0300093
 Compound Info 
6-Chloro-7-methoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-quinazoline-2,4-dione
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C24H26ClN3O4
  1
1
Ki = 2.71 nM
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CP0101288
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-8-carboxylic acid methyl ester
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C27H27N3O5S
  1
1
Ki = 2.84 nM
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CP0099011
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-6,8-dimethyl-1H-quinazoline-2,4-dione
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C25H29N3O3
  1
1
Ki = 2.86 nM
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CP0281405
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-pyrido[4,3-d]pyrimidine-2,4-dione
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C22H24N4O3
  1
1
Ki = 2.87 nM
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CP0278639
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,3-dimethyl-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
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C25H27N5O3S
  1
1
Ki = 3.28 nM
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CP0094875
 Compound Info 
6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1-methyl-1H-quinazoline-2,4-dione
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C26H31N3O5
  1
1
Ki = 3.71 nM
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CP0507035
 Compound Info 
2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5,7-tetraaza-fluorene-1,3-dione
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C23H23N5O3S
  1
1
Ki = 3.74 nM
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CP0200084
 Compound Info 
3-Chloro-7-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
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C23H22ClN5O3S
  1
1
Ki = 3.83 nM
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CP0405674
 Compound Info 
8-Chloro-2-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
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C24H23ClN4O3S
  1
1
Ki = 4.16 nM
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CP0193331
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dione
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C27H27N3O3S
  1
1
Ki = 4.4 nM
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CP0117265
 Compound Info 
(Cis)3-[4-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-butyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C27H29N3O3S
  1
1
Ki = 4.77 nM
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CP0278803
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-pteridine-2,4-dione
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C21H23N5O3
  1
1
Ki = 5.49 nM
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CP0296008
 Compound Info 
(Cis)3-[2-(8-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C25H25N3O3S
  1
1
Ki = 5.76 nM
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CP0081691
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,4-dioxo-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-d]pyrimidine-9-carbonitrile
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C26H24N4O3S
  1
1
Ki = 6.6 nM
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CP0352054
 Compound Info 
3-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-7-trifluoromethyl-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C26H24F3N3O3S
  1
1
Ki = 6.84 nM
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CP0257865
 Compound Info 
(Cis)3-[3-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-propyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C26H27N3O3S
  1
1
Ki = 7.7 nM
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CP0272620
 Compound Info 
6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-3H-quinazolin-4-one
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C25H29N3O4
  1
1
Ki = 7.79 nM
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CP0331914
 Compound Info 
(Cis)3-[2-(9-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C25H25N3O3S
  1
1
Ki = 8.67 nM
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CP0299620
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-3-phenyl-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
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C29H27N5O3S
  1
1
Ki = 19.8 nM
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CP0214818
 Compound Info 
6-Chloro-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C25H24ClN3O3S
  1
1
Ki = 25 nM
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CP0104415
 Compound Info 
2-Amino-4,5-dimethoxy-N-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-benzamide
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C24H31N3O4
  1
1
Ki = 32.65 nM
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CP0300109
 Compound Info 
(Cis)3-[2-(7-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
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C25H25N3O3S
  1
1
Ki = 47 nM
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CP0339046
 Compound Info 
6,7-Dimethoxy-2-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-3,4-dihydro-2H-isoquinolin-1-one
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C26H32N2O4
  1
1
Ki = 58.4 nM
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CP0350146
 Compound Info 
6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,3-dihydro-1H-quinazolin-4-one
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C25H31N3O4
  1
1
Ki = 71.97 nM
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CP0311748
 Compound Info 
2-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]isoindole
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C26H34N2O3
  1
1
Ki = 83.4 nM
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CP0307684
 Compound Info 
7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2-phenyl-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione
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C29H27N5O3S
  1
1
Ki = 160 nM
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CP0103803
 Compound Info 
6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-3,4-dihydro-1H-quinazolin-2-one
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C25H31N3O4
  1
1
Ki = 168.2 nM
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CP0280474
 Compound Info 
2-[2-(6,7-Dimethoxy-1,4-dihydro-2H-quinazolin-3-yl)-ethyl]-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]isoindole
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C25H33N3O3
  1
1
Ki = 189 nM
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Protein ID: PT01849, Alpha-1B adrenergic receptor
 Protein Info 
Protein ID: PT01650, Alpha-2A adrenergic receptor
 Protein Info 
Protein ID: PT01598, Alpha-2C adrenergic receptor
 Protein Info 
Protein ID: PT01588, Corticotropin-releasing factor receptor 1
 Protein Info 
Protein ID: PT01195, D(1A) dopamine receptor
 Protein Info 
Protein ID: PT01169, D(1B) dopamine receptor
 Protein Info 
Protein ID: PT01005, D(2) dopamine receptor
 Protein Info 
Protein ID: PT01161, D(4) dopamine receptor
 Protein Info 
Protein ID: PT01372, Endothelin-1 receptor
 Protein Info 
Protein ID: PT04248, Glutamate receptor ionotropic, NMDA 2A
 Protein Info 
Protein ID: PT02751, Glutamate receptor ionotropic, NMDA 2B
 Protein Info 
Protein ID: PT01155, Growth hormone secretagogue receptor type 1
 Protein Info 
Protein ID: PT06097, Inward rectifier K(+) channel Kir6.2
 Protein Info 
Protein ID: PT00854, Metabotropic glutamate receptor 5
 Protein Info 
Protein ID: PT02768, Voltage-gated potassium channel HK2
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Connective tissue)
Cell Line Name Organism Disease
human L929
 Cell Line Info 
Homo sapiens (Human) -
L-M(TK-)
 Cell Line Info 
Mus musculus (Mouse) -
NCTC clone 929
 Cell Line Info 
Mus musculus (Mouse) -
A-9
 Cell Line Info 
Mus musculus (Mouse) -
L Wnt-3A
 Cell Line Info 
Mus musculus (Mouse) -
LAP1
 Cell Line Info 
Mus musculus (Mouse) -
LV2
 Cell Line Info 
Mus musculus (Mouse) -