General Information of the Cell Line
Cell Line ID
CL000309
Cell Line Name
NCTC clone 929
Synonyms
NCTC 929
NCTC-929
NCTC929
NCTC-929L
L cell
L cells
L-cell
L-cells
L cell line
L
Strain L-929
L-929
L 929
L929
L929(NCTC)
Clone 929
Earles's cells
Earle's L cells
Category
Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0462
Tissue Information
Connective tissue
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
 Protein Info 
Compound ID Compound Name Compound Formula
CP0134845
 Compound Info 
1-(17-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21FN2O
  1
1
IC50 = 1.148 nM
 Bioactivity Info 
   TI
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CP0400980
 Compound Info 
1-(17-chloro-3,13-dioxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C18H19ClN2O2
  1
1
IC50 = 1.905 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0123725
 Compound Info 
N,N-dimethyl-1-(17-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)methanamine
   Show/Hide
C20H24N2O
  1
1
IC50 = 3.09 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0105756
 Compound Info 
1-(17-chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21ClN2O
  1
1
IC50 = 3.467 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0438133
 Compound Info 
N,N-dimethyl-3-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)propan-1-amine
   Show/Hide
C21H26N2O
  1
1
IC50 = 3.89 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0393174
 Compound Info 
1-(16-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21FN2O
  1
1
IC50 = 6.918 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0026495
 Compound Info 
CHEBI:51137
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C18H20N2
  1
1
IC50 = 10.47 nM
 Bioactivity Info 
   TI
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CP0497647
 Compound Info 
N,N-dimethyl-1-(10-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)methanamine
   Show/Hide
C20H24N2O
  1
1
IC50 = 10.47 nM
 Bioactivity Info 
   TI
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   LO
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CP0091879
 Compound Info 
1-(9,17-difluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7(12),8,10,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H20F2N2O
  1
1
IC50 = 10.72 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0183894
 Compound Info 
N-methyl-1-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
   Show/Hide
C18H20N2O
  1
1
IC50 = 13.18 nM
 Bioactivity Info 
   TI
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   LO
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CP0467988
 Compound Info 
3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethanamine
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C17H18N2O
  1
1
IC50 = 15.85 nM
 Bioactivity Info 
   TI
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CP0431008
 Compound Info 
N,N-dimethyl-1-(17-phenyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)methanamine
   Show/Hide
C25H26N2O
  1
1
IC50 = 22.39 nM
 Bioactivity Info 
   TI
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CP0734983
 Compound Info 
Dimethyl-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-ylmethyl)-amine
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C19H22N2O
  1
1
IC50 = 22.91 nM
 Bioactivity Info 
   TI
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CP0453941
 Compound Info 
1-(15-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21FN2O
  1
1
IC50 = 23.99 nM
 Bioactivity Info 
   TI
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CP0384022
 Compound Info 
4-(pyrrolidin-1-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
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C21H24N2O
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
   TI
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CP0405608
 Compound Info 
1-(11-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21FN2O
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
   TI
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   LO
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CP0497667
 Compound Info 
1-(18-chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21ClN2O
  1
1
IC50 = 32.36 nM
 Bioactivity Info 
   TI
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   LO
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CP0402198
 Compound Info 
N-ethyl-N-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)ethanamine
   Show/Hide
C21H26N2O
  1
1
IC50 = 42.66 nM
 Bioactivity Info 
   TI
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CP0435998
 Compound Info 
N,N-dimethyl-1-(8-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
   Show/Hide
C20H24N2O
  1
1
IC50 = 47.86 nM
 Bioactivity Info 
   TI
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CP0464753
 Compound Info 
1-(9-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21FN2O
  1
1
IC50 = 53.7 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0392920
 Compound Info 
N,N-dimethyl-1-[8-(trifluoromethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H21F3N2O
  1
1
IC50 = 67.61 nM
 Bioactivity Info 
   TI
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   LO
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CP0094561
 Compound Info 
N,N-dimethyl-2-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)ethanamine
   Show/Hide
C20H24N2O
  1
1
IC50 = 91.2 nM
 Bioactivity Info 
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   LO
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CP0464885
 Compound Info 
N,N-dimethyl-1-(15-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
   Show/Hide
C20H24N2O
  1
1
IC50 = 91.2 nM
 Bioactivity Info 
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CP0475727
 Compound Info 
4-(morpholin-4-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
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C21H24N2O2
  1
1
IC50 = 141.25 nM
 Bioactivity Info 
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CP0421446
 Compound Info 
4-[(4-methylpiperazin-1-yl)methyl]-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
   Show/Hide
C22H27N3O
  1
1
IC50 = 281.84 nM
 Bioactivity Info 
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CP0372936
 Compound Info 
1-(9-methoxy-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C20H24N2O2
  1
1
IC50 = 302 nM
 Bioactivity Info 
   TI
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   LO
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CP0404509
 Compound Info 
N,N-dimethyl-1-[11-(trifluoromethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H21F3N2O
  1
1
IC50 = 1000 nM
 Bioactivity Info 
   TI
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CP0392599
 Compound Info 
N-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)-N-propan-2-ylpropan-2-amine
   Show/Hide
C23H30N2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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   LO
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CP0422415
 Compound Info 
4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
   Show/Hide
C27H28ClN3O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0437491
 Compound Info 
2,2,2-trifluoro-N-methyl-N-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)acetamide
   Show/Hide
C20H19F3N2O2
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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   LO
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CP0460072
 Compound Info 
N,N-dimethyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene-4-carboxamide
   Show/Hide
C19H20N2O2
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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CP0461043
 Compound Info 
4-[(4-phenylpiperazin-1-yl)methyl]-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
   Show/Hide
C27H29N3O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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CP0461320
 Compound Info 
2-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)isoindole-1,3-dione
   Show/Hide
C25H20N2O3
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463614
 Compound Info 
N,N-dimethyl-4-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)butan-1-amine
   Show/Hide
C22H28N2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
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CP0464735
 Compound Info 
4-(piperazin-1-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
   Show/Hide
C21H25N3O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
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CP0476618
 Compound Info 
4-(1,3-dihydroisoindol-2-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
   Show/Hide
C25H24N2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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CP0383066
 Compound Info 
1-(11-chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21ClN2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0508933
 Compound Info 
1-(8-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
   Show/Hide
C19H21FN2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
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CP0515871
 Compound Info 
N,N-dimethyl-1-[9-(trifluoromethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H21F3N2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
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CP0050128
 Compound Info 
N,N-dimethyl-1-[(2S,4R,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H23NO
  1
1
Ki = 2.5 nM
 Bioactivity Info 
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CP0530334
 Compound Info 
N,N-dimethyl-1-[(4S,6R)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C19H22N2O
  1
1
Ki = 2.5 nM
 Bioactivity Info 
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CP0319460
 Compound Info 
((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
   Show/Hide
C19H20BrNO2
  1
1
Ki = 3 nM
 Bioactivity Info 
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CP0311945
 Compound Info 
((2S,3aS,12bS)-11-Chloro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
   Show/Hide
C19H20ClNO2
  1
1
Ki = 5 nM
 Bioactivity Info 
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   LO
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CP0251195
 Compound Info 
((2R,3aS,12bS)-11-Chloro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
   Show/Hide
C19H20ClNO2
  1
1
Ki = 11 nM
 Bioactivity Info 
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CP0716967
 Compound Info 
Dimethyl-[(2R,3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-yl)methyl]-amine
   Show/Hide
C19H21NO2
  1
1
Ki = 16 nM
 Bioactivity Info 
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CP0461357
 Compound Info 
1-Methyl-4-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-yl)methyl]-piperazine
   Show/Hide
C22H26N2OS
  1
1
Ki = 17.3 nM
 Bioactivity Info 
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CP0422236
 Compound Info 
N,N-dimethyl-1-[(2S,4S,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H23NO
  1
1
Ki = 19.6 nM
 Bioactivity Info 
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CP0478245
 Compound Info 
N,N-dimethyl-1-[(2S,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H23NO
  1
1
Ki = 21.7 nM
 Bioactivity Info 
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CP0366089
 Compound Info 
((2S,3aS,12bS)-11-Methoxy-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
   Show/Hide
C20H23NO3
  1
1
Ki = 22 nM
 Bioactivity Info 
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CP0454651
 Compound Info 
N,N-dimethyl-1-[(2S,6R)-3-oxa-13-thiatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C19H21NOS
  1
1
Ki = 30.7 nM
 Bioactivity Info 
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   LO
   TS
CP0275194
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-3-methyl-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-triene
   Show/Hide
C24H20BrNO3
  1
1
Ki = 36 nM
 Bioactivity Info 
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CP0454625
 Compound Info 
1-[(2S,6R)-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]-N,N-dimethylmethanamine
   Show/Hide
C19H21NO2
  1
1
Ki = 37 nM
 Bioactivity Info 
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CP0448928
 Compound Info 
N-methyl-1-[(2S,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C19H21NO
  1
1
Ki = 48.6 nM
 Bioactivity Info 
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CP0470578
 Compound Info 
1-(3-Chloro-phenyl)-4-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazine
   Show/Hide
C28H29ClN2O
  1
1
Ki = 56 nM
 Bioactivity Info 
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   TS
CP0077877
 Compound Info 
((2R,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
   Show/Hide
C19H20BrNO2
  1
1
Ki = 65 nM
 Bioactivity Info 
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CP0438782
 Compound Info 
4-Phenyl-1-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-yl)methyl]-piperidine
   Show/Hide
C28H29NOS
  1
1
Ki = 68.7 nM
 Bioactivity Info 
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CP0453367
 Compound Info 
N-methyl-1-[(2R,4S,6S)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
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C19H21NO
  1
1
Ki = 74.1 nM
 Bioactivity Info 
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CP0438192
 Compound Info 
N,N-dimethyl-1-[(2S,6R)-13-methyl-3-oxa-13-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
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C20H24N2O
  1
1
Ki = 80.7 nM
 Bioactivity Info 
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CP0457342
 Compound Info 
2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazin-1-yl}-ethanol
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C24H30N2O2
  1
1
Ki = 86.5 nM
 Bioactivity Info 
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CP0438554
 Compound Info 
1-[(2S,6R)-3,13-dioxatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),7,9,11,15,17-hexaen-4-yl]-N,N-dimethylmethanamine
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C20H23NO2
  1
1
Ki = 90.5 nM
 Bioactivity Info 
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CP0035139
 Compound Info 
1-[(2R,4R,6S)-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]-N,N-dimethylmethanamine
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C19H21NO2
  1
1
Ki = 92 nM
 Bioactivity Info 
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CP0463465
 Compound Info 
1-[(2S,6S)-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]-N,N-dimethylmethanamine
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C19H21NO2
  1
1
Ki = 92.6 nM
 Bioactivity Info 
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CP0312008
 Compound Info 
8-[[(2S,4S,6S)-17-bromo-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl]methyl]-N,N-dimethyl-7-oxa-8-azabicyclo[4.2.0]octa-1(6),2,4-trien-3-amine
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C25H23BrN2O3
  1
1
Ki = 95 nM
 Bioactivity Info 
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CP0077886
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-triene-3-carboxylic acid ethyl ester
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C26H22BrNO5
  1
1
Ki = 97 nM
 Bioactivity Info 
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CP0448518
 Compound Info 
N,N-dimethyl-1-[(2S,6S)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
   Show/Hide
C20H23NO
  1
1
Ki = 102 nM
 Bioactivity Info 
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CP0250615
 Compound Info 
((2S,3aS,12bS)-11-Fluoro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
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C19H20FNO2
  1
1
Ki = 104 nM
 Bioactivity Info 
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CP0420430
 Compound Info 
N,N-dimethyl-1-[(2R,4S,6S)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
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C20H23NO
  1
1
Ki = 104 nM
 Bioactivity Info 
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CP0237838
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-triene-3-carbonitrile
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C24H17BrN2O3
  1
1
Ki = 185 nM
 Bioactivity Info 
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CP0254576
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-3-morpholin-4-ylmethyl-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-triene
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C28H27BrN2O4
  1
1
Ki = 189 nM
 Bioactivity Info 
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CP0319461
 Compound Info 
((2R,3aS,12bS)-11-Methoxy-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
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C20H23NO3
  1
1
Ki = 193 nM
 Bioactivity Info 
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CP0092119
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-trien-3-ylamine
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C23H19BrN2O3
  1
1
Ki = 255 nM
 Bioactivity Info 
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CP0077915
 Compound Info 
1-[8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-trien-3-yl]-azetidin-2-one
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C26H21BrN2O4
  1
1
Ki = 306 nM
 Bioactivity Info 
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CP0408686
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-3-morpholin-4-yl-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-triene
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C27H25BrN2O4
  1
1
Ki = 306 nM
 Bioactivity Info 
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CP0160384
 Compound Info 
8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-3-phenyl-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-triene
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C29H22BrNO3
  1
1
Ki = 307 nM
 Bioactivity Info 
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CP0146501
 Compound Info 
((2R,3aS,12bS)-11-Fluoro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine
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C19H20FNO2
  1
1
Ki = 423 nM
 Bioactivity Info 
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CP0383041
 Compound Info 
4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-morpholine
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C22H25NO2
  1
1
Ki = 433 nM
 Bioactivity Info 
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CP0401076
 Compound Info 
1-Methyl-4-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazine
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C23H28N2O
  1
1
Ki = 433 nM
 Bioactivity Info 
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CP0403652
 Compound Info 
(4-Fluoro-phenyl)-{1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperidin-4-yl}-methanone
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C30H30FNO2
  1
1
Ki = 433 nM
 Bioactivity Info 
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CP0461004
 Compound Info 
1-[(2S,6R)-3,14-dioxatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),7,9,11,15,17-hexaen-4-yl]-N,N-dimethylmethanamine
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C20H23NO2
  1
1
Ki = 1064 nM
 Bioactivity Info 
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CP0480878
 Compound Info 
4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperidine
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C29H31NO
  1
1
Ki = 1088 nM
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Protein ID: PT01577, Androgen receptor
 Protein Info 
Protein ID: PT05510, Cell death protein RIP
 Protein Info 
Protein ID: PT00897, Eag homolog
 Protein Info 
Protein ID: PT00967, Glucocorticoid receptor
 Protein Info 
Protein ID: PT02751, Glutamate receptor ionotropic, NMDA 2B
 Protein Info 
Protein ID: PT02298, HGK5
 Protein Info 
Protein ID: PT06097, Inward rectifier K(+) channel Kir6.2
 Protein Info 
Protein ID: PT01325, Melanocortin receptor 3
 Protein Info 
Protein ID: PT00914, Melanocortin receptor 4
 Protein Info 
Protein ID: PT01804, Melanocortin receptor 5
 Protein Info 
Protein ID: PT00911, Melanocyte-stimulating hormone receptor
 Protein Info 
Protein ID: PT02199, Metabotropic glutamate receptor 4
 Protein Info 
Protein ID: PT04787, Protein-serine O-palmitoleoyltransferase porcupine
 Protein Info 
Protein ID: PT04857, Proto-oncogene Wnt-3
 Protein Info 
Protein ID: PT02347, Tumor necrosis factor
 Protein Info 
Protein ID: PT02768, Voltage-gated potassium channel HK2
 Protein Info 
Protein ID: PT05966, Voltage-gated potassium channel subunit Kv1.3
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0023959
 Compound Info 
(-)-Epigallocatechin gallate
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 C22H18O11  1
1
IC50 = 82300 nM
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CP0036222
 Compound Info 
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
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 C62H111N11O12  1
1
IC50 = 30000 nM
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CP0036382
 Compound Info 
CAS_52-53-9
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 C27H38N2O4  3
1
IC50 = 88000 nM
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2
IC50 = 89000 nM
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3
IC50 = 89200 nM
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CP0049207
 Compound Info 
(S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propylamino]-benzoylamino}-pentanedioic acid
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 C19H24N6O6  1
1
IC50 = 88 nM
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CP0078757
 Compound Info 
(E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(3-(dimethylamino)-3-oxopropylthio)methylthio)propanoic acid
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 C26H27ClN2O3S2  1
1
IC50 > 100000 nM
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CP0376149
 Compound Info 
(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-ol
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 C20H24O7  1
1
IC50 > 100000 nM
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CP0376150
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] (E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate
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 C32H36O11  1
1
IC50 > 100000 nM
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CP0376714
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3-[(3,4-dimethoxybenzoyl)amino]-4-fluorobenzoate
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 C36H36FNO11  1
1
IC50 > 100000 nM
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CP0381563
 Compound Info 
1,16-Bis[40-((6-methyl)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13,16-hexaoxahexadecane
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 C42H42O10  1
1
IC50 > 100000 nM
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CP0385379
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] (E)-3-(3,4-dimethoxyphenyl)prop-2-enoate
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 C31H34O10  1
1
IC50 > 100000 nM
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CP0392213
 Compound Info 
7-[2-[[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]methoxy]ethoxy]-2-phenylchromen-4-one
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 C39H33N3O8  1
1
IC50 > 50000 nM
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CP0392214
 Compound Info 
7-[3-[1-[2-[2-(4-oxo-2-phenylchromen-7-yl)oxyethoxy]ethyl]triazol-4-yl]propoxy]-2-phenylchromen-4-one
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 C39H33N3O7  1
1
IC50 > 100000 nM
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CP0392220
 Compound Info 
6-methyl-2-[4-[4-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]butoxy]phenyl]chromen-4-one
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 C41H37N3O7  1
1
IC50 > 57000 nM
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CP0394430
 Compound Info 
7-[2-[benzyl-[[1-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
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 C46H39FN4O7  1
1
IC50 > 100000 nM
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CP0400853
 Compound Info 
[(2R,3S)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3-[(3,4-dimethoxybenzoyl)amino]-4-fluorobenzoate
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 C36H36FNO11  1
1
IC50 > 100000 nM
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CP0411926
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 4-methoxybenzoate
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 C28H30O9  1
1
IC50 > 100000 nM
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CP0413620
 Compound Info 
N-[5-[[4-(diethylamino)phenyl]methyl]-4-[(3,4-dimethoxyphenyl)methyl]-1-methylimidazol-2-yl]-3,4,5-trimethoxybenzamide
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 C34H42N4O6  1
1
IC50 = 47400 nM
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CP0426779
 Compound Info 
2-[4-[4-[1-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]butoxy]phenyl]-6-methylchromen-4-one
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 C41H36FN3O7  1
1
IC50 > 100000 nM
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CP0433607
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]-4-fluorobenzoate
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 C38H38FNO11  1
1
IC50 > 100000 nM
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CP0433749
 Compound Info 
[(2R,3S)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 4-fluoro-3-[(3,4,5-trimethoxybenzoyl)amino]benzoate
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 C37H38FNO12  1
1
IC50 > 100000 nM
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CP0437292
 Compound Info 
7-[2-[benzyl-[[1-[2-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
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 C48H43FN4O8  1
1
IC50 > 100000 nM
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CP0444644
 Compound Info 
[(2R,3S)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] (E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate
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 C32H36O11  1
1
IC50 > 100000 nM
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CP0449125
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4-dimethoxybenzoate
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 C29H32O10  1
1
IC50 > 100000 nM
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CP0455369
 Compound Info 
7-[4-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]butoxy]-2-phenylchromen-4-one
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 C40H35N3O7  1
1
IC50 > 100000 nM
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CP0457483
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3-(dimethylamino)-4-fluorobenzoate
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 C29H32FNO8  1
1
IC50 > 100000 nM
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CP0499273
 Compound Info 
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 4-fluoro-3-[[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]amino]benzoate
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 C39H40FNO12  1
1
IC50 > 100000 nM
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CP0562097
 Compound Info 
N-phenyl-N'-trityloxyoctanediamide
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 C33H34N2O3  1
1
CC50 > 100000 nM
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CP0847075
 Compound Info 
(2R,3S)-5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)chroman-3-yl 3-((E)-3-(3,4-dimethoxyphenyl)acrylamido)-4-fluorobenzoate
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 C38H38FNO11  1
1
IC50 > 100000 nM
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CP0849538
 Compound Info 
(2R,3R)-5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)chroman-3-yl 3-acetamido-4-fluorobenzoate
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 C29H30FNO9  1
1
IC50 > 100000 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Connective tissue)
Cell Line Name Organism Disease
human L929
 Cell Line Info 
Homo sapiens (Human) -
LTK-
 Cell Line Info 
Mus musculus (Mouse) -
L-M(TK-)
 Cell Line Info 
Mus musculus (Mouse) -
A-9
 Cell Line Info 
Mus musculus (Mouse) -
L Wnt-3A
 Cell Line Info 
Mus musculus (Mouse) -
LAP1
 Cell Line Info 
Mus musculus (Mouse) -
LV2
 Cell Line Info 
Mus musculus (Mouse) -