Brief Information of the Cell Line and Protein
Cell Line ID: CL000309 , NCTC clone 929
Synonyms
NCTC 929
NCTC-929
NCTC929
NCTC-929L
L cell
L cells
L-cell
L-cells
L cell line
L
Strain L-929
L-929
L 929
L929
L929(NCTC)
Clone 929
Earles's cells
Earle's L cells
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0462
Protein ID: PT06097 , ATP-sensitive inward rectifier potassium channel 11
Gene Name KCNJ11
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q14654
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000309  Protein ID: PT06097
 
Compound ID Compound Name Compound Formula
CP0535354
4-chloro-N-[(1S)-2,2-dichloro-1-[[(cyanoamino)-(pyridin-3-ylamino)methylidene]amino]propyl]benzamide
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C17H15Cl3N6O
 1
1
EC50 = 338.84 nM
   TI
   LI
   LO
   TS
CP0009479
ZD 6169
   Show/Hide
C17H14F3NO3
 1
1
EC50 = 436.52 nM
   TI
   LI
   LO
   TS
CP0565464
4-chloro-N-[2,2-dichloro-1-[(E)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl4N6O
 1
1
EC50 = 457.09 nM
   TI
   LI
   LO
   TS
CP0522267
4-bromo-N-[2,2-dichloro-1-[(E)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H14BrCl3N6O
 1
1
EC50 = 537.03 nM
   TI
   LI
   LO
   TS
CP0565463
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-4-chlorobenzamide
   Show/Hide
C17H14BrCl3N6O
 1
1
EC50 = 645.65 nM
   TI
   LI
   LO
   TS
CP0524512
4-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(5-methylpyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H17Cl3N6O
 1
1
EC50 = 758.58 nM
   TI
   LI
   LO
   TS
CP0537570
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-3-chlorobenzamide
   Show/Hide
C17H14BrCl3N6O
 1
1
EC50 = 776.25 nM
   TI
   LI
   LO
   TS
CP0524511
3,5-dichloro-N-[2,2-dichloro-1-[[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H13Cl5N6O
 1
1
EC50 = 812.83 nM
   TI
   LI
   LO
   TS
CP0496666
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-4-iodobenzamide
   Show/Hide
C17H14Cl3IN6O
 1
1
EC50 = 891.25 nM
   TI
   LI
   LO
   TS
CP0542193
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-4-methylbenzamide
   Show/Hide
C18H17Cl3N6O
 1
1
EC50 = 912.01 nM
   TI
   LI
   LO
   TS
CP0535366
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-4-fluorobenzamide
   Show/Hide
C17H14BrCl2FN6O
 1
1
EC50 = 954.99 nM
   TI
   LI
   LO
   TS
CP0501254
4-chloro-N-[(1S)-2,2-dichloro-1-[(E)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl4N6O
 1
1
EC50 = 1071.52 nM
   TI
   LI
   LO
   TS
CP0497535
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-3,5-difluorobenzamide
   Show/Hide
C17H13BrCl2F2N6O
 1
1
EC50 = 1096.48 nM
   TI
   LI
   LO
   TS
CP0542172
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-3,5-difluorobenzamide
   Show/Hide
C17H13Cl3F2N6O
 1
1
EC50 = 1096.48 nM
   TI
   LI
   LO
   TS
CP0530306
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-3,5-difluorobenzamide
   Show/Hide
C18H13Cl2F5N6O
 1
1
EC50 = 1174.9 nM
   TI
   LI
   LO
   TS
CP0424320
N-[2,2-dichloro-1-[[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-4-fluorobenzamide
   Show/Hide
C17H14Cl3FN6O
 1
1
EC50 = 1288.25 nM
   TI
   LI
   LO
   TS
CP0535365
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]thiophene-2-carboxamide
   Show/Hide
C15H13BrCl2N6OS
 1
1
EC50 = 1288.25 nM
   TI
   LI
   LO
   TS
CP0522270
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-4-methylbenzamide
   Show/Hide
C18H17BrCl2N6O
 1
1
EC50 = 1318.26 nM
   TI
   LI
   LO
   TS
CP0463055
4-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl3FN6O
 1
1
EC50 = 1513.56 nM
   TI
   LI
   LO
   TS
CP0501748
4-chloro-N-[2,2-dichloro-1-[[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H14Cl3F3N6O
 1
1
EC50 = 1621.81 nM
   TI
   LI
   LO
   TS
CP0535364
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-3-methylbenzamide
   Show/Hide
C18H17BrCl2N6O
 1
1
EC50 = 1659.59 nM
   TI
   LI
   LO
   TS
CP0565524
3-chloro-N-[2,2-dichloro-1-[[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl4N6O
 1
1
EC50 = 1659.59 nM
   TI
   LI
   LO
   TS
CP0510951
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-3-methylbenzamide
   Show/Hide
C18H17Cl3N6O
 1
1
EC50 = 1698.24 nM
   TI
   LI
   LO
   TS
CP0542169
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]thiophene-2-carboxamide
   Show/Hide
C16H13Cl2F3N6OS
 1
1
EC50 = 1737.8 nM
   TI
   LI
   LO
   TS
CP0528592
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H15Cl3N6O
 1
1
EC50 = 2041.74 nM
   TI
   LI
   LO
   TS
CP0539678
3,5-dichloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C17H13Cl4FN6O
 1
1
EC50 = 2041.74 nM
   TI
   LI
   LO
   TS
CP0421964
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-4-fluorobenzamide
   Show/Hide
C18H14Cl2F4N6O
 1
1
EC50 = 2089.3 nM
   TI
   LI
   LO
   TS
CP0505403
4-chloro-N-[(1R)-2,2-dichloro-1-[(E)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl4N6O
 1
1
EC50 = 2137.96 nM
   TI
   LI
   LO
   TS
CP0542195
4-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-methylpyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H17Cl3N6O
 1
1
EC50 = 2238.72 nM
   TI
   LI
   LO
   TS
CP0509409
3-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl3FN6O
 1
1
EC50 = 2290.87 nM
   TI
   LI
   LO
   TS
CP0530305
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-3-fluorobenzamide
   Show/Hide
C18H14Cl2F4N6O
 1
1
EC50 = 2290.87 nM
   TI
   LI
   LO
   TS
CP0428494
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-3-methylbenzamide
   Show/Hide
C19H17Cl2F3N6O
 1
1
EC50 = 2570.4 nM
   TI
   LI
   LO
   TS
CP0530304
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-3,5-dichlorobenzamide
   Show/Hide
C17H13BrCl4N6O
 1
1
EC50 = 2630.27 nM
   TI
   LI
   LO
   TS
CP0542171
N-[2,2-dichloro-1-[(E)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]thiophene-2-carboxamide
   Show/Hide
C15H13Cl3N6OS
 1
1
EC50 = 2754.23 nM
   TI
   LI
   LO
   TS
CP0542168
3,5-dichloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H13Cl4F3N6O
 1
1
EC50 = 3715.35 nM
   TI
   LI
   LO
   TS
CP0497536
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-4-methylbenzamide
   Show/Hide
C19H17Cl2F3N6O
 1
1
EC50 = 3801.89 nM
   TI
   LI
   LO
   TS
CP0463117
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]-3-methylbenzamide
   Show/Hide
C18H17Cl2FN6O
 1
1
EC50 = 4265.8 nM
   TI
   LI
   LO
   TS
CP0501280
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]-3,5-difluorobenzamide
   Show/Hide
C17H13Cl2F3N6O
 1
1
EC50 = 4265.8 nM
   TI
   LI
   LO
   TS
CP0539676
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]-4-methylbenzamide
   Show/Hide
C18H17Cl2FN6O
 1
1
EC50 = 4265.8 nM
   TI
   LI
   LO
   TS
CP0539677
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]thiophene-2-carboxamide
   Show/Hide
C15H13Cl2FN6OS
 1
1
EC50 = 4570.88 nM
   TI
   LI
   LO
   TS
CP0565523
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-4-(trifluoromethyl)benzamide
   Show/Hide
C18H14Cl3F3N6O
 1
1
EC50 = 5011.87 nM
   TI
   LI
   LO
   TS
CP0542170
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-3-fluorobenzamide
   Show/Hide
C17H14Cl3FN6O
 1
1
EC50 = 5370.32 nM
   TI
   LI
   LO
   TS
CP0565522
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-4-(trifluoromethoxy)benzamide
   Show/Hide
C18H14Cl3F3N6O2
 1
1
EC50 = 5370.32 nM
   TI
   LI
   LO
   TS
CP0473675
4-chloro-N-[2,2-dichloro-1-[[[(2-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]benzamide
   Show/Hide
C17H14Cl4N6O
 1
1
EC50 = 6025.6 nM
   TI
   LI
   LO
   TS
CP0537572
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-3-methoxypyridine-4-carboxamide
   Show/Hide
C17H16Cl3N7O2
 1
1
EC50 = 6606.93 nM
   TI
   LI
   LO
   TS
CP0542167
3-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H14Cl3F3N6O
 1
1
EC50 = 6760.83 nM
   TI
   LI
   LO
   TS
CP0539679
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-4-iodobenzamide
   Show/Hide
C18H14Cl2F3IN6O
 1
1
EC50 = 7762.47 nM
   TI
   LI
   LO
   TS
CP0458865
N-[2,2-dichloro-1-[(Z)-[[(6-chloropyridin-3-yl)amino]-(cyanoamino)methylidene]amino]propyl]-3,5-dimethoxybenzamide
   Show/Hide
C19H19Cl3N6O3
 1
1
EC50 = 8912.51 nM
   TI
   LI
   LO
   TS
CP0554336
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]-4-(trifluoromethoxy)benzamide
   Show/Hide
C18H14Cl2F4N6O2
 1
1
EC50 = 8912.51 nM
   TI
   LI
   LO
   TS
CP0501255
4-chloro-N-[2,2-dichloro-1-[(E)-[(cyanoamino)-[[2-methyl-6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]benzamide
   Show/Hide
C19H16Cl3F3N6O
 1
1
EC50 = 9549.93 nM
   TI
   LI
   LO
   TS
CP0435265
4-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(2-methoxypyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H17Cl3N6O2
 1
1
EC50 = 9772.37 nM
   TI
   LI
   LO
   TS
CP0463054
4-chloro-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-methoxypyridin-3-yl)amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H17Cl3N6O2
 1
1
EC50 = 10471.29 nM
   TI
   LI
   LO
   TS
CP0530303
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[(6-fluoropyridin-3-yl)amino]methylidene]amino]propyl]-4-fluorobenzamide
   Show/Hide
C17H14Cl2F2N6O
 1
1
EC50 = 11748.98 nM
   TI
   LI
   LO
   TS
CP0542194
4-chloro-N-[2,2-dichloro-1-[[(cyanoamino)-(2-fluoroanilino)methylidene]amino]propyl]benzamide
   Show/Hide
C18H15Cl3FN5O
 1
1
EC50 = 12022.64 nM
   TI
   LI
   LO
   TS
CP0535368
N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]-4-(trifluoromethyl)benzamide
   Show/Hide
C19H14Cl2F6N6O
 1
1
EC50 = 26915.35 nM
   TI
   LI
   LO
   TS
CP0424323
N-[1-[(Z)-[[(5-bromopyridin-3-yl)amino]-(cyanoamino)methylidene]amino]-2,2-dichloropropyl]-4-(trifluoromethoxy)benzamide
   Show/Hide
C18H14BrCl2F3N6O2
 1
1
EC50 < 100000 nM
   TI
   LI
   LO
   TS
CP0535367
4-bromo-N-[2,2-dichloro-1-[(Z)-[(cyanoamino)-[[6-(trifluoromethyl)pyridin-3-yl]amino]methylidene]amino]propyl]benzamide
   Show/Hide
C18H14BrCl2F3N6O
 1
1
EC50 < 100000 nM
   TI
   LI
   LO
   TS