Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
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 PubChem ID
CID: 3559
SID: 14902191
Canonical SMILES
OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
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Compound Formula C21H23ClFNO2
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P19020
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 6.4 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
Ki = 5.04 nM
   TI
   LI
   LO
   TS
2
Ki = 5.57 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
Ki = 14.3 nM
   TI
   LI
   LO
   TS
2
Ki = 18 nM
   TI
   LI
   LO
   TS
3
Ki = 47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3 nM
2 Ki = 28 nM