Cell Line ID	CL000043
Cell Line Name	U2OS
Synonyms	U-2 OS U-2OS U-2-OS U2-OS U20-S U20S 2T
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0042
Tissue Information	Bone
Disease	Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668)

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Compound ID	Compound Name	Compound Formula
CP0943397  Compound Info	SID144204511    Show/Hide	C22H23ClFN3O2S	1
1	IC50 = 1.51 nM  Bioactivity Info	TI    LI    LO    TS
CP0001238  Compound Info	14C-5-hydroxy tryptamine creatinine disulfate    Show/Hide	C10H12N2O	1
1	IC50 = 27.9 nM  Bioactivity Info	TI    LI    LO    TS
CP0531461  Compound Info	Adatanserin hydrochloride    Show/Hide	C21H32ClN5O	1
1	IC50 = 33.7 nM  Bioactivity Info	TI    LI    LO    TS
CP0420311  Compound Info	N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]adamantane-1-carbothioamide    Show/Hide	C21H31N5S	1
1	IC50 = 62.3 nM  Bioactivity Info	TI    LI    LO    TS
CP0409289  Compound Info	benzyl N-[2-(1-benzyl-4-pyrimidin-2-ylpiperazin-1-ium-1-yl)ethyl]adamantane-1-carboximidothioate;bromide    Show/Hide	C35H44BrN5S	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS
CP0548643  Compound Info	methyl N-[2-(1-methyl-4-pyrimidin-2-ylpiperazin-1-ium-1-yl)ethyl]adamantane-1-carboximidothioate;iodide    Show/Hide	C23H36IN5S	1
1	IC50 > 10000 nM  Bioactivity Info	TI    LI    LO    TS

Compound ID	Compound Name	Compound Formula
CP0092308  Compound Info	4-[2-amino-5-[4-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[(Z,2R)-5,5,5-trifluoropent-3-en-2-yl]oxybenzamide    Show/Hide	C24H25F3N4O2S	1
1	GI50 = 1820 nM	TI    LI    LO    TS
CP0114044  Compound Info	4-[2-amino-5-[4-[(dimethylamino)methyl]thiophen-2-yl]pyridin-3-yl]-2-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]benzamide    Show/Hide	C28H27F3N4O2S	1
1	GI50 = 480 nM	TI    LI    LO    TS
CP0930355  Compound Info	5-(3-Hydroxy-4-oxo-1,4-dihydroquinolin-2-yl)-2-(piperidin-1-yl)-benzamide    Show/Hide	C21H21N3O3	1
1	IC50 = 26020 nM	TI    LI    LO    TS

	Cell Line Name		Organism	Disease
	Raji	Cell Line Info	Homo sapiens (Human)	EBV-related Burkitt lymphoma
	Cheptage	Cell Line Info	Homo sapiens (Human)	EBV-related Burkitt lymphoma
	HT-1080	Cell Line Info	Homo sapiens (Human)	Fibrosarcoma
	2fTGH-U3A	Cell Line Info	Homo sapiens (Human)	Fibrosarcoma
	HT1080-luc2	Cell Line Info	Homo sapiens (Human)	Fibrosarcoma
	SaOS-2	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	G-292 clone A141B1	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	HOS	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	MG-63	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	SJSA-1	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	GHOST(3).CXCR4	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	GHOST(3).CCR5	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	143.98.2	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	GHOST(3).X4/R5	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	PathHunter U2OS DRD3 beta-arrestin	Cell Line Info	Homo sapiens (Human)	Osteosarcoma
	SW1353	Cell Line Info	Homo sapiens (Human)	Primary central chondrosarcoma
	PC-3	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
	PC-3M	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
	PC-3-AR	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
	PPC-1	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
	VCaP	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
	MDA-PCa-2b	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
	RMS13	Cell Line Info	Mus musculus (Mouse)	Mouse rhabdomyosarcoma
	UMR-106	Cell Line Info	Rattus norvegicus (Rat)	Rat osteosarcoma
	ROS 17/2.8	Cell Line Info	Rattus norvegicus (Rat)	Rat osteosarcoma
	MC3T3-E1	Cell Line Info	Mus musculus (Mouse)	-