General Information of the Cell Line
Cell Line ID
CL000174
Cell Line Name
Raji
Synonyms
RAJI
P1-Raji
GM04671
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0511
Tissue Information
Bone
Disease
EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01462, Bromodomain-containing protein 4
 Protein Info 
Compound ID Compound Name Compound Formula
CP0335216
 Compound Info 
4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1-methylpyrazol-4-yl)isoquinolin-1-one
   Show/Hide
C25H27N3O4S
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
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CP0335218
 Compound Info 
4-(2-ethoxy-5-ethylsulfonylphenyl)-2-methyl-6-(1-methylpyrazol-4-yl)isoquinolin-1-one
   Show/Hide
C24H25N3O4S
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
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CP0103451
 Compound Info 
2-methyl-6-(1-methylpyrazol-4-yl)-4-(5- methylsulfonyl-2- propoxyphenyl)isoquinolin-1-one
   Show/Hide
C24H25N3O4S
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
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CP0368318
 Compound Info 
4-(2-ethoxy-5-methylsulfonylphenyl)-2- methyl-6-(1-methylpyrazol-4- yl)isoquinolin-1-one
   Show/Hide
C23H23N3O4S
  1
1
IC50 = 24 nM
 Bioactivity Info 
   TI
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CP0004236
 Compound Info 
(+)-JQ1
   Show/Hide
C23H25ClN4O2S
  2
1
IC50 = 60 nM
 Bioactivity Info 
   TI
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2
IC50 = 69 nM
 Bioactivity Info 
   TI
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CP0335215
 Compound Info 
4-(5-ethylsulfonyl-2-methoxyphenyl)-2- methyl-6-(1-methylpyrazol-4-yl)isoquinolin- 1-one
   Show/Hide
C23H23N3O4S
  1
1
IC50 = 65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071180
 Compound Info 
2-[(9S)-7-(4-cyanophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C21H18N4O2S
  1
1
IC50 = 91 nM
 Bioactivity Info 
   TI
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CP0410254
 Compound Info 
N-[3-[2-methyl-6-(1-methylpyrazol-4-yl)-1- oxoisoquinolin-4-yl] phenyl]methanesulfonamide
   Show/Hide
C21H20N4O3S
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
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CP0057034
 Compound Info 
7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one
   Show/Hide
C23H21N5O3
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
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CP0036210
 Compound Info 
2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide
   Show/Hide
C22H22ClN5O2
  2
1
IC50 = 132 nM
 Bioactivity Info 
   TI
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2
IC50 = 190 nM
 Bioactivity Info 
   TI
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   TS
CP0109050
 Compound Info 
2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C20H18ClN3O2S
  1
1
IC50 = 140 nM
 Bioactivity Info 
   TI
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CP0575021
 Compound Info 
4-[5-ethylsulfonyl-2-(2- hydroxyethoxy)phenyl]-2-methyl-6-(1- methylpyrazol-4-yl)isoquinolin-1-one
   Show/Hide
C24H25N3O5S
  1
1
IC50 = 150 nM
 Bioactivity Info 
   TI
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CP0153327
 Compound Info 
2-[(9S)-7-(4-chloro-2-methylphenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C21H20ClN3O2S
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
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CP0248859
 Compound Info 
2-[(9S)-4,5,13-trimethyl-7-phenyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C20H19N3O2S
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
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CP0462117
 Compound Info 
2-[(9S)-7-(5-chloropyridin-2-yl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C19H17ClN4O2S
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
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CP0210886
 Compound Info 
2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]-N-ethylacetamide
   Show/Hide
C22H22ClN3O2S
  1
1
IC50 = 320 nM
 Bioactivity Info 
   TI
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CP0240428
 Compound Info 
4-(3-ethylsulfonylphenyl)-2-methyl-6-(1- methylpyrazol-4-yl)isoquinolin-1-one
   Show/Hide
C22H21N3O3S
  1
1
IC50 = 368 nM
 Bioactivity Info 
   TI
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CP0084888
 Compound Info 
2-[(9S)-7-(6-aminopyridin-3-yl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C19H19N5O2S
  1
1
IC50 = 380 nM
 Bioactivity Info 
   TI
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CP0574202
 Compound Info 
2-[(9S)-7-(3-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C20H18ClN3O2S
  1
1
IC50 = 470 nM
 Bioactivity Info 
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CP0073928
 Compound Info 
(2R)-2-[(9S)-7-(4-cyanophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]propanamide
   Show/Hide
C22H20N4O2S
  1
1
IC50 = 710 nM
 Bioactivity Info 
   TI
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CP0336245
 Compound Info 
2-[(9S)-4,5,13-trimethyl-7-propyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C17H21N3O2S
  1
1
IC50 = 1500 nM
 Bioactivity Info 
   TI
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   TS
CP0073926
 Compound Info 
2-[(9S)-7-(2-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetamide
   Show/Hide
C20H18ClN3O2S
  1
1
IC50 = 1900 nM
 Bioactivity Info 
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CP0414322
 Compound Info 
methyl N-[[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]methyl]carbamate
   Show/Hide
C21H20ClN3O3S
  1
1
IC50 = 1900 nM
 Bioactivity Info 
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CP0087167
 Compound Info 
(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-9-(1,3-thiazol-2-ylmethyl)-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaene
   Show/Hide
C22H18ClN3OS2
  1
1
IC50 = 2100 nM
 Bioactivity Info 
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CP0210887
 Compound Info 
tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]acetate
   Show/Hide
C24H25ClN2O3S
  1
1
IC50 = 2100 nM
 Bioactivity Info 
   TI
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CP0248951
 Compound Info 
N-[[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaen-9-yl]methyl]acetamide
   Show/Hide
C21H20ClN3O2S
  1
1
IC50 = 2200 nM
 Bioactivity Info 
   TI
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CP0121406
 Compound Info 
(9S)-7-(4-chlorophenyl)-9-(1H-imidazol-2-ylmethyl)-4,5,13-trimethyl-11-oxa-3-thia-8,12-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,7,12-pentaene
   Show/Hide
C22H19ClN4OS
  1
1
IC50 = 3600 nM
 Bioactivity Info 
   TI
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CP0340722
 Compound Info 
4-[2-(2-aminoethoxy)-5-ethylsulfonylphenyl]- 2-methyl-6-(1-methylpyrazol-4-yl) isoquinolin-1-one
   Show/Hide
C24H26N4O4S
  1
1
IC50 = 8261 nM
 Bioactivity Info 
   TI
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Protein ID: PT01006, Cathepsin S
 Protein Info 
Protein ID: PT02563, Methylated-DNA--protein-cysteine methyltransferase
 Protein Info 
Protein ID: PT00969, Monocarboxylate transporter 1
 Protein Info 
Protein ID: PT00999, PIK3CD
 Protein Info 
Protein ID: PT02583, Proteasome subunit beta type-1
 Protein Info 
Protein ID: PT03496, Proteasome subunit beta type-10
 Protein Info 
Protein ID: PT02579, Proteasome subunit beta type-2
 Protein Info 
Protein ID: PT02585, Proteasome subunit beta type-5
 Protein Info 
Protein ID: PT03168, Proteasome subunit beta type-8
 Protein Info 
Protein ID: PT03838, Proteasome subunit beta type-9
 Protein Info 
Protein ID: PT01308, Tyrosine-protein kinase BTK
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0007430
 Compound Info 
IBRUTINIB
   Show/Hide
 C25H24N6O2  3
1
IC50 = 14200 nM
   TI
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2
IC50 = 19300 nM
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3
IC50 = 19500 nM
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CP0013015
 Compound Info 
N-[4-(2-oxo-8-pyridin-3-yl-[1]benzofuro[3,2-b]pyridin-1-yl)phenyl]prop-2-enamide
   Show/Hide
 C25H17N3O3  1
1
IC50 = 5200 nM
   TI
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CP0031672
 Compound Info 
N-[4-[8-(6-methoxypyridin-3-yl)-2-oxo-[1]benzofuro[3,2-b]pyridin-1-yl]phenyl]-2-morpholin-4-ylacetamide
   Show/Hide
 C29H26N4O5  1
1
IC50 = 13200 nM
   TI
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   TS
CP0032295
 Compound Info 
N-[4-[8-(6-methoxypyridin-3-yl)-2-oxo-[1]benzofuro[3,2-b]pyridin-1-yl]phenyl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
 C30H29N5O4  1
1
IC50 = 9720 nM
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CP0120515
 Compound Info 
4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one
   Show/Hide
 C24H23FN4O3  1
1
IC50 > 50000 nM
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CP0129819
 Compound Info 
3-[cyclopropanecarbonyl(ethyl)amino]-5-[6-[4-(cyclopropylmethyl)piperazin-1-yl]-2-methylpyridin-3-yl]-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methylbenzamide
   Show/Hide
 C36H46N6O3  1
1
GI50 > 10000 nM
   TI
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CP0322301
 Compound Info 
N-[3-[[4-[4-(piperidine-1-carbonyl)anilino]-1,3,5-triazin-2-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C24H25N7O2  1
1
IC50 = 5140 nM
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CP0335218
 Compound Info 
4-(2-ethoxy-5-ethylsulfonylphenyl)-2-methyl-6-(1-methylpyrazol-4-yl)isoquinolin-1-one
   Show/Hide
 C24H25N3O4S  1
1
IC50 = 2 nM
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CP0340722
 Compound Info 
4-[2-(2-aminoethoxy)-5-ethylsulfonylphenyl]- 2-methyl-6-(1-methylpyrazol-4-yl) isoquinolin-1-one
   Show/Hide
 C24H26N4O4S  1
1
IC50 = 11000 nM
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CP0392418
 Compound Info 
3-[5-[(E)-[(3,4,5-trimethoxybenzoyl)hydrazinylidene]methyl]furan-2-yl]benzoic acid
   Show/Hide
 C22H20N2O7  1
1
IC50 = 38000 nM
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CP0409603
 Compound Info 
3-[5-[(E)-(1H-indole-5-carbonylhydrazinylidene)methyl]furan-2-yl]benzoic acid
   Show/Hide
 C21H15N3O4  1
1
IC50 = 115000 nM
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CP0411587
 Compound Info 
N-[3-[[5-chloro-2-[4-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C26H29ClN6O3  1
1
IC50 = 9320 nM
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CP0447832
 Compound Info 
ethyl 2-[3-[(3-fluorobenzoyl)amino]phenyl]-4-[4-(4-methylpiperazin-1-yl)anilino]-1,3-thiazole-5-carboxylate
   Show/Hide
 C30H30FN5O3S  1
1
IC50 = 21240 nM
   TI
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CP0450972
 Compound Info 
N-[3-[[5-chloro-2-[2-methyl-4-[3-(4-methylpiperazin-1-yl)propoxy]anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C28H34ClN7O2  1
1
IC50 = 25000 nM
   TI
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CP0451318
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N,N-dipropylcarbamodithioate
   Show/Hide
 C28H33FN6O2S2  1
1
IC50 > 40000 nM
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CP0452683
 Compound Info 
2-(3-benzamidophenyl)-4-[4-(4-methylpiperazin-1-yl)anilino]-1,3-thiazole-5-carboxamide
   Show/Hide
 C28H28N6O2S  1
1
IC50 = 6360 nM
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CP0452685
 Compound Info 
2-[3-[(4-fluorobenzoyl)amino]phenyl]-4-[4-(morpholine-4-carbonyl)anilino]-1,3-thiazole-5-carboxamide
   Show/Hide
 C28H24FN5O4S  1
1
IC50 = 35360 nM
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CP0464545
 Compound Info 
2-[[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]amino]acetic acid
   Show/Hide
 C23H21ClN6O5  1
1
IC50 > 40000 nM
   TI
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CP0466449
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-ethylcarbamodithioate
   Show/Hide
 C24H25FN6O2S2  1
1
IC50 = 8640 nM
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CP0466450
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl 4-benzylpiperazine-1-carbodithioate
   Show/Hide
 C33H34FN7O2S2  1
1
IC50 > 40000 nM
   TI
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CP0471890
 Compound Info 
N-[3-[[5-chloro-2-[4-[(4-fluorophenyl)sulfonylamino]-3-methylanilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C26H22ClFN6O3S  1
1
IC50 = 10500 nM
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CP0478757
 Compound Info 
N-[3-[[5-fluoro-2-[3-methoxy-4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C26H27FN6O5  1
1
IC50 = 11160 nM
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CP0481300
 Compound Info 
N-[3-[[2-[4-[[2-[bis(2-methoxyethyl)amino]acetyl]amino]-3-methoxyanilino]-5-chloropyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C28H34ClN7O5  1
1
IC50 = 20900 nM
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CP0482298
 Compound Info 
2-[3-[(4-tert-butylbenzoyl)amino]phenyl]-N-methyl-4-(4-morpholin-4-ylanilino)-1,3-thiazole-5-carboxamide
   Show/Hide
 C32H35N5O3S  1
1
IC50 = 8960 nM
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CP0489640
 Compound Info 
N-[3-[[2-[4-[[2-[bis(2-methoxyethyl)amino]acetyl]amino]anilino]-5-fluoropyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C27H32FN7O4  1
1
IC50 = 36900 nM
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CP0489641
 Compound Info 
N-[3-[[5-chloro-2-[4-(oxolan-2-ylmethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C24H24ClN5O3  1
1
IC50 = 19100 nM
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CP0493760
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-(pyridin-4-ylmethyl)carbamodithioate
   Show/Hide
 C28H26FN7O2S2  1
1
IC50 = 501 nM
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CP0498801
 Compound Info 
6-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-7-(naphthalen-1-ylmethyl)pteridine-2,4-dione
   Show/Hide
 C25H28N4O3S  1
1
EC50 = 151 nM
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CP0508234
 Compound Info 
2-[4-[[5-fluoro-4-[3-(propanoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-(pyridin-3-ylmethyl)carbamodithioate
   Show/Hide
 C28H28FN7O2S2  1
1
IC50 > 40000 nM
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CP0519597
 Compound Info 
N-[3-[[2-[4-[2-[bis(2-methoxyethyl)amino]-2-oxoethoxy]anilino]-5-chloropyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C27H31ClN6O5  1
1
IC50 = 20100 nM
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CP0519598
 Compound Info 
N-[3-[[2-[4-[[2-[bis(2-methoxyethyl)amino]acetyl]amino]anilino]-5-chloropyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C27H32ClN7O4  1
1
IC50 = 19900 nM
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CP0520079
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-propan-2-ylcarbamodithioate
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 C25H27FN6O2S2  1
1
IC50 = 9580 nM
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CP0520434
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-methyl-N-(pyridin-3-ylmethyl)carbamodithioate
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 C29H28FN7O2S2  1
1
IC50 = 4840 nM
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CP0530928
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl 3,4-dihydro-1H-isoquinoline-2-carbodithioate
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 C31H29FN6O2S2  1
1
IC50 > 40000 nM
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CP0530929
 Compound Info 
4-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]butyl 4-propan-2-ylpiperazine-1-carbodithioate
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 C31H38FN7O2S2  1
1
IC50 = 4450 nM
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CP0533231
 Compound Info 
4-[4-(morpholine-4-carbonyl)anilino]-2-[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]-1,3-thiazole-5-carboxamide
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 C29H24F3N5O4S  1
1
IC50 = 75310 nM
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CP0538215
 Compound Info 
2-[3-(furan-2-carbonylamino)phenyl]-4-[4-(4-methylpiperazin-1-yl)anilino]-1,3-thiazole-5-carboxamide
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 C26H26N6O3S  1
1
IC50 = 37390 nM
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CP0539270
 Compound Info 
N-[3-[[2-[3-methoxy-4-[(4-methylphenyl)sulfonylamino]anilino]-5-nitropyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C27H25N7O6S  1
1
IC50 = 34100 nM
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CP0540659
 Compound Info 
N-[3-[[5-chloro-2-[4-methoxy-3-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C27H31ClN6O4  1
1
IC50 = 3860 nM
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CP0547155
 Compound Info 
N-[3-[[2-[4-[[2-[bis(2-methoxyethyl)amino]acetyl]amino]-3-methylanilino]-5-chloropyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C28H34ClN7O4  1
1
IC50 = 35600 nM
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CP0553245
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl 4-phenylpiperazine-1-carbodithioate
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 C32H32FN7O2S2  1
1
IC50 = 15000 nM
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CP0553592
 Compound Info 
N-[3-[[5-chloro-2-[4-[3-(4-ethylpiperazin-1-yl)propoxy]-2-methylanilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C29H36ClN7O2  1
1
IC50 = 35260 nM
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CP0554434
 Compound Info 
methyl 2-[[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]amino]propanoate
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 C25H25ClN6O5  1
1
IC50 = 25200 nM
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CP0554868
 Compound Info 
4-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]butyl N,N-dimethylcarbamodithioate
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 C26H29FN6O2S2  1
1
IC50 = 10200 nM
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CP0555290
 Compound Info 
6-[(Z)-5-hydroxypent-1-enyl]-3-methyl-1-(2-methylpropyl)-7-(naphthalen-1-ylmethyl)pteridine-2,4-dione
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 C27H30N4O3  1
1
EC50 = 70 nM
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CP0559128
 Compound Info 
methyl 2-[[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]amino]acetate
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 C24H23ClN6O5  1
1
IC50 = 18000 nM
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CP0574425
 Compound Info 
N-[3-[[2-[4-[2-[bis(2-methoxyethyl)amino]-2-oxoethoxy]-3-chloroanilino]-5-chloropyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C27H30Cl2N6O5  1
1
IC50 = 19300 nM
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CP0574862
 Compound Info 
N-[3-[[2-[4-[bis(2-methoxyethyl)amino]anilino]-5-chloropyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C25H29ClN6O3  1
1
IC50 = 30500 nM
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CP0574863
 Compound Info 
N-[3-[[2-[4-[bis(2-methoxyethyl)amino]anilino]-5-fluoropyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C25H29FN6O3  1
1
IC50 = 23800 nM
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CP0575021
 Compound Info 
4-[5-ethylsulfonyl-2-(2- hydroxyethoxy)phenyl]-2-methyl-6-(1- methylpyrazol-4-yl)isoquinolin-1-one
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 C24H25N3O5S  1
1
IC50 = 880 nM
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CP0575086
 Compound Info 
2-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]ethyl N-[(3-fluorophenyl)methyl]carbamodithioate
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 C29H26F2N6O2S2  1
1
IC50 = 1150 nM
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CP0576080
 Compound Info 
2-[3-[(3-fluorobenzoyl)amino]phenyl]-4-[4-(4-methylpiperazin-1-yl)anilino]-1,3-thiazole-5-carboxylic acid
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 C28H26FN5O3S  1
1
IC50 = 35140 nM
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CP0689377
 Compound Info 
SPEBRUTINIB
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 C22H22FN5O3  1
1
IC50 = 29400 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone)
Cell Line Name Organism Disease
Cheptage
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HT-1080
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
2fTGH-U3A
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
HT1080-luc2
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
U2OS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SaOS-2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
G-292 clone A141B1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
HOS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
MG-63
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SJSA-1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CXCR4
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CCR5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
143.98.2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).X4/R5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
PathHunter U2OS DRD3 beta-arrestin
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SW1353
 Cell Line Info 
Homo sapiens (Human) Primary central chondrosarcoma
PC-3
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3M
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PPC-1
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
VCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MDA-PCa-2b
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
RMS13
 Cell Line Info 
Mus musculus (Mouse) Mouse rhabdomyosarcoma
UMR-106
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
ROS 17/2.8
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
MC3T3-E1
 Cell Line Info 
Mus musculus (Mouse) -