General Information of the Cell Line
Cell Line ID
CL000136
Cell Line Name
G-292 clone A141B1
Synonyms
G 292 Clone A 141B1
G-292, clone A141B1
G292CLONEA141B1
G-292
G292
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2909
Tissue Information
Bone
Disease
Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01092, Platelet-derived growth factor receptor alpha
Compound ID Compound Name Compound Formula
CP0445570
N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamoyl]-2-methylbenzamide
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C26H23N3O5
 2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 7.6 nM
   TI
   LI
   LO
   TS
CP0441747
phenyl N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamate
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C24H20N2O5
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0442494
2-chloro-N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamothioyl]benzamide
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C25H20ClN3O4S
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0382395
N-[[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]carbamoyl]-2-methylbenzamide
   Show/Hide
C25H22N4O5
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0441748
1-(2-cyclohexylethyl)-3-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]urea
   Show/Hide
C26H31N3O4
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0110944
1-cyclohexyl-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
   Show/Hide
C23H26N4O4
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0445571
N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamothioyl]benzamide
   Show/Hide
C25H21N3O4S
 1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
CP0378828
1-(2-cyclohexylethyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
   Show/Hide
C25H30N4O4
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0424722
1-cyclohexyl-3-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]urea
   Show/Hide
C24H27N3O4
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0441745
N-[[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamothioyl]cyclohexanecarboxamide
   Show/Hide
C25H27N3O4S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0494682
2-Cyclohexylethyl N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]-phenyl}carbamate
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C26H30N2O5
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0161826
1-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(2-phenylacetyl)thiourea
   Show/Hide
C26H23N3O4S
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0408905
1-(cyclohexylmethyl)-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]thiourea
   Show/Hide
C24H28N4O3S
 1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
CP0457028
1-cyclohexyl-3-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)thiourea
   Show/Hide
C24H27N3O3S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0435526
1-benzyl-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]thiourea
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C24H22N4O3S
 1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
CP0002778
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
C29H31N7O
 1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone)
Cell Line Name Organism Disease
Raji Homo sapiens (Human) EBV-related Burkitt lymphoma
Cheptage Homo sapiens (Human) EBV-related Burkitt lymphoma
HT-1080 Homo sapiens (Human) Fibrosarcoma
2fTGH-U3A Homo sapiens (Human) Fibrosarcoma
HT1080-luc2 Homo sapiens (Human) Fibrosarcoma
U2OS Homo sapiens (Human) Osteosarcoma
SaOS-2 Homo sapiens (Human) Osteosarcoma
HOS Homo sapiens (Human) Osteosarcoma
MG-63 Homo sapiens (Human) Osteosarcoma
SJSA-1 Homo sapiens (Human) Osteosarcoma
GHOST(3).CXCR4 Homo sapiens (Human) Osteosarcoma
GHOST(3).CCR5 Homo sapiens (Human) Osteosarcoma
143.98.2 Homo sapiens (Human) Osteosarcoma
GHOST(3).X4/R5 Homo sapiens (Human) Osteosarcoma
PathHunter U2OS DRD3 beta-arrestin Homo sapiens (Human) Osteosarcoma
SW1353 Homo sapiens (Human) Primary central chondrosarcoma
PC-3 Homo sapiens (Human) Prostate carcinoma
PC-3M Homo sapiens (Human) Prostate carcinoma
PC-3-AR Homo sapiens (Human) Prostate carcinoma
PPC-1 Homo sapiens (Human) Prostate carcinoma
VCaP Homo sapiens (Human) Prostate carcinoma
MDA-PCa-2b Homo sapiens (Human) Prostate carcinoma
RMS13 Mus musculus (Mouse) Mouse rhabdomyosarcoma
UMR-106 Rattus norvegicus (Rat) Rat osteosarcoma
ROS 17/2.8 Rattus norvegicus (Rat) Rat osteosarcoma
MC3T3-E1 Mus musculus (Mouse) -