General Information of the Cell Line
Cell Line ID
CL000700
Cell Line Name
VCaP
Synonyms
VCAP
Vcap
Vertebral Cancer of the Prostate
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2235
Tissue Information
Bone
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00897, Eag homolog
 Protein Info 
Compound ID Compound Name Compound Formula
CP0567397
 Compound Info 
sodium;5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenolate
   Show/Hide
C13H13N4NaO
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0961996
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol methanesulfonate
   Show/Hide
C14H18N4O4S
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0966203
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol hemioxalate
   Show/Hide
C15H16N4O5
  1
1
IC50 = 150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0954039
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol ethane-1,2-disulfonate
   Show/Hide
C15H20N4O7S2
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0969072
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol nitrate
   Show/Hide
C13H15N5O4
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0970228
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol benzenesulfonate
   Show/Hide
C19H20N4O4S
  1
1
IC50 = 210 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0956172
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol hemisuccinate
   Show/Hide
C17H20N4O5
  1
1
IC50 = 220 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0964077
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol hydrochloride
   Show/Hide
C13H15ClN4O
  1
1
IC50 = 220 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576217
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol
   Show/Hide
C13H14N4O
  1
1
IC50 = 230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0961173
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol hydrobromide
   Show/Hide
C13H15BrN4O
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0961995
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol 4-methylbenzenesulfonate
   Show/Hide
C20H22N4O4S
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0964593
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol 2,5-dihydroxybenzoate
   Show/Hide
C20H20N4O5
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0946318
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol sulfate
   Show/Hide
C13H16N4O5S
  1
1
IC50 = 260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0967514
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol maleate
   Show/Hide
C17H18N4O5
  1
1
IC50 = 260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537350
 Compound Info 
1-(1,3-thiazol-2-yldiazenyl)naphthalen-2-ol
   Show/Hide
C13H9N3OS
  1
1
IC50 = 310 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569841
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol;naphthalene-1,5-disulfonic acid
   Show/Hide
C23H22N4O7S2
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0955626
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol dinaphthalene-2-sulfonate
   Show/Hide
C23H22N4O4S
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0957115
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol fumarate
   Show/Hide
C17H18N4O5
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0961994
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol 2-hydroxyacetate
   Show/Hide
C15H18N4O4
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0964692
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol ethanesulfonate
   Show/Hide
C15H20N4O4S
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0964898
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol 2-hydroxysuccinate
   Show/Hide
C17H20N4O6
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0965927
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol(2R,3R)-2,3-dihydroxysuccinate
   Show/Hide
C17H20N4O7
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0969073
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol 2-oxopropanoate
   Show/Hide
C16H18N4O4
  1
1
IC50 > 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01157, Serine/threonine-protein kinase RIO2
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0037412
 Compound Info 
(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorobenzene)sulfonyl]-2-hydroxy-2-methylpropanamide
   Show/Hide
 C18H14F4N2O4S  2
1
IC50 = 51600 nM
   TI
   LI
   LO
   TS
2
IC50 = 51607 nM
   TI
   LI
   LO
   TS
CP0217093
 Compound Info 
Enobosarm
   Show/Hide
 C19H14F3N3O3  1
1
IC50 = 24470 nM
   TI
   LI
   LO
   TS
CP0410892
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[2-(trifluoromethyl)phenyl]sulfonylpropanamide
   Show/Hide
 C18H14F6N2O6S  1
1
IC50 = 27550 nM
   TI
   LI
   LO
   TS
CP0482916
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[2-(trifluoromethyl)phenoxy]propanamide
   Show/Hide
 C18H14F6N2O5  1
1
IC50 = 27160 nM
   TI
   LI
   LO
   TS
CP0482950
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethoxy)phenoxy]propanamide
   Show/Hide
 C18H14F6N2O6  1
1
IC50 = 9600 nM
   TI
   LI
   LO
   TS
CP0543070
 Compound Info 
3-[4-cyano-2-(trifluoromethyl)phenoxy]-N-[4-cyano-2-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
   Show/Hide
 C20H13F6N3O3  1
1
IC50 = 17700 nM
   TI
   LI
   LO
   TS
CP0549132
 Compound Info 
3-chloro-5-[8-oxo-5-(4-piperidin-4-yloxyphenyl)-6-sulfanylidene-5,7-diazaspiro[3.4]octan-7-yl]pyridine-2-carbonitrile
   Show/Hide
 C23H22ClN5O2S  1
1
IC50 = 503 nM
   TI
   LI
   LO
   TS
CP0567476
 Compound Info 
5-[8-oxo-5-(4-piperidin-4-yloxyphenyl)-6-sulfanylidene-5,7-diazaspiro[3.4]octan-7-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
   Show/Hide
 C24H22F3N5O2S  1
1
IC50 = 306 nM
   TI
   LI
   LO
   TS
CP0569841
 Compound Info 
5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol;naphthalene-1,5-disulfonic acid
   Show/Hide
 C23H22N4O7S2  1
1
IC50 > 500 nM
   TI
   LI
   LO
   TS
CP0964692
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol ethanesulfonate
   Show/Hide
 C15H20N4O4S  1
1
IC50 > 500 nM
   TI
   LI
   LO
   TS
CP0969073
 Compound Info 
(E)-5-(dimethylamino)-2-(pyridin-2-yldiazenyl)phenol 2-oxopropanoate
   Show/Hide
 C16H18N4O4  1
1
IC50 > 500 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone)
Cell Line Name Organism Disease
Raji
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
Cheptage
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HT-1080
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
2fTGH-U3A
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
HT1080-luc2
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
U2OS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SaOS-2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
G-292 clone A141B1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
HOS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
MG-63
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SJSA-1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CXCR4
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CCR5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
143.98.2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).X4/R5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
PathHunter U2OS DRD3 beta-arrestin
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SW1353
 Cell Line Info 
Homo sapiens (Human) Primary central chondrosarcoma
PC-3
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3M
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PPC-1
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MDA-PCa-2b
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
RMS13
 Cell Line Info 
Mus musculus (Mouse) Mouse rhabdomyosarcoma
UMR-106
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
ROS 17/2.8
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
MC3T3-E1
 Cell Line Info 
Mus musculus (Mouse) -