General Information of the Cell Line
Cell Line ID
CL000197
Cell Line Name
MG-63
Synonyms
M-G63
MG63
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0426
Tissue Information
Bone
Disease
Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01679, 17-beta-hydroxysteroid dehydrogenase type 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0352160
 Compound Info 
(4R,5R)-4-(2-fluorophenyl)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-yl)methyl)-1-methylpyrrolidin-2-one
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C21H19FN2O2S
  1
1
IC50 = 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0308226
 Compound Info 
(4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-1-methylpyrrolidin-2-one
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C22H19F2NO2S
  1
1
IC50 = 60 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0075405
 Compound Info 
(4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-yl)methyl)-1-methyl-4-phenylpyrrolidin-2-one
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C21H20N2O2S
  1
1
IC50 = 90 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0531972
 Compound Info 
(4R,5R)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-1-methyl-4-phenylpyrrolidin-2-one
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C22H20FNO2S
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0221602
 Compound Info 
(4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-2-yl)methyl)-1-methyl-4-phenylpyrrolidin-2-one
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C22H21NO4S2
  1
1
IC50 = 480 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
 Protein Info 
Protein ID: PT01092, Platelet-derived growth factor receptor alpha
 Protein Info 
Protein ID: PT00844, Platelet-derived growth factor receptor beta
 Protein Info 
Protein ID: PT02513, Steroid hormone receptor ERR1
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone)
Cell Line Name Organism Disease
Raji
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
Cheptage
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HT-1080
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
2fTGH-U3A
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
HT1080-luc2
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
U2OS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SaOS-2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
G-292 clone A141B1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
HOS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SJSA-1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CXCR4
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CCR5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
143.98.2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).X4/R5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
PathHunter U2OS DRD3 beta-arrestin
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SW1353
 Cell Line Info 
Homo sapiens (Human) Primary central chondrosarcoma
PC-3
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3M
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PPC-1
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
VCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MDA-PCa-2b
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
RMS13
 Cell Line Info 
Mus musculus (Mouse) Mouse rhabdomyosarcoma
UMR-106
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
ROS 17/2.8
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
MC3T3-E1
 Cell Line Info 
Mus musculus (Mouse) -