General Information of the Cell Line
Cell Line ID
CL000807
Cell Line Name
MDA-PCa-2b
Synonyms
MDA PCa 2b
MDAPCa-2b
MDAPCa2b
MDAPCA2B
MDAPC2B
MDA2B
M.D. Anderson-Prostate Cancer-2b
Category
Cancer cell line
Organism
Homo sapiens (Human)
Tissue Information
Bone
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00894, Androgen receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0862669
 Compound Info 
(2R,6S)-4-(3-Trifluoromethyl-phenyl)-4-aza-tricyclo[5.2.2.0*2,6*]undec-8-ene-3,5-dione
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C17H14F3NO2
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0860626
 Compound Info 
(2S,6R)-4-(3,4-Dimethyl-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C17H17NO2
  1
1
IC50 = 96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0855754
 Compound Info 
(2S,6R)-4-(3-Chloro-4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
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C15H11ClFNO2
  1
1
IC50 = 132 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0848003
 Compound Info 
(2R,6S,8S,10R)-4-[3-(trifluoromethyl)phenyl]-4-azatetracyclo[5.3.2.0^{2,6}.0^{8,10}]dodec-11-ene-3,5-dione
   Show/Hide
C18H14F3NO2
  1
1
IC50 = 148 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0880496
 Compound Info 
(2S,6R)-4-(3-Trifluoromethyl-phenyl)-4-aza-tricyclo[5.3.2.0*2,6*]dodecane-3,5-dione
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C18H18F3NO2
  1
1
IC50 = 179 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0883915
 Compound Info 
(2R,6S)-4-(4-nitrophenyl)-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione
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C15H12N2O4
  1
1
IC50 = 179 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0917601
 Compound Info 
(2R,6S)-4-(3,4-Dichloro-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C15H11Cl2NO2
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0855770
 Compound Info 
(2S,6R)-4-(3,5-Dichloro-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
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C15H11Cl2NO2
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0870105
 Compound Info 
(2S,6R)-4-(3,5-Bis-trifluoromethyl-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C17H11F6NO2
  1
1
IC50 = 198 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0845025
 Compound Info 
(2S,6R)-4-(3-Trifluoromethyl-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
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C16H14F3NO2
  1
1
IC50 = 205 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0855510
 Compound Info 
(2S,6R)-4-Quinolin-7-yl-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C18H14N2O2
  1
1
IC50 = 234 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0855812
 Compound Info 
(2S,6R)-4-Naphthalen-2-yl-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C19H15NO2
  1
1
IC50 = 265 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0897800
 Compound Info 
(2S,6R)-4-Naphthalen-2-yl-4-aza-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
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C19H17NO2
  1
1
IC50 = 265 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0897803
 Compound Info 
(2S,6R)-4-(3-Trifluoromethyl-phenyl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C16H12F3NO2
  1
1
IC50 = 410 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0146696
 Compound Info 
Bicalutamide
   Show/Hide
C18H14F4N2O4S
  1
1
IC50 = 725 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0855813
 Compound Info 
(2S,6R)-4-(8-Hydroxy-quinolin-5-yl)-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione
   Show/Hide
C18H14N2O3
  1
1
IC50 = 3639 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0876327
 Compound Info 
(2R,6R)-8-Methyl-4-(4-nitro-naphthalen-1-yl)-4,8-diaza-tricyclo[5.2.2.0*2,6*]undec-10-ene-3,5,9-trione
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C20H15N3O5
  1
1
IC50 = 8460 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone)
Cell Line Name Organism Disease
Raji
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
Cheptage
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HT-1080
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
2fTGH-U3A
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
HT1080-luc2
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
U2OS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SaOS-2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
G-292 clone A141B1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
HOS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
MG-63
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SJSA-1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CXCR4
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CCR5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
143.98.2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).X4/R5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
PathHunter U2OS DRD3 beta-arrestin
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SW1353
 Cell Line Info 
Homo sapiens (Human) Primary central chondrosarcoma
PC-3
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3M
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PPC-1
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
VCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
RMS13
 Cell Line Info 
Mus musculus (Mouse) Mouse rhabdomyosarcoma
UMR-106
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
ROS 17/2.8
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
MC3T3-E1
 Cell Line Info 
Mus musculus (Mouse) -