General Information of the Cell Line
Cell Line ID
CL000285
Cell Line Name
PC-3M
Synonyms
PC3-M
PC-3/M
PC3M
Pc3M
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_9555
Tissue Information
Bone
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00962, Glycogen synthase kinase-3 beta
 Protein Info 
Compound ID Compound Name Compound Formula
CP0158762
 Compound Info 
[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
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C18H20ClN5
  1
1
IC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436413
 Compound Info 
4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine
   Show/Hide
C17H18ClN5
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0347605
 Compound Info 
[4-(4-chlorophenyl)-1-(7H-purin-6-yl)piperidin-4-yl]methanamine
   Show/Hide
C17H19ClN6
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436554
 Compound Info 
[4-[(4-chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
   Show/Hide
C19H22ClN5
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511843
 Compound Info 
[4-(4-chlorophenyl)-1-(1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-4-yl]methanamine
   Show/Hide
C19H21ClN4
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0157904
 Compound Info 
[4-[(4-chlorophenyl)methyl]-1-(7H-purin-6-yl)piperidin-4-yl]methanamine
   Show/Hide
C18H21ClN6
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0203673
 Compound Info 
(4-chlorophenyl)-[1-(1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-4-yl]methanamine
   Show/Hide
C19H21ClN4
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0025139
 Compound Info 
4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-
   Show/Hide
C18H20ClN5
  1
1
IC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0215630
 Compound Info 
(4-chlorophenyl)-[1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
   Show/Hide
C18H20ClN5
  1
1
IC50 = 7500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0311537
 Compound Info 
[1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
   Show/Hide
C12H17N5
  1
1
IC50 = 11000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016702
 Compound Info 
N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide
   Show/Hide
C20H20BrN3O2S
  1
1
IC50 = 15000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0347600
 Compound Info 
1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine
   Show/Hide
C11H15N5
  1
1
IC50 = 15000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0158765
 Compound Info 
phenyl-[1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
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C18H21N5
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0315718
 Compound Info 
[1-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
   Show/Hide
C11H16N6
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0357891
 Compound Info 
1-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidin-4-amine
   Show/Hide
C10H14N6
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00845, RAC-alpha serine/threonine-protein kinase
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Bone)
Cell Line Name Organism Disease
Raji
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
Cheptage
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HT-1080
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
2fTGH-U3A
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
HT1080-luc2
 Cell Line Info 
Homo sapiens (Human) Fibrosarcoma
U2OS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SaOS-2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
G-292 clone A141B1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
HOS
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
MG-63
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SJSA-1
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CXCR4
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).CCR5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
143.98.2
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
GHOST(3).X4/R5
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
PathHunter U2OS DRD3 beta-arrestin
 Cell Line Info 
Homo sapiens (Human) Osteosarcoma
SW1353
 Cell Line Info 
Homo sapiens (Human) Primary central chondrosarcoma
PC-3
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PC-3-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
PPC-1
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
VCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MDA-PCa-2b
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
RMS13
 Cell Line Info 
Mus musculus (Mouse) Mouse rhabdomyosarcoma
UMR-106
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
ROS 17/2.8
 Cell Line Info 
Rattus norvegicus (Rat) Rat osteosarcoma
MC3T3-E1
 Cell Line Info 
Mus musculus (Mouse) -