General Information of the Compound
| Compound ID |
CP0110944
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
1-cyclohexyl-3-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]urea
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C23H26N4O4
|
||||||||||||||||||
| Molecular Weight |
422.485
|
||||||||||||||||||
| Canonical SMILES |
COc1cc2ncnc(Oc3ccc(NC(=O)NC4CCCCC4)cc3)c2cc1OC
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C23H26N4O4/c1-29-20-12-18-19(13-21(20)30-2)24-14-25-22(18)31-17-10-8-16(9-11-17)27-23(28)26-15-6-4-3-5-7-15/h8-15H,3-7H2,1-2H3,(H2,26,27,28)
Show/Hide
|
||||||||||||||||||
| InChIKey |
ROYLPDZGPLFQSV-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00922, Epidermal growth factor receptor
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT01092, Platelet-derived growth factor receptor alpha