General Information of the Cell Line
Cell Line ID
CL000052
Cell Line Name
A-431
Synonyms
A431
A431/P
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0037
Tissue Information
Skin
Disease
Skin squamous cell carcinoma (NCIt: C4819)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02392, B2 bradykinin receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0847066
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
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C31H29Cl3N4O4
  1
1
IC50 = 1.3 nM
 Bioactivity Info 
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CP0943579
 Compound Info 
4-{(E)-2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide hydrochloride
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C30H29BrCl3N5O4
  1
1
IC50 = 1.4 nM
 Bioactivity Info 
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CP0885378
 Compound Info 
4-{(E)-2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
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C29H27BrCl3N5O4
  1
1
IC50 = 1.5 nM
 Bioactivity Info 
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CP0945053
 Compound Info 
(E)-3-(4-Acetylamino-phenyl)-N-({[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide hydrochloride
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C29H27BrCl3N5O4
  1
1
IC50 = 1.6 nM
 Bioactivity Info 
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CP0887793
 Compound Info 
3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide; Dihydrochloride
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C28H27BrCl4N6O4
  1
1
IC50 = 2.4 nM
 Bioactivity Info 
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CP0885577
 Compound Info 
(E)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(3-methyl-ureido)-phenyl]-acrylamide hydrochloride
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C29H28BrCl3N6O4
  1
1
IC50 = 2.6 nM
 Bioactivity Info 
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CP0885377
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
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C30H28Cl3N5O4
  1
1
IC50 = 3.1 nM
 Bioactivity Info 
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CP0404246
 Compound Info 
Firazyr
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C59H89N19O13S
  1
1
IC50 = 3.3 nM
 Bioactivity Info 
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CP0885966
 Compound Info 
5-{2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid dimethylamide; Dihydrochloride
   Show/Hide
C29H29BrCl4N6O4
  1
1
IC50 = 3.7 nM
 Bioactivity Info 
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CP0902615
 Compound Info 
(E)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide hydrochloride
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C31H29BrCl3N5O4
  1
1
IC50 = 4.1 nM
 Bioactivity Info 
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CP0902447
 Compound Info 
(E)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-(4-methanesulfonylamino-phenyl)-acrylamide hydrochloride
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C28H27BrCl3N5O5S
  1
1
IC50 = 4.8 nM
 Bioactivity Info 
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CP0885937
 Compound Info 
5-{2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide; Dihydrochloride
   Show/Hide
C28H27BrCl4N6O4
  1
1
IC50 = 9.1 nM
 Bioactivity Info 
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CP0457306
 Compound Info 
3-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide
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C32H30Cl2N4O4
  1
1
IC50 = 14 nM
 Bioactivity Info 
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CP0943624
 Compound Info 
(E)-3-[4-(Acetyl-methyl-amino)-phenyl]-N-({[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide hydrochloride
   Show/Hide
C30H29BrCl3N5O4
  1
1
IC50 = 16 nM
 Bioactivity Info 
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CP0882976
 Compound Info 
3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N-(2-methoxy-ethyl)-benzamide hydrochloride
   Show/Hide
C29H30BrCl3N6O5
  1
1
IC50 = 20 nM
 Bioactivity Info 
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CP0920265
 Compound Info 
3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N,N-dimethyl-benzamide hydrochloride
   Show/Hide
C28H28BrCl3N6O4
  1
1
IC50 = 20 nM
 Bioactivity Info 
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CP0392560
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(1,2-dimethyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
   Show/Hide
C30H29Cl2N5O4
  1
1
IC50 = 43 nM
 Bioactivity Info 
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CP0465050
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinazolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
   Show/Hide
C30H27Cl2N5O4
  1
1
IC50 = 59 nM
 Bioactivity Info 
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CP0902432
 Compound Info 
2-[3-(3-Acetyl-phenyl)-ureido]-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide hydrochloride
   Show/Hide
C27H25BrCl3N5O4
  1
1
IC50 = 61 nM
 Bioactivity Info 
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CP0395223
 Compound Info 
N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-2-[[3-[(2-methoxyacetyl)amino]phenyl]carbamoylamino]-N-methylacetamide
   Show/Hide
C28H27BrCl2N6O5
  1
1
IC50 = 75 nM
 Bioactivity Info 
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CP0897038
 Compound Info 
(Z)-N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-3-phenyl-acrylamide hydrochloride
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C27H24BrCl3N4O3
  1
1
IC50 = 120 nM
 Bioactivity Info 
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CP0946107
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-m-tolyl-ureido)-acetamide hydrochloride
   Show/Hide
C26H25BrCl3N5O3
  1
1
IC50 = 140 nM
 Bioactivity Info 
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CP0470615
 Compound Info 
N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-N-methyl-2-[(2-methylphenyl)carbamoylamino]acetamide
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C26H24BrCl2N5O3
  1
1
IC50 = 150 nM
 Bioactivity Info 
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CP0523171
 Compound Info 
3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-benzoic acid ethyl ester
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C28H26BrCl2N5O5
  1
1
IC50 = 150 nM
 Bioactivity Info 
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CP0902621
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-phenyl-ureido)-acetamide hydrochloride
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C25H23BrCl3N5O3
  1
1
IC50 = 150 nM
 Bioactivity Info 
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CP0856319
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-[3-(3-nitro-phenyl)-ureido]-acetamide hydrochloride
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C25H22BrCl3N6O5
  1
1
IC50 = 180 nM
 Bioactivity Info 
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CP0895135
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-cyano-phenyl)-ureido]-N-methyl-acetamide hydrochloride
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C26H22BrCl3N6O3
  1
1
IC50 = 190 nM
 Bioactivity Info 
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CP0861119
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-methoxy-phenyl)-ureido]-N-methyl-acetamide hydrochloride
   Show/Hide
C26H25BrCl3N5O4
  1
1
IC50 = 200 nM
 Bioactivity Info 
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CP0463789
 Compound Info 
N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]hexanamide
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C24H27BrCl2N4O3
  1
1
IC50 = 240 nM
 Bioactivity Info 
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CP0885625
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-2-(3-p-tolyl-ureido)-acetamide hydrochloride
   Show/Hide
C26H25BrCl3N5O3
  1
1
IC50 = 260 nM
 Bioactivity Info 
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CP0535264
 Compound Info 
N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]-3-phenylpropanamide
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C27H25BrCl2N4O3
  1
1
IC50 = 350 nM
 Bioactivity Info 
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CP0445309
 Compound Info 
N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]-4-phenylbutanamide
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C28H27BrCl2N4O3
  1
1
IC50 = 480 nM
 Bioactivity Info 
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CP0374222
 Compound Info 
N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-N-methyl-2-[(2-phenoxyacetyl)amino]acetamide
   Show/Hide
C26H23BrCl2N4O4
  1
1
IC50 = 510 nM
 Bioactivity Info 
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CP0410477
 Compound Info 
2-(3-Benzoyl-ureido)-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide
   Show/Hide
C26H22BrCl2N5O4
  1
1
IC50 = 510 nM
 Bioactivity Info 
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CP0885968
 Compound Info 
2-(3-Benzyl-ureido)-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide hydrochloride
   Show/Hide
C26H25BrCl3N5O3
  1
1
IC50 = 570 nM
 Bioactivity Info 
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CP0454516
 Compound Info 
N-[2-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichloro-N-methylanilino]-2-oxoethyl]butanamide
   Show/Hide
C22H23BrCl2N4O3
  1
1
IC50 = 610 nM
 Bioactivity Info 
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CP0885535
 Compound Info 
N-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-2-phenyl-acetamide hydrochloride
   Show/Hide
C26H24BrCl3N4O3
  1
1
IC50 = 670 nM
 Bioactivity Info 
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CP0429345
 Compound Info 
N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-2-[[2-(dimethylamino)acetyl]amino]-N-methylacetamide
   Show/Hide
C22H24BrCl2N5O3
  1
1
IC50 = 830 nM
 Bioactivity Info 
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CP0494786
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-benzooxazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
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C29H26Cl2N4O5
  1
1
IC50 = 860 nM
 Bioactivity Info 
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CP0891122
 Compound Info 
N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-chloro-phenyl)-ureido]-N-methyl-acetamide hydrochloride
   Show/Hide
C25H22BrCl4N5O3
  1
1
IC50 = 1900 nM
 Bioactivity Info 
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CP0511366
 Compound Info 
N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4-dichlorophenyl]-2-(ethylcarbamoylamino)-N-methylacetamide
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C21H22BrCl2N5O3
  1
1
IC50 = 3000 nM
 Bioactivity Info 
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CP0511276
 Compound Info 
4-((E)-2-{[({2,4-Dichloro-3-[2-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide
   Show/Hide
C32H31Cl2N5O4
  1
1
IC50 = 3500 nM
 Bioactivity Info 
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CP0920729
 Compound Info 
2-Acetylamino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide hydrochloride
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C20H20BrCl3N4O3
  1
1
IC50 = 4100 nM
 Bioactivity Info 
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CP0383199
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
   Show/Hide
C30H27Cl2N5O4
  1
1
IC50 = 4300 nM
 Bioactivity Info 
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CP0410512
 Compound Info 
3-[3-({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-ureido]-benzoic acid
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C26H22BrCl2N5O5
  1
1
IC50 = 5200 nM
 Bioactivity Info 
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CP0377942
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(6-methyl-pyridin-2-ylmethoxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
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C28H28Cl2N4O4
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0410682
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(3-methyl-isoquinolin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
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C31H28Cl2N4O4
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0521181
 Compound Info 
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-7-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
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C31H28Cl2N4O4
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0394067
 Compound Info 
2-[3-(3-Amino-phenyl)-ureido]-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-N-methyl-acetamide
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C25H23BrCl2N6O3
  1
1
IC50 > 1000 nM
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Protein ID: PT01494, Beta-2 adrenergic receptor
 Protein Info 
Protein ID: PT00958, Cholecystokinin receptor type A
 Protein Info 
Protein ID: PT01235, Cyclin-dependent kinase 9
 Protein Info 
Protein ID: PT00922, Epidermal growth factor receptor
 Protein Info 
Protein ID: PT01124, Gastrin/cholecystokinin type B receptor
 Protein Info 
Protein ID: PT04657, Glucose transporter type 1
 Protein Info 
Protein ID: PT01557, Indoleamine 2,3-dioxygenase 1
 Protein Info 
Protein ID: PT01104, Insulin-like growth factor 1 receptor
 Protein Info 
Protein ID: PT00844, Platelet-derived growth factor receptor beta
 Protein Info 
Protein ID: PT01587, Stearoyl-CoA desaturase
 Protein Info 
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
   Show/Hide
 C14H20N2O3  1
1
IC50 = 4200 nM
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CP0007142
 Compound Info 
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
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 C29H26ClFN4O4S  2
1
IC50 = 3590 nM
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2
IC50 = 4800 nM
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CP0011998
 Compound Info 
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
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 C16H14BrN3O2  1
1
IC50 = 12600 nM
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CP0033646
 Compound Info 
AZD-9291
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 C28H33N7O2  1
1
IC50 = 615.6 nM
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CP0036082
 Compound Info 
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
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 C22H24ClFN4O3  1
1
IC50 = 3300 nM
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CP0039635
 Compound Info 
2,4-diaminofuro[2,3-d]pyrimidine, 13
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 C19H24N4O2  1
1
IC50 = 106300 nM
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CP0047127
 Compound Info 
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
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 C13H8Cl2N2O4  1
1
IC50 = 8800 nM
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CP0065286
 Compound Info 
AVL-301
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 C27H28F3N7O3  2
1
GI50 = 547 nM
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2
IC50 = 1794 nM
   TI
   LI
   LO
   TS
CP0091116
 Compound Info 
2-benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine
   Show/Hide
 C19H16BrN5  1
1
IC50 = 31800 nM
   TI
   LI
   LO
   TS
CP0091317
 Compound Info 
US9422297, AAG145-131
   Show/Hide
 C17H13BrN4  1
1
IC50 > 500000 nM
   TI
   LI
   LO
   TS
CP0093434
 Compound Info 
US9422297, AAG145-158
   Show/Hide
 C17H14N4  1
1
IC50 = 4900 nM
   TI
   LI
   LO
   TS
CP0093436
 Compound Info 
US9422297, AAG145-164
   Show/Hide
 C17H12ClFN4  1
1
IC50 = 158100 nM
   TI
   LI
   LO
   TS
CP0096083
 Compound Info 
4-N-(3-bromophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C21H20BrN5O2  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0111386
 Compound Info 
5-naphthalen-1-ylsulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
 C20H15N5S  1
1
IC50 > 200000 nM
   TI
   LI
   LO
   TS
CP0118530
 Compound Info 
5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxythiophene-2-carboxamide
   Show/Hide
 C26H18ClFN4O3S  1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0118633
 Compound Info 
N-(2-aminophenyl)-5-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]thiophene-2-carboxamide
   Show/Hide
 C32H23ClFN5O2S  1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0118656
 Compound Info 
(E)-3-(4-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)-N-hydroxyacrylamide
   Show/Hide
 C30H22ClFN4O3  1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS
CP0118658
 Compound Info 
5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxyfuran-2-carboxamide
   Show/Hide
 C26H18ClFN4O4  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CP0126790
 Compound Info 
4-N-(3-bromophenyl)-6-(naphthalen-1-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C23H18BrN5  1
1
IC50 > 200000 nM
   TI
   LI
   LO
   TS
CP0146673
 Compound Info 
3-(1-acetyl-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one
   Show/Hide
 C20H16N2O3  1
1
IC50 = 155674.5697 nM
   TI
   LI
   LO
   TS
CP0146674
 Compound Info 
3-(1-acetyl-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)-5-bromo-2H-chromen-2-one
   Show/Hide
 C20H15BrN2O4  1
1
IC50 = 159976.5945 nM
   TI
   LI
   LO
   TS
CP0151685
 Compound Info 
N-(2-aminophenyl)-4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]anilino]methyl]benzamide
   Show/Hide
 C30H27N7O  1
1
IC50 = 5011.87 nM
   TI
   LI
   LO
   TS
CP0167045
 Compound Info 
3-(1-acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one
   Show/Hide
 C21H18N2O4  1
1
IC50 = 189685.1458 nM
   TI
   LI
   LO
   TS
CP0167979
 Compound Info 
4-N-(3-bromophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C20H18BrN5  1
1
IC50 = 1210 nM
   TI
   LI
   LO
   TS
CP0173297
 Compound Info 
3-[3-(benzofuran-2-carbonyl)phenyl]-N-hydroxyacrylamide
   Show/Hide
 C18H13NO4  1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CP0193029
 Compound Info 
N-[2-phenyl-4-(1H-pyrazol-5-ylamino)quinazolin-7-yl]prop-2-enamide
   Show/Hide
 C20H16N6O  1
1
GI50 = 700 nM
   TI
   LI
   LO
   TS
CP0203178
 Compound Info 
N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
   Show/Hide
 C29H31N7O3  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0204538
 Compound Info 
N-[3-[[2-[2-methoxy-4-(4-morpholin-4-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
   Show/Hide
 C30H36N8O4  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0204863
 Compound Info 
(E)-N-hydroxy-3-(4-((4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenylamino)methyl)phenyl)acrylamide
   Show/Hide
 C26H24N6O2  2
1
IC50 = 3160 nM
   TI
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   TS
2
IC50 = 3162.28 nM
   TI
   LI
   LO
   TS
CP0232442
 Compound Info 
(E)-3-(5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)thiophen-2-yl)-N-hydroxyacrylamide
   Show/Hide
 C28H20ClFN4O3S  1
1
IC50 = 730 nM
   TI
   LI
   LO
   TS
CP0238377
 Compound Info 
5-(2,5-dimethoxyphenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
 C18H17N5O2S  1
1
IC50 = 38400 nM
   TI
   LI
   LO
   TS
CP0244796
 Compound Info 
2,4-diaminofuro[2,3-d]pyrimidine, 1b
   Show/Hide
 C16H16N4O2  1
1
IC50 > 250000 nM
   TI
   LI
   LO
   TS
CP0283354
 Compound Info 
N-(2-aminophenyl)-3-[4-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]phenyl]propanamide
   Show/Hide
 C36H29ClFN5O2  1
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
CP0303641
 Compound Info 
2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine
   Show/Hide
 C16H14ClN3O  1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS
CP0342425
 Compound Info 
3-(1-acetyl-5-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one
   Show/Hide
 C20H14Cl2N2O3  1
1
IC50 = 171314.6417 nM
   TI
   LI
   LO
   TS
CP0369877
 Compound Info 
3-(1-acetyl-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)-5-bromo-2H-chromen-2-one
   Show/Hide
 C20H15BrN2O3  1
1
IC50 = 117009.1185 nM
   TI
   LI
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   TS
CP0371872
 Compound Info 
2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimethoxybenzyl)-pyrrolo[2,3-d]pyrimidine
   Show/Hide
 C22H22BrN5O2  1
1
IC50 = 197400 nM
   TI
   LI
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   TS
CP0374755
 Compound Info 
N-[3-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
   Show/Hide
 C29H33N7O3  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0379500
 Compound Info 
N-(3,4-dimethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H19N3O3  1
1
IC50 = 9.7 nM
   TI
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   TS
CP0380834
 Compound Info 
N-(4-chlorophenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C14H12ClN3O  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
IC50 = 20.8 nM
   TI
   LI
   LO
   TS
CP0383277
 Compound Info 
2,6-dimethyl-N-naphthalen-1-ylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C18H15N3O  1
1
IC50 = 49.1 nM
   TI
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   LO
   TS
CP0383413
 Compound Info 
N-[2-methyl-5-(2-oxo-9-pyrazol-1-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]prop-2-enamide
   Show/Hide
 C25H19N5O2  1
1
GI50 = 5100 nM
   TI
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   LO
   TS
CP0383415
 Compound Info 
N-[2-methyl-5-(2-oxo-9-pyrazol-1-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]propanamide
   Show/Hide
 C25H21N5O2  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CP0388586
 Compound Info 
N-(2,4-dimethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H19N3O3  1
1
IC50 = 17.1 nM
   TI
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   TS
CP0391385
 Compound Info 
4-N-(4-chlorophenyl)-6-(naphthalen-1-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C23H18ClN5  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0391848
 Compound Info 
5-chloro-4-N-(3-fluorophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
 C16H11ClFN5  1
1
IC50 = 184100 nM
   TI
   LI
   LO
   TS
CP0395235
 Compound Info 
4-N-(4-chlorophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C21H20ClN5O2  1
1
IC50 = 5800 nM
   TI
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   TS
CP0398717
 Compound Info 
N-(1,3-benzodioxol-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H15N3O3  1
1
IC50 = 48.9 nM
   TI
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   TS
CP0400032
 Compound Info 
4-N-(4-chloro-2-fluorophenyl)-6-[(2,4-dichlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C19H13Cl3FN5  1
1
IC50 = 4900 nM
   TI
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   LO
   TS
CP0402191
 Compound Info 
4-N-(3-bromophenyl)-7-(naphthalen-1-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C23H18BrN5  1
1
IC50 = 36300 nM
   TI
   LI
   LO
   TS
CP0402192
 Compound Info 
4-N-(3-bromophenyl)-7-[(4-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C19H15BrClN5  1
1
IC50 = 16100 nM
   TI
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   LO
   TS
CP0402193
 Compound Info 
4-N-(3-bromophenyl)-7-[(3,4,5-trimethoxyphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C22H22BrN5O3  1
1
IC50 = 39000 nM
   TI
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   TS
CP0402194
 Compound Info 
4-N-(3-bromophenyl)-7-[(2-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C19H15BrClN5  1
1
IC50 = 88400 nM
   TI
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   TS
CP0411319
 Compound Info 
N-[3-[[2-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
   Show/Hide
 C27H31N7O3  1
1
IC50 > 10000 nM
   TI
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   TS
CP0415601
 Compound Info 
1-N,4-N-dimethyl-4-N-(5-methylfuro[2,3-d]pyrimidin-4-yl)benzene-1,4-diamine
   Show/Hide
 C15H16N4O  1
1
IC50 = 2.9 nM
   TI
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CP0416674
 Compound Info 
N'-hydroxy-N-[4-hydroxy-3-(phenylcarbamoyl)phenyl]heptanediamide
   Show/Hide
 C20H23N3O5  1
1
IC50 = 5850 nM
   TI
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   TS
CP0416676
 Compound Info 
N'-hydroxy-N-[4-hydroxy-3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]heptanediamide
   Show/Hide
 C21H22F3N3O5  1
1
IC50 = 2750 nM
   TI
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   TS
CP0416811
 Compound Info 
N-[3-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
   Show/Hide
 C27H27ClFN3O6  1
1
IC50 = 2600 nM
   TI
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   TS
CP0416813
 Compound Info 
N-(3-ethynylphenyl)-2-hydroxy-5-[7-(hydroxyamino)-7-oxoheptoxy]benzamide
   Show/Hide
 C22H24N2O5  1
1
IC50 = 1880 nM
   TI
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CP0417587
 Compound Info 
4-N-(3-ethynylphenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C21H18N6  1
1
IC50 = 900 nM
   TI
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   TS
CP0417588
 Compound Info 
4-N-(3-bromo-4-fluorophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C19H16BrFN6  1
1
IC50 = 12200 nM
   TI
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   TS
CP0418650
 Compound Info 
N,2,6-trimethyl-N-(3,4,5-trimethoxyphenyl)furo[2,3-d]pyrimidin-4-amine
   Show/Hide
 C18H21N3O4  1
1
IC50 > 300 nM
   TI
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   TS
CP0418813
 Compound Info 
4-N-(3-bromophenyl)-7-(naphthalen-2-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C23H18BrN5  1
1
IC50 = 20400 nM
   TI
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   TS
CP0418814
 Compound Info 
4-N-(3-bromophenyl)-7-[(4-phenylphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C25H20BrN5  1
1
IC50 = 13300 nM
   TI
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   TS
CP0421245
 Compound Info 
2,6-dimethyl-N-phenylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C14H13N3O  1
1
IC50 = 48.2 nM
   TI
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CP0428721
 Compound Info 
2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylbenzyl)-pyrrolo[2,3-d]pyrimidine
   Show/Hide
 C21H20BrN5  1
1
IC50 > 500000 nM
   TI
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CP0431280
 Compound Info 
N-[5-chloro-4-(4-chloroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide
   Show/Hide
 C21H19Cl2N5O  1
1
IC50 = 55000 nM
   TI
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   TS
CP0432230
 Compound Info 
N-(2,3-dihydro-1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H17N3O2  1
1
IC50 = 38.3 nM
   TI
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CP0434909
 Compound Info 
N-[2-[[5-chloro-2-[4-[(2-morpholin-4-ylacetyl)amino]anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C25H26ClN7O3  1
1
IC50 = 104 nM
   TI
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   TS
CP0434965
 Compound Info 
N-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]methanesulfonamide
   Show/Hide
 C26H18ClF3N4O3S2  1
1
IC50 = 5250 nM
   TI
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   TS
CP0437753
 Compound Info 
4-N-(3-bromophenyl)-7-[(3,4-dichlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine
   Show/Hide
 C19H14BrCl2N5  1
1
IC50 = 19200 nM
   TI
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   TS
CP0443939
 Compound Info 
3,4-dimethoxy-N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
   Show/Hide
 C28H33N7O5  1
1
IC50 = 11650 nM
   TI
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   TS
CP0465623
 Compound Info 
N-[3-[[4-[3-(4-fluorophenyl)-5-(3-hydroxypropyl)-1,2,4-triazol-4-yl]pyridin-2-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C25H23FN6O2  1
1
IC50 = 65900 nM
   TI
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   TS
CP0467751
 Compound Info 
N-ethyl-N-(4-methoxyphenyl)-5-methylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
IC50 = 3.4 nM
   TI
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   TS
CP0472536
 Compound Info 
N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
   Show/Hide
 C28H29N7O3  1
1
IC50 = 5229 nM
   TI
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   TS
CP0473161
 Compound Info 
N-(3-chloro-4-fluorophenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C14H11ClFN3O  1
1
IC50 = 18 nM
   TI
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   TS
CP0473347
 Compound Info 
N-[2-[4-(dimethylamino)-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-3,4-dimethoxybenzamide
   Show/Hide
 C25H28N6O5  1
1
IC50 = 18150 nM
   TI
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   TS
CP0477484
 Compound Info 
N'-hydroxy-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]butanediamide
   Show/Hide
 C24H28N2O8  1
1
IC50 = 242 nM
   TI
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   TS
CP0478911
 Compound Info 
N-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]acetamide
   Show/Hide
 C27H18ClF3N4O2S  1
1
IC50 = 10500 nM
   TI
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   TS
CP0480461
 Compound Info 
N-(1H-indol-4-yl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H14N4O  1
1
IC50 = 50 nM
   TI
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   TS
CP0482153
 Compound Info 
N-[3-[(3,4-difluorophenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
   Show/Hide
 C20H21F2N3O5  1
1
IC50 = 4010 nM
   TI
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CP0483891
 Compound Info 
N-[2-[[5-chloro-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C24H25ClN6O2  1
1
IC50 = 112 nM
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CP0486082
 Compound Info 
N-[3-[[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
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 C24H25N7O3  1
1
IC50 > 10000 nM
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CP0488677
 Compound Info 
4-(5-methoxyindol-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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 C17H15N3O2  1
1
IC50 > 300 nM
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CP0488682
 Compound Info 
4-(5-methoxy-2,3-dihydroindol-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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 C17H17N3O2  1
1
IC50 = 42.2 nM
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CP0489767
 Compound Info 
N-[3-[(3-fluorophenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyheptanediamide
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 C20H22FN3O5  1
1
IC50 = 4280 nM
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CP0489770
 Compound Info 
N-[3-[(3-ethynylphenyl)carbamoyl]-4-hydroxyphenyl]-N'-hydroxyoctanediamide
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 C23H25N3O5  1
1
IC50 = 6110 nM
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CP0490703
 Compound Info 
N-[2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C25H25ClN6O4  1
1
IC50 = 42 nM
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CP0504740
 Compound Info 
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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 C18H19N3O2  1
1
IC50 = 18 nM
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CP0510836
 Compound Info 
N-(4-methoxyphenyl)-2,6-dimethyl-N-propylfuro[2,3-d]pyrimidin-4-amine
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 C18H21N3O2  1
1
IC50 = 42.3 nM
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CP0510837
 Compound Info 
2,6-dimethyl-N-[4-(trifluoromethyl)phenyl]furo[2,3-d]pyrimidin-4-amine
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 C15H12F3N3O  1
1
IC50 = 55.5 nM
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CP0513310
 Compound Info 
N-[2-[[5-chloro-2-[4-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C26H29ClN6O3  1
1
IC50 = 584 nM
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CP0516900
 Compound Info 
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)quinazoline
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 C18H17N3O  1
1
IC50 = 16.3 nM
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CP0520799
 Compound Info 
N-[3-[[2-[4-[4-(diethylamino)piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
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 C30H38N8O3  1
1
IC50 = 2011 nM
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CP0521635
 Compound Info 
N-[3-[[5-chloro-2-[2-methoxy-4-(4-morpholin-4-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
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 C30H35ClN8O4  1
1
IC50 = 2592 nM
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CP0523032
 Compound Info 
N-[3-[(3-ethynylphenyl)carbamoyl]-4-methoxyphenyl]-N'-hydroxyheptanediamide
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 C23H25N3O5  1
1
IC50 = 4200 nM
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CP0526577
 Compound Info 
N-ethyl-N-(4-methoxyphenyl)-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine
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 C17H19N3O2  1
1
IC50 = 50.1 nM
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CP0548535
 Compound Info 
N-(4-methoxyphenyl)-5-methylfuro[2,3-d]pyrimidin-4-amine
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 C14H13N3O2  1
1
IC50 = 292.1 nM
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CP0560106
 Compound Info 
(E)-1-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-8,9-dihydro-7H-pyrimido[5,4-h][1,5]benzoxazepin-6-yl]-4-(2-methylpiperidin-1-yl)but-2-en-1-one
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 C34H35ClFN5O3  1
1
IC50 > 10000 nM
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CP0561775
 Compound Info 
N-[3-[[2-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
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 C28H34N8O3  1
1
IC50 = 3379 nM
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CP0567338
 Compound Info 
N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-(3-nitrophenoxy)pyrimidin-4-amine (14)
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 C19H22N8O3  1
1
GI50 = 3500 nM
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CP0570582
 Compound Info 
(E)-1-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-8,9-dihydro-7H-pyrimido[5,4-h][1,5]benzoxazepin-6-yl]-4-(diethylamino)but-2-en-1-one
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 C32H33ClFN5O3  1
1
IC50 > 10000 nM
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CP0639837
 Compound Info 
8-[2-methoxy-5-(4-methylpiperazin-1-yl)anilino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
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 C23H28N8O2  1
1
IC50 = 10 nM
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CP0691433
 Compound Info 
N-(2-aminophenyl)-4-{[4-(3-bromophenylamino)quinazoline-6-yloxy]-methyl}benzamide
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 C28H22BrN5O2  1
1
IC50 = 1700 nM
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CP0727218
 Compound Info 
5-[(Z/E)-2-(20-Methoxyphenyl)pent-1-en-1-yl]furo[2,3-d]-pyrimidine-2,4-diamine
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 C18H20N4O2  1
1
IC50 > 500000 nM
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CP0850024
 Compound Info 
N-(2-aminophenyl)-N5-(4-(3-ethynylphenylamino)-quinazoline-6-yl)pyridine-2,5-dicarboxamide
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 C29H21N7O2  1
1
IC50 > 16000 nM
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CP0850025
 Compound Info 
N2-(2-aminophenyl)-N5-[4-(3-ethynylphenylamino)quinazolin-7-yl]thiophene-2,5-dicarboxamide
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 C28H20N6O2S  1
1
IC50 = 960 nM
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CP0856507
 Compound Info 
N2-(2-aminophenyl)-N5-(4-(3-ethynylphenylamino)quinazolin-6-yl)thiophene-2,5-dicarboxamide
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 C28H20N6O2S  1
1
IC50 > 16000 nM
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CP0877991
 Compound Info 
7-Benzyl-N-(4-methoxyphenyl)-2,5-dimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
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 C22H23ClN4O  1
1
IC50 = 2.3 nM
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CP0897293
 Compound Info 
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
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 C24H25ClN4O  1
1
IC50 = 40.1 nM
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CP0905765
 Compound Info 
Octanedioic acid hydroxyamide((S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-amide
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 C28H36N2O8  1
1
IC50 = 3430 nM
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CP0906525
 Compound Info 
1-(7-Benzyl-2,5-dimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
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 C25H27ClN4O  1
1
IC50 = 8.1 nM
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CP0910394
 Compound Info 
(S)-2-phenyl-2-((6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)ethan-1-ol
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 C20H18N4O  1
1
IC50 = 300 nM
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CP0957322
 Compound Info 
(S)-2-((6-(4-(((2-(Dimethylamino)ethyl)amino)methyl)-3-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-phenylethan-1-ol
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 C25H29FN6O  1
1
IC50 > 10000 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Skin)
Cell Line Name Organism Disease
A-375
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
A375-P
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
A375-SM
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SK-MEL-28
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
EBC-1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
WM115
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM266-4
 Cell Line Info 
Homo sapiens (Human) Melanoma
G-361
 Cell Line Info 
Homo sapiens (Human) Melanoma
UACC-62
 Cell Line Info 
Homo sapiens (Human) Melanoma
SK-MEL-2
 Cell Line Info 
Homo sapiens (Human) Melanoma
Mt2-4
 Cell Line Info 
Homo sapiens (Human) Mitochondrial diabetes
NMIi005-A
 Cell Line Info 
Homo sapiens (Human) Schizophrenia
FF
 Cell Line Info 
Mesocricetus auratus (Golden hamster) Hamster melanoma
B16-F10
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-BL6
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-F1
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
B16-F0
 Cell Line Info 
Mus musculus (Mouse) Mouse melanoma
HaCaT
 Cell Line Info 
Homo sapiens (Human) -
HFF
 Cell Line Info 
Homo sapiens (Human) -
S12 [Human keratinocyte]
 Cell Line Info 
Homo sapiens (Human) -
Malme-3
 Cell Line Info 
Homo sapiens (Human) -
BJ [Human fibroblast]
 Cell Line Info 
Homo sapiens (Human) -
HMEC-1
 Cell Line Info 
Homo sapiens (Human) -
297L1
 Cell Line Info 
Homo sapiens (Human) -
HaCaT-ARE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Melan-a
 Cell Line Info 
Mus musculus (Mouse) -
JB6 Cl 41-5a
 Cell Line Info 
Mus musculus (Mouse) -